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Background and Objective: Vitamin deficiency is common in patients with chronic low back pain and is one of the most important risk factors for chronic kidney disease. The aim of this study was to evaluate the effect of one course of core stabilization exercise and vitamin D intake on some of renal function biomarkers in patients with chronic back pain.
Methods: This single-blind clinical trial study was done on 48 women with chronic low back pain with random assignment in 4 groups of 12 people including control, exercise, vitamin D and combined groups. The exercise and combined groups performed 8 weeks of core stabilizing exercises with different levels. The vitamin D and combined groups received 50,000 IU vitamin D/week. Creatinine, urea and uric acid levels were measured before and after the interventions.
Results: The results showed that 74.26% and 25.64% of the patients had deficiency and insufficiency of vitamin D, respectively. After 8 weeks, significant reduction was observed in creatinine, urea and uric acid indicators of the exercise, vitamin D and combined groups (P˂0.05). In addition, combined intervention induced more reduction in mean of urea, and uric acid levels in compared to the two other interventions but the effect of exercise on the reduction of uric acid was more than vitamin D intake (P˂0.05).
Conclusion: Both core stabilization exercises and vitamin D intake intervention can be effective in improving renal function in chronic low back pain patients having abnormal low vitamin D levels. On the other hand the combined intervention seems to have more effectiveness.