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Breast cancer is the most common cancer in women. Histologic grading is one of the prognostic factors in breast cancer. The present study performed in analytic descriptive method and based on the slide review of beast biopsies received in the pathology department of 5th Azar Hospital from 1976 to 1978, and on the basis of Bloom-Richardson criteria (Mitoses, tubule formation and nuclear pleomorphism). The results are consist of: 1) Infiltrating duct carcinoma is the most common histopathologic form, and tubular carcinoma is the least common 2) The most common age is 36-45 years 3) There is meaningful relationship between mitoses and tubule formation and between pleomorphism and tubule formation. But there is no relation between nuclear pleomorphism and tubule formation in the tumor. Histologic grading of breast carcinoma should be reported by pathologist for clear determination of prognosis and also the best choice for management of the tumors.

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Pseudoxantoma Elasticum is a hereditary disease with prevalency of 1 among 160000 people in which yellowish papules and plaques are symmetrically distributed in abnormally lax skin of the neck, axilla, groin, and cubital and popliteal spaces, other parts of the body are less frequently involved. Patient that has been presented is 30 years old Turkman woman referred to 5th Azar Hospital with skin problems contains skin folds at neck, yellowish papules at ant, abdomen, cubital area and neck. After skin biopsy, histopathological findings confirmed clinical diagnosis of Pseudoxantoma Elasticum.