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Background and Objective: Onosma dichroanthum Boiss. is one of the most important mountainous medicinal plants in Iran. This study was done to determine the biomechanical evaluation of root extract ointment of Onosma dichroanthum Boiss. on wound healing in rats. Materials and Methods: In this experimental study, 18 male adult Wistar rats were randomly allocated into control (I), vehicle (II) and treated group with ointment containing of extract 1% of root of Onosma dichroanthum Boiss., (III). 20 mm vertical skin incision wound were made on rats back side. The assessment of the wound healing was carried out at day 14. At the end of study, rats were sacrificed, skin sample were extracted and evaluated by biomechanical method (maximum force, elastic stiffness, energy absorption). Results: There was no significant difference in biomechanical parameters among the treated, vehicle and control groups. Conclusion: Topical application of Onosma dichroanthum Boiss. root have no effect on healing of skin wound in animal model.

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Background and Objective: Musculoskeletal disorder is a professional disease which is due to undesirable work condition and is a disturbing factor of health and welfare in societies. This study was carried out to determine the prevalence of musculoskeletal disorders in nurses and its relationship with the knowledge of ergonomic and environmental factors in north of Iran. Methods: This descriptive-analytic study was carried out on 110 nursing staff in Razi and Imam Khomeini hospitals in north of Iran. Questionnaire of the rate of awareness measurement, general questionnaire of musculoskeletal diseases (Nordik), the questionnaires of the health status and the study relationships between some factors in work place were filled out for each nurse. Results: Prevalence of the pain in neck, back, low back, shoulder, knee, thing pain, arm, leg among nurses was 50%, 49%, 58%, 44.9%, 47.3%, 32.7%, 36.4% and 56.4%, respectively. The condition of work place including air filtration (23.6%), light (22.7%) and air condition (4.5%) was not well. Chair (31%) and work table (34%) for work condition and body position of nurses was unsuitable. There was a significant relationship between low back pain and age and time of working per week of nurses (P<0.05). Nurses knowledge in the filed ergonomy was 77% and 22.2% of nurses trained in body condition during work. 60% of nurses were not trained for correct patient transportation and relocation. Conclusion: Nurses suffered more from pain in low back, knee, neck and legs. Training of nurses for patient transportation and body position during working in hospital is essential.

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Background and Objective: Flax seed has been shown to play a role in the prevention and treatment of dislipidemia and inflammation, which may enhance the benefits of training. This study was done to determine the effect of 10 weeks of aerobic training with flax seed supplementation on blood lipids profile and C-reactive protein in obese women.

Methods: In this clinical trail study, 45 obese middle-age women were randomly divided into 3 groups. Aerobic training program was performed 50-60 min/d, 3d/wk, for 10 weeks. Subjects in aerobic training with flax seed supplementation were received 6-9 garms, daily of flax seed. Body composition and metabolic parameters were assessed before and after the training period.

Results: Flax seed supplementation significantly improved triglyceride, HDL-cholesterol TC/HDL, body weight, body mass index, waist circumference and fat mass (P<0.05). Flax seed supplementation in combination  with aerobic training significantly improved adiposity indices body weight,body mass index, waist circumference , fat mass, triglyceride, HDL- cholesterol, LDL- cholesterol, LDL/HDL and TC/HDL (P<0.05).

Conclusion: Flax seed is safe and effective for improvement of cardiometabolic health in obse women and combination of flax seed can enhance beneficial effect of training over a ten-week period.

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Background and Objective: Increased ferritin levels have been implicated in the pathogenesis of diabetes. This study was done to determine the effect of continuous and interval aerobic exercise training on serum ferritin and iron level of induced diabetic rats.
Methods: In this experimental study, 32 wistar rats weighing 205±54 g were randomly allocated into four groups including healthy control, diabetic control, diabetic interval training and diabetic continuous training. The diabetic training groups were received 10 weeks of training following one week after the induction of diabetes by streptozotocin and nicotinamide. Fasting blood sugar ferritin and iron level was measured in each animal.
Results: Induction of diabetes significantly increased serum ferritin and iron levels in diabetic control group compared to healthy control group (P<0.05). Serum ferritin and iron levels and fasting blood sugar significantly reduced in interval aerobic exercise and continuous aerobic training groups compared to diabetic control group (P<0.05). There was not any significant difference in the dependent variables between interval aerobic exercise and continuous aerobic training.
Conclusion: In conclusion, it seems the training of two methods of aerobic interval and continuous training in induced diabetic rats with reduction of serum ferritin and iron levels, as well as improving fasting blood glucose and serum insulin seems to reduce insulin resistance index and improve glycemic status in induced diabetic rats.