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Showing 2 results for Pashazadeh

Farhad Pashazadeh, Asghar Tofighi , Siyamak Asri Rezaei , Javad Tolouei Azar ,
Volume 22, Issue 4 (12-2020)

Background and Objective: Bisphenol A (BPA) is the monometer of epoxy resins and polycarbonate plastics that plays an important role in the pathogenesis of cardiovascular diseases. This study was done to evaluate the effect of aerobic exercises on oxidative stress indices in heart tissue of male Wistar rats after poisoning with Bisphenol A.
Methods: In this experimental study, 20 adult male Wistar rats were allocated into four groups including control, aerobic exercise, BPA and BPA + aerobic exercise. Animals in control and aerobic exercise groups were receieved olive oil and the BPA (100 μg/kg) intraperitoneally, respectively. Animals in BPA + aerobic training group were treated with BPA (100 μg/kg) intraperitoneally for 30 days. Exercise program consisted of 25-64 minutes of running with 57-75% oxygen consumption, 5 sessions per week for two months. Indicators of oxidative stress in heart tissue including Gpx, SOD, TAC, MDA, CAT and AOPP were evaluated.
Results: BPA intoxication induced a significant increase in the activity of SOD , GPX enzymes, AOPP and MDA levels and  reduction  in CAT enzyme activity and TAC level in compared to control group (P<0.05). While aerobic exercise could diminish the oxidative stress due to BPA intoxication. Aerobic exercise reduced the activity of the GPX, SOD and increased catalase activity in rats with BPA intoxication (P<0.05). Also, level of MDA and AOPP significantly reduced in in aerobic exercise group in comparison with with BPA intoxication (P<0.05).
Conclusion: Aerobic exercise activity has moderating effects on BPA intoxication in cardiac oxidative stress. Aerobic exercise can increase the amount of antioxidant enzymes that play an important role in modulating oxidative stress induced by BPA.
Ahmad Reza Yousef Pour Dehaghani , Farhad Pashazadeh , Morteza Naji,
Volume 24, Issue 1 (3-2022)

Background and Objective: Having a proper diet is very important. Many risk factors are involved in the development of cardiovascular disease that by changing them, the incidence of this disease can be reduced. This study was performed to determine the relationship between nutritional knowledge and level of physical activity with the prevalence of metabolic syndrome and some cardiovascular risk factors in militaries men.
Methods: This descriptive-analytical study was performed on 97 athletes and non-athletes militaries men. The standard Parmenter and Wardle Nutrition Knowledge Questionnaire of 1999 and Baecke Physical Activity Questionnaire were completed. Subjects' fitness scores and physical indicators were measured. Prevalence of metabolic syndrome, based on revised ATP ш and IDF was calculated.
Results: The mean nutritional knowledge of the subjects was moderate to low. There was a significant correlation between the nutritional knowledge, level of physical activity and fitness score and cardiovascular risk factors (P<0.05). Also there was a significant correlation between the nutritional knowledge, level of physical activity and fitness score with preventing metabolic syndrome (P<0.05).
Conclusion: With increasing nutritional knowledge, physical activity and fitness scores the risk of cardiovascular factors reduces and the possibility of metabolic syndrome prevention increase.

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مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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