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Showing 11 results for Haghani H
Joshaghani Hr, Semnani Sh, Mirrezaee A, Abdolahi N, Besharat S, Behnampour N, Dehbashi Gh, Roshandel Gh,
Volume 8, Issue 3 (10-2006)
Abstract
Background&Objective: Celiac is a digestive disease. In this disease, small bowel is damaged and the absorption of nutrients are adversely affected. These patients do not absorb gluten. There is probably a correlation between esophagus cancer and celiac. The aim of this research was to study the seroepidemiology celiac disease in this area with high prevalency of esophagus cancer. Materials&Methods: This research was a descriptive study, which was performed on blood donors in Golestan province during the year 2005-06. blood samples were taken from 2547 subjects. tTG-IgA determination were carried out using ElISA technique, the titre<4U/ml, 4-10U/ml and >10Um/l were considered to be as negative, weakly positive and positive respectively. EMA antibody assessment were carried out on all sample population with more than 4U/ml, using IFA method. Results: 28 subjects (1.1%) had tTG-Ab positive test, out of this number 18 subjects (0.7%) were weakly positive and 10 persons (0.4%) were considered to be positive. EMA test were positive in 70% of subjects with tTG positive results. There was not any significant meaning between positive tTG test and ethnicity from weakly positive tTG, 15 subjects (83.3%) and 3 subjects (16.7%) were male and female respectively. The entire tTG positive were male subjects. Conclusion: In regard to high prevalency of esophagus cancer in the region and the relation of celiac disease with above cancer, it seems necessary to look more seriously at the celiac disease.
Joshaghani Hr, Ahmadi Ar, Behnampour N,
Volume 8, Issue 4 (12-2006)
Abstract
Background&Objective: Two enzymes have the ability to hydrolyze acetylcholine. One is acetylcholinesterase, which is called true cholinesterase, it is found in erythrocytes. The other cholinesterase is pseudocholinesterase, it is found in serum. Some chemical components of organophosphates group and carbamates affected cholinesterase activity. Determination of cholinesterase has application in diagnosis of liver disease, liver damage by insecticide and assessment of fatty liver. Pesticide factory workers are one group of peoples which are exposed of poisoning by pesticide. Materials&Methods: This research in 2005 performed in pesticide producers. In two stages (3 month interval) from 58 of personal blood was drown. Results: Mean of erythrocyte cholinesterase in first stage was 48.5±11.2 IU/gHb and second stage was 37.9±17.3 IU/gHb. Decrease of erythrocyte cholinesterase was significant differences (paired t test, P<0.05). Increase of serum AST was not statistically significant. Increase of serum ALT and Albumin was significant differences (paired t test, p<0.05). In 15 individual (25.9 %) cholinesterase decrease more than 35% and in 16 workers (27.6 %) erythrocyte cholinesterase decrease between 26-35%. Conclusion: Since in more than 26% of personnel cholinesterase decreased over than 35%, routine assessment of cholinesterase in similar factory, is recommended.
Hosseini Ss (bsc), Roudbar Mohammadi Sh (phd), Joshaghani Hr (phd), Eskandari M (msc),
Volume 12, Issue 4 (12-2010)
Abstract
Background and Objective: The Candida albicans is an opportunistic fungi that can be pathogenic in patients suffering from diabetes and AIDS. This organism can cause various infections such as superficial of the skin and mucosa to deep tissue infections. In this study the antifungal effects of ZnO and SDS on Candida albicans in comparison with Fluconazole were investigated. Materials and Methods: This was an experimental study which evaluated the antifungal effects of biocide SDS and ZnO on Candida albicans by microbroth dilution assay in broth and agar medium. Minimum Inhibitory Concentration (MIC) was determinated for each inhibitor during colony count in comparison with control. Results: MIC of ZnO was 1.013-296 µg/ml and for SDS and Fluconazole were 0.001-0.56 and 0.062-128 µg/ml respectively. Conclusion: This study demonstrated antifungal activity of ZnO can be a candidates for the elimination of candida in medicine particular in medical instruments.
Amiriani T, Besharat S, Semnani Sh, Joshaghani Hr, Roshandel Ghr, Keshtkar Aa, Kiaii Mr, Mirkarimi Hs, Hashemi-Nasab Sz, Zendeh-Bad As,
Volume 13, Issue 1 (3-2011)
Abstract
Background and Objective: Celiac is a hereditary disease presented with chronic inflammation of small intestine. Several studies supposed a relationship between Celiac disease and Inflammatory Bowel Disease (IBD). Tissue trans-glutaminase antibody is one of the best serological markers in Celiac disease. This study was designed to evaluate the association of Celiac and IBD using tissue trans-glutaminase antibody.
Materials and Methods: In this descriptive study 127 confirmed IBD patients who were referred by gastroentrologists 2005-08 enrolled into the study. A questionnaire was completed and tissue trans-glutaminase antibody was evaluated with ELISA method with a Cut-off=12 U/ml.
Results: Among 127 referred patients, serum samples of 102 patients were collected. Mean±SD of age was 36.17±15.2 years and 48% were males. Ulcerative colitis, Crohn’s disease and other colitis were observed in 76 (74.5%), 7 (6.9%) and 19 (18.6%) of patients, respectively. Tissue trans-glutaminase antibody was positive (19.8 U/L) in one 46-years-old male patient with ulcerative colitis.
Conclusion: Tissue trans-glutaminase antibody titer was not significantly different between IBD patients and controls, thus it seems not appropriate to suggest as one of the routine tests in IBD patients.
Taavoni S (msc), Soltanipour F (msc), Haghani H (msc), Ansarin H (md), Khayrkhah M (msc),
Volume 13, Issue 2 (7-2011)
Abstract
Background and Objective: Striae gravidarum is one of the cutaneous physiological changes during pregnancy with a high prevalence. This study was done to evaluate the effect of olive oil on prevention of striae gravidarum.
Materials and Methods: In a randomized controlled clinical trial, 100 nulliparous women referring to Tehran health ceatens were gone under investigation during 2009. Those whome had the inclusion criteria were divided to experimental group (using olive oil) and control group. The questionnaire was completed via interview and observation. Data were analyzed using descriptive statistics and Chi-Square test.
Results: Moderate striae gravidarum was seen 32% and 22% in intervention and conrtol groups, respectively. Severe striae gravidarum was 6% and 14% in intervention and control groups, respectively, but this diference was not significant.
Conclusion: This study showed that olive oil did not demonstrate to have any role in reducing of stria gravidarum.
Veghari Ghr (msc), Joshaghani Hr (phd), Hoseini Sa (md), Sedaghat Sm (md), Niknezhad F (msc), Angizeh Ah (bsc), Tazik E (bsc), Moharloei P (md), Salehi A (md),
Volume 13, Issue 2 (7-2011)
Abstract
Background and Objective: Hypertension is considered as a major public health problem in most countries due to its association with ischemic heart disease. The aim of this study was to determine people awareness of hypertension in Golestan province of Northern Iran.
Materials and Methods: This cross sectional population based study carried out on 2497 subjects (15-65 years old) including 1500 men and 1247 women in Golestan province- Northern Iran during 2006. The subjects were chosen by proportional-cluster sampling based on sex and age groups. The subjects were interviewed, antropometric indexes and serum biochemical factors were evaluated. Blood pressure was measured three times with 5 minutes interval and defined based on JNC-7 classification. Serum cholesterol and fast blood sugar (FBS) were determined using laboratory kits (enzymatic methods), and spectrophotometery technique. Data was analyzed by SPSS-16 software and Chi-Square test.
Results: In general, the prevalence of hypertension in this region was 23.9%. with higher rate among women urban area by 3.3% and 5% respectively. Only 48.7% of hypertensive patients were aware of their disease and that was significantly more in women than men (P<0.001). Low physical activity, chronical age, diabetes, hypercholesterolemia, general obesity, central obesity and illiteracy were the risk factor for hypertension morbidity (P<0.05).
Conclusion: This study showed, in spite of prevalency of hypertension among 20% of subjects in this area only 48.7% of them were aware about their disorder.
Bakhashandenosrat S (md), Mohammadian F (md), Ghaemi E (phd), Borghei A (md), Joshaghani Hr (phd),
Volume 13, Issue 2 (7-2011)
Abstract
Background and Objective: Menstrual disorders are including of metruragy, oligomenorrhea, polymenorrhea, dysmenorrheal and amenorrhea. Hormonal disorders can be the cause of such abnormalities. This study was designed to evaluate, the correlation between serum thyroid and sex hormones level,with menstrual disorders.
Materials and Methods: This descriptive - analytical study carried out on 110 women with menstrual disorders without anatomical disorders referred to private clinic during 2007-08. In third day of menstrual cycle, sample blood was taken for determination of LH, FSH, PRL, TSH, T3, T4 and Testosterone. Laboratory tests were performed by ELISA method.
Results: The 42.7% of women with menstrual disorders were in age group lower than 25 years. Oligomenorrhea with 42.7% was the major menstrual disorder and amenorrhea was the lowest with 4.5%. The most hormonal disorders was related to T3 (46.3%), LH (44.5%) and testosterone was the lowest with 5.4%. 11 cases (10.0%) have presented with hirsutism.
Conclusion: According to findings of this study T3 and LH are the common hormonal disorders in menstrual abnormalities.
Aboomardani M (phd), Rashidi Mr (phd), Rafraf M (phd), Arefhosseini Sr (phd), Keshtkar Aa (phd), Joshaghani Hr (phd),
Volume 13, Issue 4 (12-2011)
Abstract
Background and Objective: In pathogenesis of beta major thalassemia, tissue damage is occurring due to oxidative stress. The present study was designed to evaluate the effects of vitamin E supplementation on serum Paraoxonase, SOD, GPX enzyme activity and lipid profiles in beta major thalassemia patients. Materials and Methods: In this clinical tiral study, Sixty (25 males, 35 females) beta major thalassemia patients with age≥18 years who had criterias to enter the study, were selected randomely in two groups. The patients in interventional group, vitamin E at a dose of 400 mg/day were given for three months, with no supplementations in control group. The enzyme activities of paraoxonase, SOD, GPX and lipid profiles (LDL-c, HDL-c, triglyceride, total Antixidant Capacity) were measured prior and after 3 months in both case and control groups. Data analyzed by using paired t-test. Results: Significant increases in serum levels of vitamin E, Paraoxonase activity, HDL cholesterol (P<0.001), BMI (P≤0.001) and a significant reduction in GPX activity (P<0.05) were observed in cases compared to controls. Conclusion: The vitamin E supplementation may be useful in reducing oxidative stress and lipid profiles in beta major thalassemic patients.
Taavoni S (msc), Ekbatani N (msc), Kashaniyan M (md), Haghani H (msc),
Volume 14, Issue 1 (3-2012)
Abstract
Background and Objective: Sleep disurbance is considered to be one of the most common problems in menopausal women. Herbal supplements are being used as herbal supplemental medication to solve the problem. The aim of this study was to determine the effect of Sedamin capsule on sleep disorder among menopausal women. Materials and Methods: This randomized controlled trial study was done on 100 Menopausal women aged 50-60 with sleep disorder. Women randomly divided into intervention and contol groups. Subjects intervention group were received Sedamin capsule (530 mg Valerian root) twice a day for 30 days. Women in control group were received capsule (50 mg of carbohydrate) twice a day for 30 days. Demographic data form and Pittsburg sleep quality index was instrumented for the evaluation of disorder. Data analyzed with using independent T and ANOVA tests. Results: Mean score of sleep disorder peior and after intervention was 9.8±3.6 and 6.02±2.6 (P<0.05) in interventional group and 11.14±4 and 9.4±3.9 in controls, respectively. Also, 40% of the participants in the intervention group and 12% in the control group showed an improvement in the quality of sleep (P<0.05). Conclusion: This study showed that consumption of Sedamin capsule improves the quality of sleep in menopausal women with sleep disorder.
Bostani Fargoosh P, Dehbashi S, Aliarab A, Royani S, Hesari Z, Joshaghani Hr,
Volume 16, Issue 2 (7-2014)
Abstract
Background and Objective: Gestational diabetes is affected 3-12% of women and occurs at the final stage of second trimester. This study was done to determine the fructosamine and glycated hemoglobin level in pregnant women with abnormal glucose challenge test. Methods: This case – control study was carried out on 96 pregnant women with glucose challenge test (GCT)>140 mg/dl as cases and 96 pregnant women with GCT<140 mg/dl as controls. The serum fructosamine and glycated hemoglobin determined using ELISA and chemical methods, respectively. Results: In pregnant woman with abnormal GCT, there was a significant correlation with glycated hemoglobin and fructosamine. The glycated hemoglobin correlation was more significant compared to fructosamine (0.63 to 0.24). There was not significant correlation between GCT with fructosamine and glycated hemoglobin in individuals with normal GCT. Conclusion: The measurement of glycated hemoglobin is more accurate than fructosamine in pregnant women with abnormal glucose challenge test.
Taavoni S, Nazem Ekbatani N , Gooshegir A, Haghani H,
Volume 17, Issue 4 (12-2015)
Abstract
Background and Objective: Somatic and psychological altrations during menopause have negative impact on quality of life. This study was done to evaluate the effect of Aphrodit on somatic symptoms in postmenopausal women. Methods: In this clinical trial study 63 menopausal women were randomly divided into intervention and control groups. Subjects in interventional group were received Aphrodit capsule (40 mg of Tribulus terrestris fruits, 12.27 mg ginger, 33 mg saffron and 11 mg of cinnamon) for four weeks. Somatic symptoms of menopause (including hot flashes, night sweats and tachycardia) and sleep disorder and muscluskeletal disorder were evaluated using Menopause Rating Scale. Results: After intervention, the mean of hot flash score in interventional and control groups was 1.29±0.1 and 3.1±0.6 (P<0.05).The mean of sleep disorder score in interventional group and controls was 1.82±0.2 and 2.82±3.1 (P<0.05). The mean of muscluskeletal disorder score in interventional group and controls was 1.03±0.1 and 2.81±1.2 (P<0.05).There was no diference in the heart problem score between interventional and control groups. Conclusion: Consumption of Aphrodit capsule reduces hot flash, sleep disorder and muscluskeletal disorder in postmenopausal women.
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