Background and Objective: Coronavirus disease 2019 (COVID-19) can lead to organ failure by the occurrence of mechanisms such as increased thrombosis and, subsequently, increased lactate dehydrogenase (LDH). This study was conducted to determine LDH serum levels in COVID-19 patients and the factors affecting their mortality.
Methods: This descriptive-analytical study was conducted on 212 patients (57 males and 155 females) with COVID-19 with a mean age of 49.19±10.6 referring to Imam Ali Hospital in Chabahar, Iran during 2021. After obtaining patients’ informed consent and demographic information, the heparinized peripheral blood sample was taken from them. The LHD levels were determined using an autoanalyzer.
Results: Twenty-nine (13.67%) patients died. The mean LDH serum level of 29 deceased patients (708.420±96.25 U/L) was not statistically significant compared to survivors (640.360±96.80 U/L in 183). The comparison between the surviving and deceased groups showed that 25% of the deceased patients were hospitalized in the intensive care unit (ICU), and 90.90% of the survivors were hospitalized in the internal ward (P<0.05). All the deceased and 85.85% of the survivors were 40 years old and above, and this difference was not statistically significant. Furthermore, 24.56% of the deceased were male, 90.32% of the survivors were female (P<0.05), 22.72% of the deceased had a university education, and 88.69% of the survivors had a diploma or under-diploma education (P<0.05), and 71.42% of the deceased patients had thin, and 91.37% of the survivors were overweight (P<0.05).
Conclusion: There was no difference in the LDH serum levels of the COVID-19 survivors and deceased. The age of 40 years and above, lean and morbidly obese body mass indices, male gender, and the need for hospitalization in the ICU were determined as risk factors.

Background and Objective: The outbreak of coronavirus disease 2019 (COVID-19) has had many psychological impacts on the relatives of patients with COVID-19, which can influence their physical health. This study was conducted to determine Obsessive-Compulsive Disorder (OCD) and its link to the physical health of relatives of patients with COVID-19.
Methods: This case-control study was conducted on 98 relatives of patients with COVID-19 (the case group) with a mean age of 38.56±9.09 years and 98 family members without patients (the control group) with a mean age of 35.79±9.88 years referring to health centers in Gorgan, Iran during 2022. The subjects were selected by a simple random sampling method after extracting the list of patients with COVID-19 from the Health Information Software (NAB) system of health centers. For each selected case, according to the list of families in the NAB system, a family confirmed with a lack of COVID-19 infection was selected as the control group using the simple random sampling method. The data collection tools included the Yale-Brown obsessive-compulsive scale (Y-BOCS) and the patient health questionnaire-15 (PHQ-15).
Results: The mean OCD score in the case group (6.46±5.87) was significantly higher than that in the control group (2.04±3.76) (P<0.05). The mean physical health disorder of the case group (7.60±4.32) was significantly higher than that in the control group (3.43±3.98) (P<0.05). A significant direct linear correlation was found between OCD and physical health in both groups (r=0.39, P<0.001).
Conclusion: The levels of OCD and physical health disorders were significantly higher in family members with a COVID-19 patient than in family members without a COVID-19 patient.