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Showing 82 results for Type of Study: Short Communication
Ali Ahmadi (msc), Ghodratollah Yosefi (bsc),
Volume 10, Issue 2 (6-2008)
Abstract
Background and Objective: Depression is the most common mood disorder. To assess the incidence and wide spread of depression and associated factor among of Bakhteyari tribal as native population in Chaharmahal and Bahkteyari province, this study was conducted. Materials & Methods: This study was a descriptive and cross-sectional study which was carried out on 400 subjects by using a systematic random sample technique during 2006. Depression was assessed by Beck inventory depressive questionnaire. Data was Analyzed by SPSS-11 Software and t-test , Chi-Square , ANOVA. Results: Mean±SD of depression score in female and male were 18.5±10.8 and 14.9±11.45, respectivly. Depression incidence rate in population was 29.6% (CI 95%: 25.6-33.6). Intermediate and upper degree of depression prevalence was determined to be 24%. The incidence rate of descriptive in female was higher than males (P<0.05). There was a significant relationship between depression in house wife and jobless people (p<0.05). The highest incidence rate was either under 20 years or above 50 years old. Conclusion: This study showed that the depresion rate is higher among the tribe than in other groups in this province.
Ali Shahryari (msc), Mohammad Javad Kabir (msc), Kolsoom Golfirozy (bs),
Volume 10, Issue 2 (6-2008)
Abstract
Background & Objective: Gorgan Gulf, with unique environmental value, has been located at the eastern south region of the Caspian Sea. It has not only valuable fish species such as strugen, Caspian roach, carp and vobla fish which supply a great part of daily protein need of our country and the world, but also its beaches are used for swimming. Therefore Lack of observation for environmental regulations result in entrance of microbial pollutants into Gorgan Gulf and creates dangers both for human health and for marine environment. So the evaluation microbial pollution for these beaches and comparing them with standards is an essential need. This study was done to evaluate microbial pollution for Caspian Sea at Gorgan Gulf. Materials & Methods: 40 sea water samples were collected during spring and autumn of 2004 at Gorgan Gulf for evaluation of sea water in Gorgan Gulf microbial pollution and also the mean total number of bacteria, coliforms, fecal coli forms and fecal streptococci was determined by standard method. Results: The results indicated that the mean total number of bacteria, coli forms, fecal coli forms and fecal streptococcus were 5001/1cc, 1555/100cc, 817/100cc and 59/100cc respectively. Conclusion: Mean results compared with related standard (both for swimming beach and piscicultres) and we found that Gorgan Gulf beaches have been polluted for swimming applications, but it is not the case for piscicultures.
Mohammad Reza Motie (md), Naser Behnampour (msc), Hamid Alinezhad (md),
Volume 10, Issue 4 (12-2008)
Abstract
Background & Objective: Trauma is the second most common cause of death regardless of age in Iran and the health system annually defrays a vast cost for trauma patients. The majority of cases comprise abdominal trauma. This study was performed to determine individual and pathologic characteristics of patients with blunt abdominal trauma in Gorgan – Iran. Materials & Methods: This descriptive and retrospective study was done on 239 patients with blunt abdominal trauma in 5 Azar hospital, Gorgan - Iran from March 2001 to March 2005. Results: 197 (82.4%) of cases were male and 42 (17.6%) were female. The mean age of patients was 23.4 years. The mean of hospital stay was 8.8 days. The most common cause of blunt abdominal trauma was traffic injury. The most common damaged organs were spleen (49.4%) and liver (21.3%) respectivly. Mortality rate was 16.3%. The hypovolumic shock was the major cause of mortality. Conclusion: This study showed that epidemiology of trauma is similar to those in other regions of our country. Therefore, programming and attempts of governmental organizations are needed to prevent and decrease traffic accidents.
Morteza Mansourian (msc), Mahdi Kargar (msc), Naser Behnampoor (msc), Hadi Rahimzade (msc), Mostafa Ghorbani (msc),
Volume 10, Issue 4 (12-2008)
Abstract
Background and Objective: The compound of MDMA or 3,4methyl deoxy met amphetamine, so called ecstasy, is a new narcotice compound. Ecstasy tablets have a temporary exciting and deteriorating side effects. This study was done to determine the knowledge and attitude of University students about ecstasy tablets in Gorgan, Iran. Materials and Methods: This descriptive - analytic study was done on 300 university students in Gorgan during 2006. The tools of data collection were questionnaire. This questionnaire developed by authors, consists of demographic, knowledge and attitude questions respectively. The data were analized by SPSS software and Kruskal- Wallis and Mann- Whitney tests. Results: 3% of subjects had previous usage of ecstasy. The 27.3% of students had poor knowledge about ecstasy, also 52.3% and 12.7% of students had middle and high knowledge about ecstasy respectivly. There was significant relation between knowledge and attitude with educational level, family income, parents occupation and previous usage of ecstasy (P<0.05). But there was not any relation between knowledge and attitude and age, gender, and filed of education and source of information enquiry. There was a possitive correlation between knowledge and attitude of students (P<0.001, r=0.243). Conclusion: This study showed that knowledge and attitude of University students about ecstasy is low. Therefore educational programs about ecstasy is nessecery to increase the knowledge and attitude of university students.
Leili Chamani-Tabriz (md, Mph), Hojjat Zeraati (phd), Soheila Asgari (student of Msc), Soroor Asadi (md), Saeed Zarei (md),
Volume 10, Issue 4 (12-2008)
Abstract
Background and Objective: Genital herpes is increasing in Asia and the world. Based on other studies, knowledge has an important role in reducing high risk sexual behavior. In this study we evaluated knowledge among Shahid Beheshti University students as a sample of young and educated population of Iran. Materials and Methods: This cross-sectional study carried out on 409 of Shahid Beheshti University students in Tehran - Iran at Autumn 2004. Research material was questionnaire and data analyzed by SPSS-13, T-student, Chi-square, Mann-Whitney, Kruskal-Wallis Tests. Results: Mean±SD of level of knowledge, nature and transmission of genital herpes was 26.5±26%, 23.7±24.2% and 30.56±36.8%, respectively. The level of knowledge about signs, treatment and prevention of disease was 18.8%, 16.4% and 46.2%, respectively. There was a significant relation between age, marital status and education with knowledge (P<0.05). The level of knowledge among engineering students was higher than humman sciences students (P<0.05). Conclusion: Based on our study, most of participants had no enough knowledge about genital herpes. Most of participants were willing to know more about it as they obviously welcomed to our pamphlets. It seems that educations about genital herpes should be added to educational programs.
Seyed Mehran Hosseini (md, Phd), Ali Reza Maleki,
Volume 11, Issue 1 (3-2009)
Abstract
Background & Objective: Pulse pressure is a marker of arterial stiffness. In old age the pressure wave reflection also contribute to disparity of pulse pressure between upper and lower limbs. This study was done to determine the relation between ageing and increased pulse pressure of upper and lower limbs. Materials & Methods: In this discriptive study blood pressure measured in 40 nonsmoker men, all free from medication and disease history, insubjects divided in two groups: 18-25 and 50-70 years old with mean age of 22±1.3 and 59±2 years respectively. Using a mercury-column sphygmomanometer (ERKA) with appropriate cuff size and after five minutes of quiet rest, the blood pressure was determined in supine posture at three separate times. The lower limb pressure was measured with placing the cuff on calf muscle and the stethoscope on posterior surface of internal malleolus. The mean of the second and third records rounded and were used for analysis. Results: The right and left brachial and ankles pulse pressure in two groups were: 44.50±2.03, 44.50±1.71, 37.90±2.24, 37.25±2.30 mmHg in 18-25 years old group and 47.10±2.74, 46.90±2.65, 56.05±3.18, 55.90±4.48 mmHg in 50-70 years old group, respectively. Significant differences were found between brachial and ankle pulse pressure in both sides in first group, (P<0.05). In the second group this difference was only significant at right, (P<0.05). The ratio of brachial pulse pressure to ankle pulse pressure in 18-25 years old group was greater than 1 and in 50-70 years old group it was less than .15 In both side the ankles pulse pressure was significantly greater in 50-70 years old group (P<0.05). Conclusion: This study showed that in subjects of more than 55 years of age, the increasing of pulse pressure was more prominent in lower limb. The ankle pulse pressure may be a proper index of central pulse pressure changes and atherosclerosis of elastic arteries with ageing.
Arezoo Mirfazeli (md), Sima Besharat (md), Anahita Rashedi (md), Mohammad Reza Rabiee (msc),
Volume 11, Issue 1 (3-2009)
Abstract
Background & Objective: Health evaluation and growth monitoring of the infant is a visual diagram of growth and primary health services are based on it. In the best option, these indices must be provided separately for each community. This study was done to evaluate growth indices of newborns in Gorgan- Northern Iran. Materials & Methods: In this observational descriptive study which was carried out during (Oct-Nov 2003), all healthy infants without any major abnormality born within 25-42 weeks of gestational age were evaluated in Dezyani Hospital, Gorgan growth indices (head circumference, length and height) were measured in 1011 infants. Gestational age was defined by Balard scoring and delivery type was recorded, too. After entering data into SPSS-10 software, data were analyzed using chi-square, t-test and correlation bivariate. Results: Mean gestational age (±SD) was 39.86±1.72 weeks and most of them were born by vaginal delivery. Amongst them, 3.2% were premature (less than 37 weeks), 4.4% were low birth weight and 0.69% were very low birth weight. Correlation between growth indices and gestational age was significantly positive in all cases (p<0.05). Conclusion: This study showed that growth indices are lower than other parts of Iran. Further investigations needed, especially longitudinally and cross-sectional, to determine the growth indices in this region and in other parts of country.
Mohammad Dadypour (bsc), Rasool Salahi (md), Farzad Ghezelsofla (md),
Volume 11, Issue 1 (3-2009)
Abstract
Background and Objective: Animal biting is a very important threat for human health, due to the post-infections, such as rabies, which would be fatal. This Study was carried out to determine the epidemiological aspects of animal bites in Kalaleh district, North of Iran. Materials and Methods: In this descriptive and cross sectional study, all cases with animal biting during 2003-05 which were reffred to Kalaleh, Maraveh- tappeh therapy centers in Golestan province North of Iran were considered as sujects of this epidemiological survey. Results: From the totally 3496 biting, during 3 years, 2477 cases (70.9%) were male and 1019 (29.1%) female. The Mean age of cases was 24.2±17.5 and age domain between 1 to 86 was variable. The biting incidence rate was increased during 3 years, as follow 2003, 2004 and 2005 were 745/100000, 787/100000 and 788/100000 respectively. Total incidence was 773/10000 during the 3 years, the most biting frequency belong to the students 1157 (37%). Lower limb was the most common site of biting 2344 (67%). Dog was the common animal in biting 3344 (95.6). Most biting happened in spring season 1042 (29.8%). 3151 cases (90.1%) were living in rural area. 3198 cases (91.5%) and 298 (98.5%) had complete and uncompleted vaccination respectively. Conclusion: According to the results from this survey, the rate of dog biting in Kalaleh district was more than the other region, therefore, it would be important that all concerning organizations interfere to prevent and control this health threat.
Seyyed Mohammad Alavi (md), Arash Etemad (md), Mehrdad Azmi (md),
Volume 11, Issue 2 (7-2009)
Abstract
Background and Objective: There are some reports on the association between helicobacter pylori infection and typhoid fever in different parts of the world. The aim of this study was to estimate the co infection of helicobacter pylori and typhoid fever in Ahwaz city in South-West of Iran.
Materials and Methods: In this case – control study, fifty hospitalized patients with definite diagnosis of typhoid fever in Razi and Abuzar hospitals in Ahwaz were investigated. For each patient, one subject was matched with age, sex and socioeconomic characteristic as control. All of the case and control were tested for IgG –anti helicobacter pylori by ELISA method. Data were analyzed by chi squared test in SPSS software.
Results: Seroprevalence of helicobacter pylori in case (66%) was higher than control (44%) (p<0.05). There was a significant difference between patients and control in male (p<0.05), but not in female.
Conclusion: This study indicated that typhoid fever is associated with helicobacter pylori co-infection in this region.
Shahryar Semnani (md), Sima Besharat (md), Ali Arabali (md), Abbasali Kestkar (md, Phd), Gholamreza Roshandel (md), Nafiseh Abdolahi (md), Naser Behnampour (msc),
Volume 11, Issue 3 (10-2009)
Abstract
Background and Objective: Esophageal and gastric cancers are among the most prevalent cancers in the world which cause a high mortality rate annually. Several risk factors are supposed for them. Water hardness is considered as a protective factor against above cancers. This ecologic study was designed to determine the correlation between water hardness and upper gastrointestinal cancers. Materials and Methods: In this ecological study data on water components in Golestan's urban areas were obtained during 2004-05 and the averages were reported. All cases of esophageal and gastric cancers resided in urban areas which were diagnosed during this period were recruited to estimate the incidence and age standardized rates (ASR). The province was divided into low, intermediate and high incidence, based on 33% and 66% quartiles of both cancers. Pearson correlation coefficient test and regression model were used to analyze the data. Results: The water hardness was in the normal standard range permitted for the drinking water, and did not have any relation with the risk of esophageal and gastric cancers. Conclusion: This study showed that water hardness has no effect on the incidence of esophageal and gastric cancer in this area.
Aioub Sofizadeh (msc), Yavar Rassi (phd), Mohammad Reza Abbasi (msc), Mohammad Ali Oshaghi (phd), Rasool Salahi (md), Sina Rafizadeh (msc), Mehdi Mohebali (phd),
Volume 11, Issue 3 (10-2009)
Abstract
Background and Objective:leishmaniasis is a Zoonotic disease that is transmited by sandfly to human. This study were carried out in order to demonstrate some ecological characters of leishmaniasis vectors in Kalaleh district, Golestan province ,Iran, during 2006-07. Materials and Methods: In present study 6 villages were selected. Sandfly were collected by sticky traps. 3 places were sampled in each village and in each places 20 traps were installed. After sampling collection, we used diagnostic criteria to identify the Sandflies, also confirmed human cases were recorded according to the months of identification. Results: 4900 sandflies were detected in 6 villages and 12 species of sandflies were identified, which including P.papatasi, P.mongolensis, P.caucasicus, P.caucasicus group, P.sergenti, P.alexandri, P.kazeroni, P.brevis, P.(adlerius) sp, S.sintoni, S.clydei, S.sogdiana). P.papatasi was predominant species in indoor places (46.1%) and S.sintoni was in outdoor places (36.7%). Sandflies activities extended from early May through mid October with two peaks in mid June and September. Human infection had a important peak in January. During the collection of sandflies, the species of P.alexandri, P.kazeroni, P.brevis, P.(Adlerius sp.), S.clydei and S.sogdiana were collected for the first time from this area. Conclusion: In this study, P.papatasi was the predominant species in this area. Sandflies second activity peak occured in September that is crucial for transmission of disease. The incubation period for this disease was four months.
Besharat S (md), Besharat M, Akhavan Masouleh A (md), Jabbari A (md), Yazdi Hr (md),
Volume 12, Issue 1 (3-2010)
Abstract
Background and Objective: Opium usage for sedating/relieving from diarrhea or cough causes a public health problem. In the northeast of Iran (Golestan province), opium is used widely for symptomatic therapy of routine illnesses in young children. It may cause severe intoxication and even death. This study was done to determine the toxification with opium in five years old children in Golestan Privine in Iran. Materials and Methods: This cross-sectional study was performed in collaboration with “Adverse Drug Reaction (ADR) Committee” in Golestan University of Medical Sciences. All members of ADR committee in pediatric centers trained to complete a certain valid questionnaire in children under 5-years-old, which either referred or admitted for opium intoxication (September 2006 to February 2007). Data analyzed by Chi-square and Fisher exact tests. Results: In this survey, 67 opium-intoxicated children were recruited. Minimum age of the subjects was 6 days and maximum was 5-years-old. In 41.3% of subject. The opium was given by the mother with low awakness and 61.2% of in toxicated children reside with rural area. More that 80% of the parant had the educational level below. The highschool diploma in 63.6% of cases the pure form of opium were consumed, diarrehea anxiety, were the two main cause for consuming the opium. In this study four subjects decleard dead due to toxification of the opium. Conclusion: Opium intoxication has a high prevalence among children under 5-years-old in our area. Therefore it is suggested that the intoxicated children accompanied with parant ambigious explanation opium toxification should be taken seriously.
Alaedini F(phd), Khoddam H (msc), Kazemi Bajestani Mr (gp Mph), Koshan F (gp), Etemadi A (phd), Keshtkar Aa (phd),
Volume 12, Issue 2 (7-2010)
Abstract
Background and Objective: Quality of medical articles is effective at improvement of medical science. This study was done for determining of published medical articles quality in approved Medical Journals. Materials and Methods: This cross- sectional study was done on 690 medial articles, which published between 1983-2005 in scientific journals, approved by special Medical Journal committee of Ministry of health and medical Education (MOHME) in Iran, during 2007. Source of data was indexed medical journal in the Iranmedex database. Results: Type of study in 52% of articles was descriptive, 21.2% was interventional and 5.8% of them were analytical. In recent years the number of analytic and interventional articles have been increased significantly in comparison to other types (P<0.05). There was no qualitative type article in published papers. The percentages of original, case report and review articles were 44.9%, 36.9% and 14.1%, respectively. In recent years the rate of original articles has increased in comparison to case report and review articles (P<0.05). In 80% of articles, at least one statistical test was applied. 60% of articles were clinical and 82% of them have been written in Persian language. Conclusion: Findings showed an increasing trend in quality indexes of published articles. It seems in recent years, the changes of MOHME policies in evaluation of the research deputy of medical science universities implementation of research and scientific writing workshops ratting protocol of approved medical journals and academic members promotion guidelines, resulted in improvement qualitative index of articles.
Zahmatkesh H (md), Hajimoradloo N (md), Kazemi Malekmahmoodi Sh (bsc), Khoddam H (msc),
Volume 12, Issue 3 (10-2010)
Abstract
Background and Objective: Life saving with a high quality health care programs in the shortest duration is the mainstay of emergency department system. Frequent monitoring and quality control of this process and the satisfaction of patients are among the very important indices in hospital quality. This study was designed to evaluate the clients satisfaction in the hospitals affiliated to Golestan University of medical sciences. Materials and Methods: This descriptive cross-sectional study was done on 2400 referred patients in emergency departments of different hospitals in Golestan province, northern Iran during 2006. Data were gathered by questionnaire included demographic data and questions about satisfaction of outpatients and emergencies. The Data analyzed by SPSS-15 software and chi-square test. Results: Level of satisfaction in emergency department, was reported as follow: physician attention and behaviors (86%), nursing behaviors (85%) responsibility to patients (84.1%) status of the environmental temperature (83.9%) and cleaning (81.9%). The lowest satisfaction was related to behavior of guardsman (33.8%). In emergency ward, levels of patient's satisfaction were as following: Access to telephone (49.7%) quality of the meals (47.4%) quantity of meals (44.1%) and the lowest level of satisfaction of patient was neglecting the patient's right (8.2%). Conclusion: This study indicated that more educational programs, should be arranged for the emergency units employees to observe patients right.
Amani F (phd), Kazemnejad A (phd), Habibi R (phd), Hajizadeh E (phd),
Volume 12, Issue 4 (12-2010)
Abstract
Background and Objective: Mortality rate and causes of death is one of the main components in health planning at each society. This study was done to show the pattern of mortality trends in Iran during 1970-2009. Materials and Methods: In this cross-sectional descriptive study related data to 9740656 deaths registered in National Organization Civil Registration were surveyed and analyzed during 1970-2009. SPSS software and statistical descriptive methods were applied to evaluate the data. Results: 60.4% of all registered death was in rural areas. 61.1% were male. Crude death rate according the current statistics decreased from 13 per 1000 in 1970-75 to 5 per 1000 in 2005-09. Life expectancy with 28.6% increased from 55.2 years in 1970-75 to 71 years in 2005-09. Conclusion: This study showed that all mortality indicators in Iran were lower than other part of the world. There was a general decreasing in infant mortality rate in last three decade. Also the death registry system has been improved during study years.
Asayesh H (msc), Qorbani M (msc), Salary H (md), Mansorian M (msc), Safari R (bsc),
Volume 12, Issue 4 (12-2010)
Abstract
Background and Objective: Substance abuse is a major concern all over the world. Due to some individual, familial and social factors the identification of related factors can help us to design a more effective strategies for the prevention of drug abuse. This study was performed to evaluate the relation between individual and familial characteristics with substance abuse tendency in self-introduced addicts. Materials and Methods: This case control study was done on 120 addicted subjects referred to addiction clinic of 5Azar hospital, Gorgan, North of Iran and 120 matched non-addicted subjects were considared as controls. Data collections were performed by questionnaire and interview. Data analyzed with using T-test, Chi-Square and logistic regression. Results: Univariate analysis showed that high school (OR=4.63, 95%CI: 1.78-12.02) and high school graduate subjects (OR=15.5, 95%CI: 4.9-50) showed higher tendency toward addiction compared to university educated people. History of substance abuse in friends (OR=7.33, 95%CI: 4.09-13.13) and previous and present cigarette smoking (OR=12.35, 95%CI: 6.65-22.93) increased abuse tendency. Permanent employment decreased abuse tendency (OR=0.109, 95%CI: 0.05-0.22) compared to temporary job. Conclusion: This study showed that addicted friends, cigarette smoking, low level of education and temporary job increase drug abuse tendency.
Abdollahi Aa, Hosseini Sa, Behnampour N, Salehi A,
Volume 13, Issue 1 (3-2011)
Abstract
Background and Objective: Cardiovascular diseases is the first cause of mortality in developed and developing countries. This study was done to determine findings of coronary arteries angiography of subjects referring to Kosar angiography center in Golestan province, Iran.
Materials and Methods: In this descriptive study 5444 patients whome referred to the Kosar angiography center in Golestan province, Northern Iran undervent in this study during 2008-09. Gender, age, ethnicity, body mass index (BMI), cigarette smoking, opium, hypertension and coronary arteries angiography findings were completed for each subjects. Coronary arteries angiography was performed on 5400 of subjects. Data was analyzed by using SPSS-13, ANOVA, Chi-Square and Kruskal-Wallis tests.
Results: In this study 52% of subjects were men. 72% of patients were Native Fars. 49.5% of subjects were found to be illiterate. While 92.6% of clients did not reported any history of smoking, 22.5% of subjects were addicted to different opium. The mean BMI was 27.48 and 38.2% of clients reported a history of hypertension. Coronary arteries angiography was performed on 5400 of subjects. Coronary arteries disorders were determined in 3142 of subjects (58.8% males, 41.2% females). Left anterior descending, right coronary artery, circumflex and obtuse marginal were the most involved coronary arterial branches in positive angiograms, respectively.The most severe failure (47.7%) has been found in left anterior descending artery.
Conclusion: Due to high incidence of coronary arteries disease in this region of Iran, it is suggested to design a project to investigate the preventive mearsures of cardiovascular disorders.
Tajbakhsh R, Dehghan M, Azarhoush R, Sadani S, Kaboutari M, Qorbani M, Samadzadeh S,
Volume 13, Issue 1 (3-2011)
Abstract
Background and Objective: Mucocutaneons manifestations are common in hemodialysis patients.The aim of this study was evaluate the prcvalence of cutaneous and mucosal manifestations in end stage renal disease (ESRD) patients who are on the maintenance hemodialysis.
Materials and Methods: This cross sectional study was performed on 100 (51 males, 49 females) hemodialysis patients in 5 Azar hospital in Gorgan, North of Iran during 2009. Patients selected on randomly based an all of them completely examined by a deramatologist for any changes in skin, hair, nail and mucous membrane. If necessary biopsy perform and refer to a pathologist. Data analysed with SPSS-13, mann-whitney, t-test, Chi-Square and Fisher tests.
Results: The average age was 49±12.3 years. The most common causes of ESRD was dibetes mellitus. The most common skin lesion was xerosis (78.3%), after that pruritis (39.1%) lentigo (34.8%) skin discoloration (32.6%) leukonychia (32%) thining of nail bed (24%) were common lesions. Lentigo was more common in female than male 42.85% vs 21.50% (p=0.042). Xerosis (p<0.01), scaling (p=0.042), lentigo (p<0.01), folliculitis (p<0.01), idio pathic guttate hypopigmentation (p<0.01) leukonychia (p<0.01) and half and half nail (p<0.01) have meaningful correlation with age. There was also meaningful correlation between dialyis duration and skin discoloration (p<0.031) and leukonychia (p<0.041). Clubhing and ca-p product also have meaningful correlation (p<0.027). Pruritis (p<0.048) and skin fungal infection (p<0.047) (tinea versi color) also have meaningful correlation with serum ferritin level.
Conclusion: Mucocutaneous manifestation were common in end stage renal disease patients.
Ravarian M, Sadeghian Mh, Ebrahimzadeh S, Daneshvar D,
Volume 13, Issue 1 (3-2011)
Abstract
Background and Objective: There are some reports about probable association between acute leukemia and special blood groups. Frequency of ABO and RH blood group is different in each population. This study was done to determine frequency of ABO and Rh blood groups in patient with acute leukemia and healthy population.
Materials and Methods: This case - control study was done on 214 patients (132 males, 82 females) that suffering from acute leukemia as case group and 117026 individuals healthy population who were voluntary blood donors as controls in Mashhad, Iran during 2001-07. Age, sex, ABO blood group and RH blood group were collected from hospital files for each cases. Furthermore the results of ABO and RH blood groups of controls were collected. Data were analyzed with Chi-Square, fisher test and Odd’s ratio.
Results: The frequency of A, B, AB, O and RH blood groups in cases were 23.8%, 32.8%, 7.0%, 36.4% and 90.7%, respectively. The frequency of A, B, AB, O and RH blood groups in controls were 29.8%, 27.4%, 8.9%, 33.9% and 88.3%, respectively. Odds Ratio test didn’t show association of ABO and RH blood groups with acute leukemia. Odds Ratio test showed association of B blood group with acute leukemia in females (OR=0.571, 95%CI: 0.358-.0908, P=0.021).
Conclusion: This study showed although there was not any association between ABO and RH blood groups and acute leukemia but probably females with B blood group are more susciptible toward acute lymphoblastic leukemia.
Amiriani T, Besharat S, Semnani Sh, Joshaghani Hr, Roshandel Ghr, Keshtkar Aa, Kiaii Mr, Mirkarimi Hs, Hashemi-Nasab Sz, Zendeh-Bad As,
Volume 13, Issue 1 (3-2011)
Abstract
Background and Objective: Celiac is a hereditary disease presented with chronic inflammation of small intestine. Several studies supposed a relationship between Celiac disease and Inflammatory Bowel Disease (IBD). Tissue trans-glutaminase antibody is one of the best serological markers in Celiac disease. This study was designed to evaluate the association of Celiac and IBD using tissue trans-glutaminase antibody.
Materials and Methods: In this descriptive study 127 confirmed IBD patients who were referred by gastroentrologists 2005-08 enrolled into the study. A questionnaire was completed and tissue trans-glutaminase antibody was evaluated with ELISA method with a Cut-off=12 U/ml.
Results: Among 127 referred patients, serum samples of 102 patients were collected. Mean±SD of age was 36.17±15.2 years and 48% were males. Ulcerative colitis, Crohn’s disease and other colitis were observed in 76 (74.5%), 7 (6.9%) and 19 (18.6%) of patients, respectively. Tissue trans-glutaminase antibody was positive (19.8 U/L) in one 46-years-old male patient with ulcerative colitis.
Conclusion: Tissue trans-glutaminase antibody titer was not significantly different between IBD patients and controls, thus it seems not appropriate to suggest as one of the routine tests in IBD patients.
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