---

Background and Objective: Diabetes mellitus is one of the most common serious metabolic disorders. This study was done to determine the effect of 12-week yoga intervention on glucose, insulin and triglyceride serum levels in women with type II diabetes mellitus. Materials and Methods: In this clinical trial, 26 women with Type II diabetes were divided into interventional (n=16) and control groups (n=10). Program of yoga exercise including: 75 minutes daily, three sessions in a week, and for 12 weeks. The level of glucose, insulin, leptin, HDL-C, LDL-C, triglyceride, total cholesterol were measured prior and post - training period. Results: The levels of glucose, insulin and triglycerides in the interventional group significantly reduced compared to control group following the training period (P<0.05). The level of leptin, HDL-C, LDL-C, total cholesterol was not significantly altered in intervention group in compare to controls. Conclusion: 12 weeks of yoga exercises can improve blood glucose, insulin and triglyceride in women with type II diabetes.