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Background&Objective: Comorbidity between ADHD (Attention Deficit Hyperactivity Disorder) and major depression has been reported from both epidemiologic and clinical studies of both children and adults. With the use of family study methods, we tested hypotheses about patterns of familial association between attention deficit hyperactivity disorder (ADHD) and depressive disorder among first-degree relatives of clinically referred children and adolescents with ADHD. Materials&Methods: In this case – control study, were 208 probands with ADHD (aged 5-17 yrs) were diagnosed by clinical interview and the Schedule for Affective Disorders and Schizophrenia for School–Age Children Present and Lifetime version (K–SADS–PL), and they were assessed for major depression with interview and K- SADS. 779 first degree relatives (416 parents, 363 siblings) were assessed with interview and K- SADS (for under 18 yrs) and SADS (for age up to 18 yrs) and Wender (for age up to 18 yrs) for major depression and ADHD. Results: Familial risk for ADHD was similar in the relatives of the ADHD probands. The risk for major depression disorder was three times higher in relatives of probands who had ADHD with depressive disorder than in those of the ADHD probands without depressive disorder. There was a tendency for ADHD probands' relatives who themselves had ADHD to have a higher risk for depressive disorder than ADHD probands' relatives who did not have ADHD (cosegregation). Conclusion: These findings are consistent with the hypothesis that ADHD and major depression disorder cosegregate within families.

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Background & Objective: ADHD is the most common mental disorder in children. Awareness of students' mental health has an important role in programming for decrementing their disorders and, improving their mental health and also preventing the complications of their decreased mental health. The aim of this study was to determine the prevalence of ADHD and some of the affecting factors among school children in Nishaboor localed in the North – East of Iran. Materials & Methods: This descriptive study was done on school children in Nishaboor during 2006. Subjectes selected by stratified cluster sampling. Data collection was done using the Conner's Parent and Teacher Scale questionnaire, and each student's questionnaires were completed by both the teacher and the parents. Data analysis was performed regarding to the mean scores of teachers and parents. The score 15 was chosen as the probable indicator for ADHD. Results: 722 students (79.6%) were involved this study. Prevalence of ADHD was 12.5%, CI95%: 10–14.8%. There was no significant difference in gender distribution. The prevalence of ADHD had a significant rise with age (P<0.05). The highest prevalence was in spring born and the lowest was in the summer born school children (P<0.05). The prevalence of ADHD had a significant relationship with father's education and was lower in students whose father had higher educations (P<0.05). Variables such as type of delivery, pariety, mother's education had no significant relationship with the prevalence of ADHD. Conclusion: In this study the prevalence of ADHD is higher than similar studies. Risk groups to be followed up by the responsible organizations.

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Background and Objective: According to destructive consequences of untreated attention deficit hyperactivity disorder (ADHD), this study was done to evaluate of the prevalence of adult ADHD and its relation with depression among Iranian students. Methods: This descriptive study was carried out on 414 students of Kerman University of Medical Sciences, Kerman, Iran during 2010-11. ADHD was screened by ADHD self report scale for adult ADHD and asking DSM-IV criteria from parents for childhood ADHD. Beck depression inventory questionnaire was used to determine depression. Results: The prevalence of adult ADHD and childhood ADHD was 3.9% and 8.5%, respectively. Depression was more prevalent in those with adult or childhood ADHD. Depression was more prevalent in under graduate than post graduate students (P<0.05). Conclusion: Depression is more prevalent in students with adult ADHD or with history of childhood ADHD.