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Showing 2 results for Burn Wound

Ghr.hasanzadeh (phd), A.nori (md), M.hajiabadei (md), K.soltan (md), A.javadei (msc),
Volume 7, Issue 2 (10-2005)
Abstract

Background&Objective: Burning and burn wound are the causes of mortality in the world. The present study was designed to investigate the effect of egg yolk (of hen) on burn wound healing in Rats. Materials&Methods: In this experimental sutdy, 48 females rats randomely divided in silver sulphadiazin, egg yolk and control groups, respectively. Each of three groups including 16 rats and was selected for 28 days of treatment. After general anesthesia with ketamin and xylazin (ip) an area of the back of rats was burned with red-hot coin and similar grade II burns were created. Control group received no medication. In the second and third groups, the surface of wound was covered daily with sulphadiazine and egg yolk. At the end of the eack week, four rats from the each group were scarified by ether and samples were taken from the wound region and were histologically assessed. The samples were stanied with Hematoxillin and Eosin and studied quantitively. Results: Results showed that after 4 weeks the healing of burn wounds in the groups receiving egg yolk and sulphadiazine were similar. But healing of burn wounds within these 2 groups was better than control group. There was no difference between the groups receiving either egg yolk or sulphadiazin. Conclusion: This study showed that egg yolk can be used as an alternative to sulphadiazin in second degree burn wounds.
Aria Afshari , Mahdieh Raeeszadeh , Loghman Akradi ,
Volume 20, Issue 1 (3-2018)
Abstract

Background and Objective: Burn is one of the leading causes of mortality in the world. This study was done to determine the effect of the lavender, sesame oil, and combination of Lavender with sesame oil and silver sulfadiazine on the burn wound healing in mice.
Methods: In this experimental study, 30 male adult albino mice were randomly allocated into 5 groups as follows: the negative control group (physiology serum); the positive control group (silver sulfadiazine); the first experimental group (sesame oil), the second experimental group (combination of Lavender with sesame oil) and the third experimental group (Lavender oil).Second degree of  burn wound healing  take place using hot sheet with a diameter of 2 cm. wound treatment was done in five groups in 21-day treatment period. The wound diameter size and restoration percentage were measured on days 1, 3, 6, 9, 18, and 21. Some mice were euthanized and the samples of wounds were used for histopathological studies.
Results: The percentage of wound healing significantly increased in groups of silver sulfadiazine, combination of Lavender with sesame oil, Lavender oil and  sesame oil in compared to control group (P<0.05). The improvement percentage was seen in sulfadiazine and combination of Lavender with sesame oil groups in compared to negative control group. The level of tissue restoration based on the accumulation of collagen, fibroblasts, re-epithelialization were seen in sulfadiazine, combination of Lavender with sesame oil, Lavender oil and sesame oil, respectively.
Conclusion: Combination of Lavender with sesame oil similar to silver sulfadiazine has tissue restoration effect on burn wound healing in animal model.

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مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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