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Background and Objective: Nausea and vomiting are the most frequent complications in the first trimester of pregnancy. Herbal medicine is among the traditional effective treatments. Ginger and Chamomile are hypothesized to be useful in decreasing the signs. This study was done to determine the effect of Ginger and Chamomile capsules on nausea and vomiting in pregnancy.

Materials and Methods: This triple-blind randomized placebo-controlled trial was carried out on 105 pregnant women in 6-16 weeks of gestational age with a mild to moderate nausea and vomiting, whome referred to the prenatal care clinic in Dezyani hospital and health centers, Gorgan, Northern Iran during 2009-10. Rhodes index questionnaire had been given to all participants to be completed before bed-time for two weeks. In the first week no intervention was done and prescribing the capsules was started the following week. Subjects randomly divided into 3 groups: In group 1, ginger capsules were consumped twice a day for one week, in group 2 twice daily chamomile capsule and in placebo group, glucose capsule was prescribed. Scores were calculated and all data were entered into the SPSS-16 software, analysis was done using variance analysis, Will-Cockson, paired T and Fisher-exact tests.

Results: The mean of Rhodes index before intervention in plasbo, Ginger and Chamomile groups were 12.71±5.88, 10.42±0.76 and 11.19±5.51, respectively. Also, the mean of Rhodes index after intervention in plasbo, Ginger and Chamomile groups were 11.47±6.43, 7.28±3.74 and 5.73±4.32, respectively (P<0.05). Bonferroni test indicated that there is no difference about scor chang (after and before) between Ginger and Chamomile and Ginger and plasbo, but this difference was significant between Chamomile and plasbo group (P<0.05).

Conclusion: This study showed that Chamomile capsule was more effective on nausea and vomiting during pregnancy compared to Ginger.

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Background and Objective: Ginger as a medicinal herb is used as a food flavoring and thraphy of many diseases including infertility and male sexual disabilities. This study was carried out to evaluate the effect of alcoholic extract of Ginger during fetal life and breastfeeding on serum level of testosterone, LH, FSH and spermatogenic cell lines in male mature offspring rats. Methods: In this experimental study, 72 female adult mice were randomly allocated into the 9 groups, including: control group (no treatment), sham groups including neonatal and perinatal groups which were received normal salin (0.5 ml daily) and 6 interventional groups. Animals in interventional groups were received doses of 50, 100 and 200 mg/kg/bw of alcoholic extract of Ginger, during neonatal and perinatal period, orally. After puberty eight male rats from each group were sacrified. Serum level of testosterone, LH, FSH were measeared and then by isolating testes, the cell numbers of leydig, sertoli, spermatogonia, spermatocyte and spermatid were counted. Results: The extract of Ginger dose-dependently significantly increased the level of testosterone (P<0.05) and the number of spermatogenic cells in compared to controls (P<0.05). The dosage of 100 and 200 mg/kg/bw of alcoholic extract of Ginger significantly reduced the FSH and LH in compared to controls (P<0.05) Conclusion: The oral consumption of Ginger during pregnancy and lactation dose-dependently increase the level of testosterone and the number of spermatogenic cells.

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Background and Objective: Life style with Low activity and overweight increased the risk of cardiovascular diseases. This study was done to evaluate the effect of ginger supplementation on Lactate dehydrogenase (LDH) changes and delayed muscle soreness following exhaustive eccentric exercise on overweight girls.
Methods: In this randomized clinical trial study, 22 overweight girls were randomly divided into the two groups including intervention (n=12) and control (n=10) groups. For subjects in interventional group were used a daily supplement of 2 grams of ginger powder, each serving a capsule, containing one gram of ginger powder  and subjects in control group were received  daily two capsules containing starch, for two weeks. Physical activity was performed consisting of two sessions of exhausting activity (negative tilt on treadmill, one session before supplementation and one session after two weeks of supplementation). Blood samples were measured in order to measure changes in LDH in four stages and the use of the pain questionnaire for evaluation of delayed muscular brittleness in both pre and post gingival supplementation. Pain scale (visual analogue scale: VAS) was used to measure the delay fatigue.
Results: The results showed that extrinsic exercise increased LDH and delayed muscle soreness after exercise (P<0.05). Also, taking two weeks of ginger supplementation significantly reduced LDH and delayed muscle soreness in the supplement group in comparison with controls (P<0.05).
Conclusion: Ginger can reduces the muscle gain and delayed onset muscle soreness resulting from eccentric exercise in overweight girls.