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Showing 17 results for Abdolahi

Hr.tajari (m.d), B.ghazi-Moghaddam (m.d), S.vahedi (m.d), N.abdolahi (m.d), R.davoodi (m.d), A.abedini (m.d),
Volume 5, Issue 2 (Autumn & Winter 2003)
Abstract

Background & Objective: Enuresis is a problem in children. In this research the success, rate and recurrence of Imipramine, Desmopresine and conditional therapy has been studied in enuresis treatment of children. Materials & Methods: This study was done on 84 enuresis child between 7-11 years old which were selected by screening at the schools. Patients divided randomly to 3 groups: The 1st group received 25 mg of Imipramine every night. The 2nd group was treated with 20 micg of Desmopresine intranasaly every night. The 3rd group used alarm for conditioning every night. All groups were treated for one month, and 2 weeks without enuresis meaned success. Results: All physical finding and laboratory tests were normal in all patients (FBS, U/A, U/C, kidney and bladder sonography). Patients had in average 8.5 years old. 77.3% of cases were boys and 22.7% were girls. Success rate for therapy was 71.4%, 60% and 50% in-groups 1-3 respectively. Recurrence rate 6 months after therapy was 10%, 55.5% and 25% in-groups 1-3 respectively. Conclusion: Imipramine persists as cheep, available, well-tolerated and effective way of treating enuretic patients. Due to high recurrence rate, Desmopresine is just recommended as a temporary treatment.
Sh.semnani (m.d), V.kazeminezhad (m.d), N.abdolahi (m.d),
Volume 5, Issue 2 (Autumn & Winter 2003)
Abstract

Background & Objective: Colorectal cancer is the most common cancer of GI and 2nd most common cause of cancer death in the world. The purpose of this study was to determine epidemiologic aspect and tumor characteristics of colorectal cancer for patients and compare them in young (<50 yr) and older (>50 yr) patients. Materials & Methods: In this cross-sectional study during 3 yr the samples of malignant colorectal cancer presented in Gorgan endoscopy and pathologic centers were collected. Data evaluated by statistically method. Results: There were 101 cases of malignant colorectal cancer. 61 cases were male and 40 cases were female. The mean age was 56±13.65 yr. 13.9% of patients were <40 yr. The type of tumor in 94% was adenocarcinoma, 2.9% lymphoma and 2.9% undifferentiated carcinoma. The site of involvement in 30 cases were rectum and in 71 cases were colon. The most common symptom was abdominal pain, constipation and rectal bleeding. The time interval between onset of symptom to diagnosis of disease in 58 cases was >6 mth. Family history of cancer in 36 cases was positive. Right colon cancer in young patient was significantly more than older (P<0.05). Positive family history of cancer in right colon cancer was significantly more other than. Positive family history of cancer in young patient was more than other (P<0.05). Conclusion: According to this study, colorectal cancer was high. Therefore, it is necessary to pay more attention to the symptom of young patient and providing a screening program in patients over 50 years old and young patients with positive family history.
Semnani Sh, Besharat S, Rafiee S, Keshtkar Aa, Roshandel Gh, Abdolahi N, Jabbari A,
Volume 8, Issue 3 (10-2006)
Abstract

Background&Objective: 15-20% of TB cases are extra pulmonary tuberculosis (EPTB). Abdominal TB is the most common type of extra intestinal TB. Signs and symptoms of abdominal TB are unspecific. In this study, we identified all GITB cases in Golestan province (Iran) between 1999 and 2003 and determined their demographic characteristics. Materials&Methods: We reviewed all new cases of TB reported during 1999-2003 from TB centers of Golestan province .Then EPTB and especially GI and abdominal TB cases were selected. We completed a questionnaire containing demographic information for each of them. The information entered the computer in SPSS-13 was used to analyze the data. Results: 30 patients had been treated for GI and abdominal TB, most of them were females (22 cases, 73.3%). Mean age of the patients was 32.03±13.73 with higher incidence in age before 40 years old (70%). Most common complaints of the patients were fatigue, weight loss, anorexia, fever and abdominal pain, respectively. In 66.7% of patients the diagnosis was pathologically documented. Conclusion: Our data suggest that 38.46% of all TB cases in Golestan province were EPTB, and this scale is higher than other studies. In this study, 5.27% of EPTB cases were GI and abdominal TB, higher than the world reports (3%).
Joshaghani Hr, Semnani Sh, Mirrezaee A, Abdolahi N, Besharat S, Behnampour N, Dehbashi Gh, Roshandel Gh,
Volume 8, Issue 3 (10-2006)
Abstract

Background&Objective: Celiac is a digestive disease. In this disease, small bowel is damaged and the absorption of nutrients are adversely affected. These patients do not absorb gluten. There is probably a correlation between esophagus cancer and celiac. The aim of this research was to study the seroepidemiology celiac disease in this area with high prevalency of esophagus cancer. Materials&Methods: This research was a descriptive study, which was performed on blood donors in Golestan province during the year 2005-06. blood samples were taken from 2547 subjects. tTG-IgA determination were carried out using ElISA technique, the titre<4U/ml, 4-10U/ml and >10Um/l were considered to be as negative, weakly positive and positive respectively. EMA antibody assessment were carried out on all sample population with more than 4U/ml, using IFA method. Results: 28 subjects (1.1%) had tTG-Ab positive test, out of this number 18 subjects (0.7%) were weakly positive and 10 persons (0.4%) were considered to be positive. EMA test were positive in 70% of subjects with tTG positive results. There was not any significant meaning between positive tTG test and ethnicity from weakly positive tTG, 15 subjects (83.3%) and 3 subjects (16.7%) were male and female respectively. The entire tTG positive were male subjects. Conclusion: In regard to high prevalency of esophagus cancer in the region and the relation of celiac disease with above cancer, it seems necessary to look more seriously at the celiac disease.
Semnani Sh, Besharat S, Jabbari A, Keshtkar Aa, Abdolahi N, Roshandel Gh, Yazdi Hr,
Volume 8, Issue 4 (12-2006)
Abstract

Background&Objective: Silis (SiO2) is an oxide of silicon that its existence in food products is known as a contamination, classified as a human carcinogen. Some suggest it as an etiology of esophageal cancer. Golestan province has a high incidence and prevalence of esophageal cancer and is on the world belt of this disease. This study was designed to determine the concentration of silis in flour produced in Golestan province, north of Iran Materials&Methods: This descriptive study was done in spring 2005. Census method was used to gather flour samples from flour manufactures. Samples were transported to laboratory. Base-melting method in nickel cruise was used in 550°c and the extract was reduced with acid. The complex was evaluated with spectrophotometer. Data entered into SPSS-12, and the differences between silis concentration in various regions were compared with non-parametric Kruskul Walis test. Results: Median silis concentration was 0.0030 grams, mean concentration was 0.008760 with 0.004265 standard deviation, minimum was 0.003 and maximum was .018 grams in each 100 grams flour produced in province's factories. Mean silis concentrations were 0.012, 0.01 and 0.003 in Gorgan and the central part of the province, western and eastern part, respectively. The differences were not significant. Conclusion: Although in earlier reports it was shown that silis level in the flour is high, but the findings of this study indicated that the above element is in normal range.
Rogheieh Golsha, Gholamreza Roshandel, Rahim Rezaie Shirazi, Danyal Roshandel, Nafiseh Abdolahi, Ali Jabbari, Sima Besharat, Shahryar Semnani,
Volume 9, Issue 4 (12-2007)
Abstract

Background & Objective: The Acquired Immunodeficiency Syndrome (AIDS) is in its third decade and has become a pandemic disease that threatens the world population. Educational programs are well known as the most effective strategy to preventing the AIDS. The purpose of this study was to determine the knowledge and attitude of participants about AIDS and to test the effects of an AIDS education program on it. Materials & Methods: This case-control study was conducted during 2005. 149 Red Crescent personnel in Golestan, Iran. The sample subjects participated in a pre/post intervention study. The activity consisted of a workshop 90 minutes in length, in conjunction with educational material. A 13-item questionnaire was used as the gauging tool. Results: 47% of subjects had adequate knowledge about AIDS. Mean level of knowledge in post-test exam was significantly higher than pre-test one (P<0.0001). Individuals with higher educational level (high school and university) had lower knowledge in pre-test (P=0.001), but the difference in pos-test was not significant. A significant relationship was shown between the history of participation in previous AIDS education programs and subject's knowledge in pre-test (P<0.001). Conclusion: This study indicated that education program based on special traing considerably increase general awareness and attitde towards AIDS.
Gholamreza Roshandel, Shahryar Semnani, Nafiseh Abdolahi, Sima Besharat, Abbas Ali Kashtkar, Hamid Reza Joshaghani, Abdolvahab Moradi, Khodaberdi Kalavi, Saba Besharat, Ali Jabbari, Mohammad Javad Kabir, Seyed Ahmad Hosseini, Seyed Mahdi Sedaghat, Danyal Roshandel, Ahmad Danesh,
Volume 9, Issue 4 (12-2007)
Abstract

Background & Objective: Hepatitis B virus (HBV) infection is one of the most important health problems all over the world. This study was conducted to determine the co-infection of hepatitis C virus (HCV), hepatitis D virus (HDV) in HBV infected patients in Golestan province of Iran. Materials & Methods: This population based cross sectional study was done in 2004. 139 HBsAg positive cases were assessed for co-infection with HCV and HDV. Serologic tests were done by ELISA method using available kits. Data were analyzed by SPSS-12 and STATA8 software. P-values of less than 0.05 were considered as significant. Results: Sixty eight (48.9%) of 139 cases were males and 71 (51.1%) were females. The mean (±SD) of participant's age was 41.89 (±11.3) years (range: 25-64 years). Anti-HCV and Anti-HDV antibodies were positive in 17 (12.3%) and 8 (5.8%) cases, respectively. Females were more infected with HCV and HDV than males. But the differences were not significant. Conclusion: The prevalence of co-infection with HCV and HDV in HBV infected cases is relatively high and notable in Golestan province of Iran. Because of negative effects of these co-infections in clinical outcome of the disease, it is recommended to assess possible HCV and HDV infection in individuals with HBV infection. This may result in more efficient management of the disease.
Shahryar Semnani (md), Sima Besharat (md), Abbas Ali Kashtkar (md, Phd), Ahmad Danesh (md, Phd Student), Nafiseh Abdolahi (md), Gholamreza Roshandel (md), Ahmad Hoseyni (md,mph), Mehdi Sedaghat (md, Mph),
Volume 10, Issue 3 (10-2008)
Abstract

Background and Objective: Esophageal and gastric cancers are among the most common and fatal cancers. These are diagnosed at the latest phase and the prognosis is too poor. Due to the importance and high incidence rate of the upper gastrointestinal cancers in Golestan province, this study was conducted to explore the overall survival rate of these patients in rural area of this region. Materials and Methods: In this descriptive cross-sectional study, a total of 121 pathologically confirmed esophageal or gastric cancers, with rural place of residence, were retrieved from the cancer registry at the health department in Gorgan. After conducting interview with patients or their relatives, analysis of their sociodemographic and clinicopathologic features was performed. The median survival rate was compared regarding age groups and gender using Kaplan-Meier statistical test. Results: Male to female ratio in esophageal and gastric group were 1.2 to 1 and 3.8 to 1, respectively. Short-term survival rates were 54.76% and 26.2% for esophageal cancer and 66.6% and 37.5% for gastric cancer. Collected information regarding patients’ sociodemographic and clinicophathologic factors did not have significant association with patients’ survival in both esophageal and gastric cancers. The mean survival rate in patient with gastric and esophageal cancers according to age and gender was not significant. Conclusion: This study showed that the overall short-term survival rates for upper gastrointestinal cancers are very low in Golestan province. Therefore the need for intervention the need and allocating more diagnosis and therapeutic resources for upper gastrointestinal cancers are required.
Shahryar Semnani (md), Gholamreza Roshandel (md), Abbasali Keshtkar(phd), Laily Najafi (md), Taghi Amiriani (md), Mehran Farajollahi (md), Abdolvahab Moradi (phd), Hamidreza Joshaghani (phd), Amirhossein Noohi (md), Nafiseh Abdolahi (md),
Volume 11, Issue 1 (3-2009)
Abstract

Background and Objective: Stress has been known as an important causative factor in irritable bowel syndrome. Various studies have indicated the relationship between serum leptin levels and stress levels. This study was undertaken to investigate the relationship between serum leptin levels with irritable bowel syndrome. Materials and Methods: In This case-control study, eighty irritable bowel syndrome patients and 80 controls were recruited. All participants were asked to fill in a questionnaire included demographic information and medical history as well as a stress questionnaire. Serum leptin level was measured by ELISA method. Chi-square, student t-test, pearson correlation and logistic regression were used for investigating the relationships between variables. Results: Participants in irritable bowel syndrome group had significantly higher stress levels than controls (p<0.05). In the other hand, Serum leptin levels were significantly lower in irritable bowel syndrome group than the other one (p<0.05). Multivariate logistic regression analysis showed that after adjustment of stress level and body mass index, serum leptin level was still significantly lower in irritable bowel syndrome group (Odds ratio=0.9 CI95%:0.85-0.94). Conclusion: The present study indicated that there is a relationship between leptin and irritable bowel syndrome and serum leptin level is significantly lower in irritable bowel syndrome group than controls. This relationship is independent of other variables such as stress levels, BMI.
Abbas Ali Keshtkar (phd), Shahryar Semnani (md), Gholamreza Roshandel (md), Maryam Aboomardani (phd), Nafiseh Abdolahi (md), Sima Besharat (md), Abdolvahab Moradi (phd), Khodaberdi Kalavi (msc), Saba Besharat (bsc), Honeyeh Sadat Mirkarimi,
Volume 11, Issue 2 (7-2009)
Abstract

Background and Objective: Colorectal cancer is the third common malignancy in the world. Personal habits including life style and nutrition have been proposed as risk factors of colorectal cancer. We conducted this study to assess the nutritional characteristics in colorectal cancer patients in Golestan province of Iran.

Materials and Methods: This case-control study was done on 47 colorectal cancer cases, diagnosed during 2004-05 and 47 healthy controls. A questionnaire containing socio-demographic and nutritional characteristics (FFQ) was filled for each of the participants. Chi square test was used to assess the relationship between variables.

Results: In each of the two groups, 40.4% were females and 59.6% were males. The mean±SD age of age in cases and controls were 52.4±13.4 and 52.1±13.1 years, respectively. Total energy expenditure of higher than 1837.5 Kcal/ day was significantly related to colorectal cancer (OR=3.8 95% CI: 1.2-11.3). Colorectal cancer risk was higher in individual with frying cooking method (OR=3 95% CI: 0. 8-11.1). The risk of colorectal cancer was 6.5 times higher in individuals with fat consumption of higher than 118.5 grams/day (95% CI: 1.5-28.8). No significant relationship was seen between vegetables consumption and the risk of colorectal cancer.

Conclusion: This study showed that high total energy expenditure, high fat consumption and using frying method for cooking are risk factors of colorectal cancer in Golestan prevince in Nothern of Iran.


Shahryar Semnani (md), Sima Besharat (md), Ali Arabali (md), Abbasali Kestkar (md, Phd), Gholamreza Roshandel (md), Nafiseh Abdolahi (md), Naser Behnampour (msc),
Volume 11, Issue 3 (10-2009)
Abstract

Background and Objective: Esophageal and gastric cancers are among the most prevalent cancers in the world which cause a high mortality rate annually. Several risk factors are supposed for them. Water hardness is considered as a protective factor against above cancers. This ecologic study was designed to determine the correlation between water hardness and upper gastrointestinal cancers. Materials and Methods: In this ecological study data on water components in Golestan's urban areas were obtained during 2004-05 and the averages were reported. All cases of esophageal and gastric cancers resided in urban areas which were diagnosed during this period were recruited to estimate the incidence and age standardized rates (ASR). The province was divided into low, intermediate and high incidence, based on 33% and 66% quartiles of both cancers. Pearson correlation coefficient test and regression model were used to analyze the data. Results: The water hardness was in the normal standard range permitted for the drinking water, and did not have any relation with the risk of esophageal and gastric cancers. Conclusion: This study showed that water hardness has no effect on the incidence of esophageal and gastric cancer in this area.
Semnani Sh (md), Roshandel Gh (md), Keshtkar Aa (phd), Zendehbad A (md), Rahimzadeh H (msc), Besharat S (md), Abdolahi N (md), Moradi A (phd), Sarikhani Aj (hnd), , ,
Volume 12, Issue 3 (10-2010)
Abstract

Background and Objective: Golestan province, located in north of Iran has been known as a high risk area for esophageal cancer. The relationship between esophageal cancer and Selenium (Se) has been assessed in previous studies. This study was conducted to assess the relationship between Soil selenium levels and development of esophageal cancer in Golestan province of Iran. Materials and Methods: In this ecologic study, Golestan province in northern Iran was divided into 135 blocks based on geographical altitude and longitude on the map. One Soil sample was collected from the center of each block. Selenium level in Soil samples was determined by flame atomic absorption spectrometry. Statistical analysis was performed by Pearson correlation and T-Student tests. Results: The mean±SD of Soil Selenium level in Golestan province was 3.7±1.61 mg/kg. There was a positive correlation between Soil level of Selenium and esophageal cancer rates in this area (P=0.03), (Pearson correlation coefficient=0.19). The Soil Selenium level for high risk and low risk area for esophageal cancer were (4.13 mg/kg) and (3.39 mg/kg) respectively (P=0.01). Conclusion: This study showed that there is high Soil Selenium level in Golestan province in north of Iran. Also it is found to be a significant positive relationship between Soil Selenium level and esophageal cancer rate in this area.
Motahari Mm (md), Abdolahian N (md), Besharat S (md),
Volume 13, Issue 4 (12-2011)
Abstract

Background and Objective: Floater is defined as dark and vague spots and lines, which presents in visual fields of patients. Etiologies are various and life threatening, due to the serious complications resulted from floaters, this study was designed to assess ophthalmic disorder among patients with floater Gorgan, Iran (2009). Materials and Methods: This cross-sectional study,was done on 164 patients (105 female, 59 male) with floater or photopsia in Gorgan, North of Iran during 2009. Findings of ophthalmic examination and demographic characteristics were recorded in a questionnaire for each patients. Results: The prevalency of floater was higher among patients over sixty years old. 57.2% women with floater were during monopausal period. Myopia (32.9%) and cataract (32.9%) were the most associated ophthalmic diseases. Posterior vitreous detachment and retinal bleeding in patients with floater was 84.1% and 6.1%, respectively. Retinal detachment was not seen in patients. Conclusion: This study showed that posterior retinal detachment is the most frequent associated ophthalmic disorder in patients with floater. Older age, gender, myopia and cataract are considered to be the related risk factors in floater.
Hakimjavadi M, Gholamali Lavasani M, Shakouri Hr, Abdolahifar A, Momeni F,
Volume 17, Issue 1 (3-2015)
Abstract

Background and Objective: Hyperactivity / attention deficit disorder (ADHD) with 3-5% is the most common disorder in children. This study was done to compare the efficacy of behavioral, medicinal and combination of behavioral and medicinal therapy on reduction of ADHD symptoms in children. Methods: This quasi-experimental study was carried out on 40 male elementary students with ADHD in Gorgan, Northern Iran during 2011-12. Subjects were divided into the four groups including control, behavioral, medicinal (Ritalin 10 mg three times per day) and combination of behavioral and medicinal therapy. Conner's Rating Scale for parents (home) and teachers (school) were used in pretest-posttest spot after 8 weeks therapy. Results: After intervention ADHD symptoms significantly reduced in behavioral, medicinal and combination of behavioral and medicinal therapy in compared to controls (P<0.05), but this reduction was more in medicinal and combination of behavioral and medicinal therapy groups than behavioral group. Conclusion: Medicinal and combination of behavioral and medicinal therapy has the same efficacy in reducing ADHD symptoms in children.
Yousef Khanjari , Alijan Tabarraei , Morteza Oladnabi, Nafiseh Abdolahi ,
Volume 20, Issue 1 (3-2018)
Abstract

Background and Objective: Single Nucleotide Polymorphisms in programmed cell death which expressed at high level in T cells, plays an important role in the development and cause autoimmune disorders. This study was done to evaluate the frequncy of rs11568821 polymorphism in patients with systemic lupus erythematosus (SLE).
Methods: This case-control study was done on 76 patients with SLE and 56 healthy controls. After DNA extraction, frequncy of polymorphisms PDCD1.3 by polymerase chain reaction and sequencing methods in subjects were determined.
Results: There was a significant diference between frequency of allele and genotype at rs11568821 Polymorphism in region of intron 4 of PDCD1.3 gene in case and control groups (P<0.05). A allele and AG genotype was significantly higher in patients than healthy controls (9.5% vs 0.09%, P<0.05). There was no significant association between clinical and laboratory findings with genotype frequencies.
Conclusion: rs11568821 single nucleotide polymorphism in intron 4 gene region PDCD1 can be used as a genetic factor to be involved the SLE susceptibility.
Navid Rahimi, Nafiseh Abdolahi , Sima Sedighi , Mehrdad Aghae , Atefeh Rezaeifar ,
Volume 20, Issue 3 (10-2018)
Abstract

Background and Objective: Systemic lupus erythatous (SLE) is an autoimmune disease with clinical symptoms. Anti neutrophil cytoplasmic antibody (ANCA) is common in vasculitis which is reported in SLE. This study was done to determine the frequency of ANCA in patient with SLE and its association with disease activity.
Methods: This descriotive study was conducted on 80 patients with SLE whom referred to rheumatology clinic in Gorgan, northern Iran during 2012-15. The patients disorder diagnosed based on the ACR Criteria. According to the disease activity the patients divided to active group and inactive group. Demographic data was completed with questionnaire and blood sample collected in order to evaluate of for serum ANCA by using ELISA method.
Results: The average age was 37.5±12.4 year. Seven (8.5%) patients were males. 91.5% of patients was females. 27 patients (33%) had active lupus and 53 (57%) had inactive lupus. Only one patient has been reported as positive for ANCA. The patient was a 45 years woman with history of 10 years of lupus nephritis with active disease.
Conclusion: There was no relationship between ANCA and disease activity. The main reason for this finding can be a few numbers of positive cases in this study.
Alireza Norouzi , Afshin Sardarzade Majd, Behzad Vatankhah , Nafiseh Abdolahi , Samaneh Tavassoli , Abdolreza Fazel , Asieh Khalili , Somayeh Pasandi , Saba Besharat ,
Volume 22, Issue 2 (6-2020)
Abstract

In December 2019, the new acute respiratory disease spread in China presented with fever and dry cough known to be resulted from the new Corona Virus as the COVID-19. In Iran, the first case was reported on 20th of February 2020. Our management team in Golestan University of Medical Sciences held an immediate meeting to decide how to manage the cases suspected to the COVID-19.The two main hospitals had been selected as the Corona center in the Golestan province, northern Iran. Admitting patients other than COVID-19 has been stopped in these hospitals, and all patients had been transferred to the other hospital in Gorgan city and those in the recovery state had been transferred to a hotel prepared for this purpose. The capacity of Sayyad-e-Shirazi hospital was 300 bed for admission and 25 ICU beds that had been increased to 44 ICU beds (30 percent increases) to be prepared for COVID-19 admission. Clinical groups and specialists had been organized with special duty for each part. After 3 months of COVID-19 crisis, Sayyad-e-Shirazi hospital with 300 beds is in a good shape and admission of severe cases has been decreased.

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مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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