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Background&Objective: Stress in managers will effect and destroy the immune system on mental health. Clinical studies have revealed that, social support is one of the moderating factors of negative effect of stress on immune system. The aim of this research was study the correlation between social support and immune system of high school managers in khozestan province. Materials&Methods: An experimental study was conducted on 360 male and femal managers who were participated. Then randomly two groups (n=80 in each group) of low and high social support were selected. Subjects who suffered from disorders that affected the immune system were excluded. Number of T-helper cells (CD4), T-suppressor cytotoxic cell (CD8), Natural killer cells (CD56+CD16), Complement system (C3,C4,CH50), Immunoglobulin M and G (IgM&IgG), cortisol hormone, Eosinophils, Neutrophils and Lymphocytes were measured. Results: There was a significant positive correlation between social support and CD4, CD4/CD8, NK cell (CD56+CD16), CH50, IgM and Neutrophils. Also there was a significant negative correlation between social support and CD8, cortisol and Eosinophils. There was a significant difference between high and low social support managers in CD4, CD4/CD8, CD8, cortisol, CH50, C4, C3 and Lymphocytes. Conclusion: The results indicated that social support has a positive significant correlation with those immune cells that improve the immune system and has a negative correlation with those immune cells that decerase the immune system. In fact the social support is a moderating factor angainst stress and its negative effects on immune system.

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Background and Objective: Cognitive behavioral therapy based on religion can increase the religious mind. This study was done to evaluate the effectiveness of cognitive behavioral therapy based on religion on depression and quality of life in patient with HIV/AIDS.

Methods: In this quasi -experimental study with pretest, post test and follow up with control group, 30 patients with HIV were non-randomly divided into intervention and control groups. Patients in intervention group were received 12 sessions of cognitive behavioral therapy based on religion, but patients in control group did not receive any intervention. Beck depression test (BDI-II) and quality of life questionnaire (WHOQOL-Brief) were used.

Results: The rate of depression in intervention group significantly reduced in compared to controls (P<0.05). The rate of quality of life significantly increased in intervention group in comparision with controls group (P<0.05). These results significantly persisted after follow- up period (P<0.05).

Conclusion: The cognitive behavioral therapy based on religion is effective on decrease of depression and increase of quality of life in patients with HIV/AIDS.