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Showing 2 results for Hassanpour

Hassanpourfard M, Naseh G, Lotfi N , Hosseini M,
Volume 17, Issue 4 (12-2015)

Background and Objective: Diabetes meltius is a metabolic disorder which characterized with disorder in carbohytdrate and lipid metabolism. This study was conducted to evaluate the effect of aqueous extract of turnip root (Brassica rapa) on glucose and lipid Profile in alloxan-induced diabetic rats. Methods: In this experimental study 40 male wistar rats randomly allocated into 5 equal groups including diabetic control, Metformine 50mg/kg, 200mg/kg and 400 mg/kg/bw of aqueus extract of turnip root and normal control groups. Alloxan monohydrate 150 mg/kg/bw was used to induce diabetes mellitus and two weeks after Alloxan injection rats with fasting blood sugar (FBS) more than 350mg/dl considered as diabetic rats. All administrations were done orally and daily in a same volume for 28 consecutive days. The FBS concentrations were determined on the first, 14th and 29th days. On 29th day, blood was collected from overnight fasted rats. Plasma concentrations of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), low density lipoprotein cholesterol (LDL-c), aspartate amino transfarase (AST) and alanine amino transferase (ALT) activities were measured. Results: The statistical data indicated (P<0.05) in the levels of FBS (4.5 times), TC, TG, AST and ALT (about 2.5 times) and LDL-c (2 times) significantly increased in diabetic rats compare to healthy normal control group. Administration of 200mg/kg and 400 mg/kg/bw of turnip root extract did not exhibit hypoglycemic activity. Turnip root extract significantly inhibited the increasing of TC, TG, LDL-c and ALT in diabetic rats (P<0.05), but had no effect on AST sera level. Conclusion: Although, the aqueous extract of turnip root had not any hypoglycemic activity but it was effective in reduction of TC, TG, LDL-c and ALT in diabetic rats.
Mohammad Mehdi Soltan Dallal , Mohammad Kazem Sharifi Yazdi , Alireza Monadi Sefidan , Gholamreza Hassanpour , Sara Sharifi Yazdi, Shabnam Haghighat Khajavi , Saeed Vahedi , Seyedeh Masoomeh Abrichamchian Langaroudi , Mahdieh Pourmoradian , Hedroosha Molla Agha Mirzaei ,
Volume 24, Issue 1 (3-2022)

Background and Objective: Yersinia is water and foodborne organism that cause human gastroenteritis. This study was done to evaluate the frequency of Yersinia species isolated from children diarrheal samples and chicken meat in Tehran, Iran.
Methods: In this descriptive study 250 sample of diarrhea of children referred to the Children's Medical Center, Tehran, Iran and 250 samples of chicken were collected and examined for Yersinia infection during July 2016 to March 2017. Isolation method was performed based on initial enrichment in phosphate buffer for 3 weeks in refrigerator (cooling in c4 +) and then using KOH as secondary enrichment and culture on CIN agar medium. Biotyping method was used to determine pathogenic strains.
Results: In this study, 5(2%) isolates from pediatric diarrhea samples and 20 isolates (8%) from chicken meat samples were obtained from Yersiniaenterocolitica. Biotyping of human Yersiniaenterocolitica isolates identified 3 cases of biotype 1A, one case of biotype 1B, one case of biotype 2 and from chicken meat isolates, 16 isolates belonged to biotype 1A and 4 isolates belonged to biotype 1B.
Conclusion: Presence of common pathogenic 1B and non-pathogenic 1A biotypes in pediatric diarrhea samples and chicken meat can indicate the cause of diarrhea in children.

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مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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