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Showing 27 results for Amani
D.qujeq (ph.d), S.vasegh (dmd), A.zamanian (dmd), Volume 3, Issue 1 (Spring & Summer 2001)
Abstract
Sialoprotein is one of the most abundant non-collageneous and phosphorylated glycoproteins in human. This protein plays an important role in the structure of human teeth. The aim of this project is to measure the amount of dentin Sialoprotein in the healthy and decay teeth to evaluate the variation in the teeth structure. In this investigation 50 decay teeth has been collected from patients referred to the clinic. The dentin was separated and placed in liquid Nitrogen. One gram of each dentin was washed with distilled water for 30 mins and subsequently the dentin was powdered, and relocated to the gaunidin-Hcl tris buffer, and incubated at 4°C for 48 hrs. The dentin powder was centrifuged at 3000 g for 20 mine. The supernatant was discarded, and the samples again was centrifuged at 10000 g. Finally one ml of this supernatant transferred to the sepharose column and washed with gaunidin-Hcl tris at 1 ml/min. The fractions obtained by chromatography was monitored by electrophoresis. The amount of decay teeth Sialoprotein was 17.23±1.45 ng/l and in the healthy teeth was 26.39±4.27 ng/l. The results from this study indicate that the Sialoprotein content in patient dentin decreased by about 1.5 time compared normal subjects.
M.zamani (md), M.arab (md), Sh.nasrollahi (md), Kh.manikashani (md), Volume 7, Issue 1 (Spring & Summer 2005)
Abstract
Background&Objective: Primary dysmenorrhea is one of the common causes of absence from work place and life quality among women. According to some studies, fish oil administration results in production of weaker prostaglandin’s (PG) and reduces the severity of dysmenorrhea. The aim of this study is to experience the efficacy of fish oil on dysmenorrhea, which is a cheap drug and with low side effects. Materials&Methods: In this clinical trial, the students separated into two groups those affected with primary dysmenorrhea by referring to girls' high schools and complete the questionnaires. In the next stage randomly were selected two groups each group included 22 students with primary dysmenorrhea. In first group fish oil capsules and the other group placebo were recommended for duration of two months. These students were evaluated before drug recommendation, at the end of two months treatment and two months afterward. In these three stages pain severity by VAS (Visual Analogue Scale) system and pain duration by Cox scaling system were be recorded in each group. Results: There is not meaningfull statistically difference in the average age, age of menarche, menstrual condition (regular or irregular) and accompaniment with symptoms of PMS (premenstrual syndrome) between fish oil and placebo groups. Before recommendation of capsules the average of pain severity did not have a meaningful statistically difference between two groups. The average pain duration also had similar situation. After two months treatment, the average of pain severity (VAS) in fish oil group was significantly less than which in placebo group (p<0.05). Also the average of pain duration in fish oil group was less than which in placebo group with a statistical difference of (p<0.05). Moreover, two months after the end of treatment the average of pain severity (VAS) and pain duration (hour) had meaningfull statistically difference between fish oil and placebo groups and were less in fish oil group. Conclusion: As compared with placebo, the fish oil capsule after two months of consumption had a significant effect on reduction of pain severity and duration in primary dismenorrhea. Also two months afterward from the end of this clinical trial the effect was more than placebo.
Sh.nasrolahi (md), Sh.alimohammady (md), M.zamani (md), Volume 8, Issue 1 (3-2006)
Abstract
Background&Objective: Precelampsia with prevalancy of 5-10% is one of the important causes of maternal morbidity and mortality and neonatal prematurity that prevention of it has aessential role in reduction of maternal and fetal mortality. Pathogenesis of disease is endothelial dysfunction and free radicals can exaggerated of endothelial damage.this study designed to evaluate antioxidants (vit E,C) effect on preeclampsia in primipar women. Materials&Methods: This study was a randomized clinical trial in 580 primipar women that randomized in two treatment and control groups. To the Treatmet group in 18-22w of gestation during routin prenatal care vitamin E (400 IU) and vitamin C (lg) administrated daily untile end of pregnany. Control group recieved routin ferrous sulfate and incidence of preeclampisa compaired in two-group .Data analyzed by chi-square test. Results: Incidence of preeclampsia was 1.7% in treatment group and 6.2% in control group (p<0.05). Conclusion: antioxidant (vit E,C) have an effect on reduction of preeclampsia incidence.
V.khori (phd), M.naebpour (phd), E.rakhshan, A.mirabbasi, M.zamani (msc), Volume 8, Issue 2 (7-2006)
Abstract
Background & Objective: Pharmacological studies and traditional medical literature point to the cardiovascular effects of the Citrus aurantium L. (Rutaceae) in many instances. In the present study, we used isolated perfused AV-node of rabbit as an experimental model to determine the effect of various concentrations of essence of Citrus aurantium (0.1-0.3 v/v) on electrophysiological properties of isolated heart. The second goal of the present study was to assess the protective role of essence of Citrus aurantium on arrhythmogenic effects of ouabain. Materials & Methods: This was a semi-experimental study. We used isolated perfused rabbit AV-nodal preparation, in three groups. In the first group, the effect of various concentration of the Citrus aurantium (0.1, 0.2, 0.3 ml/l) was assesed on the AV-node. In the second and third groups, the effect of Citrus aurantium was tested in the presence of ouabain (0.1?molar) and verapamil (0.1?molar). We used 6 rabbit in each group. Statistical analysis was preformed by SPSS Mean±SE was used in the all results. Results: Our results showed depressant effects of extract of Citrus aurantium on Wenchebach Cycle Length (WBCL), AV Conduction Time (AVCT), Effective and Functional Refractory Periods (ERP & FRP). Rate-dependent properties such as Facilitation and fatigue significantly increased by Citrus.a (0.3ml/l). We had significant increase in the AVCT (32.6±3.6 to 40±6.08 msec) and FRP (147±5.1 to 166.6±3.6 msec) by Citrus.a. We had a protective role of Citrus aurantium on ouabain induced AV-nodal depression. The magnitude of facilitation and fatigue in the concentration of 0.3 C.aurantium was 7.5±0.3 and 6.5±0.5, respectively. Conclusion: The above results indicated potential inhibitory and antiarrhythmic effect of Citrus aurantium in treating supraventricular tachyarrhythmia.
Kabirzadeh A, Zamani Kiyasari A, Bagherian Farahabadi E, Mohseni Saravi B, Kabirzadeh A, Tavasoli Ashrafi A, Volume 9, Issue 1 (3-2007)
Abstract
Background & Objective: Burning is a general health problem and is also a global injury as well as a very serious sanitary issue in industrial and developing countries. In its severe form, burning can claim lives. It seems essential in every society to analyze burning, to study the causes of burning, treatment outcomes and the death rates, etc. to find proper preventive measures. Materials & Methods: In this cross-sectional study, the medical records of all patients who were hospitalized and finally deceased during the years 2002 and 2004 in Zare' teaching hospital, Sari, were examined. Some variables including the age span average, the degree and percentage of burning, patients' residence, gender, the cause of burning (i.e. boiling water, fire, acids and explosives), average hospitalization period, surgery and also the abundance of self – burning attempts were examined. Results: This study indicate that during these 3 years the total number of those who died from burns was 506 (23.4%). The residential places were in Mazanderan province (41.7%), Golestan province (41.4%), and Gilan province (10.2%). The abundance of burning ranges as below: The 2 and 3 degree of burning at 91.8%. Regarding the percentage of burns, 31.7% of abundance pertains to burning at 90% and more. The greatest external causes leading to burns are petrol, gas, and gas oil at 57.9%. Also, the percentage of burns does not have much influence on death rate among 50 – year – olds and older people. Conclusion: This study indicated that the importance of death between burned patient in special sex and age. To establish hospitals, some issues must be considered as: distance, transportation, route dangers, characteristics of area, existing epidemiological survey, and finally the epidemics and event statistics.
Nasrolahi Sh, Zamani M, Volume 9, Issue 2 (7-2007)
Abstract
Background&Objective: Ectopic pregnancy is a main cause of maternal death and is 10-15% of refered patint to first trimester emergency ward. Due to importance of early detection and prevention of excessive blood loss in Ectopic pregnancy this study designed that evaluated the correlation between vital signs and quantity of hemo-peritoneum and except of traditional vital sign another method with more sensivity can be used in detection of tubal rupture and nessersirily of Emergency surgary. Materials&Methods: This study is a analytic cross sectional design in 105 patients had diagnosis of ruptured ectopic pregnancy in fatemieh hospital. positive predictive value and sensitivity and specifity of pulse rate, BP and shock Index (SI) in correlation to ruptured Ectopic pregnancy and hemoperitoneum evaluated. Results: Hundred five patients were studied (70 ruptured EP and 35 unruptured EP). Mean of shock index in unruptured and ruptured EP was 0.6±0.29 and 0.94±0.22 respectively that was nonsignificant. (p<0.05) Sensitivity of pulse rate, systolic pressure and shock Index (Pulse/SBP) was 17.6%±9%, 32.4 %±10% and 91.4%±6% respeictively. negative predictive value was 34.1%, 38.7 % and 50% respeictively.mean primary Hb had no difference in two group. Conclusion: Normal vital sign alone are poor predictors of ruptured ectopic pregnancy and shock Index (Pulse/SBP) Correlate best with the quantity of intaperitoneal hemorrhage.
Leili Chamani-Tabriz (md, Mph), Hojjat Zeraati (phd), Soheila Asgari (student of Msc), Soroor Asadi (md), Saeed Zarei (md), Volume 10, Issue 4 (12-2008)
Abstract
Background and Objective: Genital herpes is increasing in Asia and the world. Based on other studies, knowledge has an important role in reducing high risk sexual behavior. In this study we evaluated knowledge among Shahid Beheshti University students as a sample of young and educated population of Iran. Materials and Methods: This cross-sectional study carried out on 409 of Shahid Beheshti University students in Tehran - Iran at Autumn 2004. Research material was questionnaire and data analyzed by SPSS-13, T-student, Chi-square, Mann-Whitney, Kruskal-Wallis Tests. Results: Mean±SD of level of knowledge, nature and transmission of genital herpes was 26.5±26%, 23.7±24.2% and 30.56±36.8%, respectively. The level of knowledge about signs, treatment and prevention of disease was 18.8%, 16.4% and 46.2%, respectively. There was a significant relation between age, marital status and education with knowledge (P<0.05). The level of knowledge among engineering students was higher than humman sciences students (P<0.05). Conclusion: Based on our study, most of participants had no enough knowledge about genital herpes. Most of participants were willing to know more about it as they obviously welcomed to our pamphlets. It seems that educations about genital herpes should be added to educational programs.
Amani F (phd), Kazemnejad A (phd), Habibi R (phd), Hajizadeh E (phd), Volume 12, Issue 4 (12-2010)
Abstract
Background and Objective: Mortality rate and causes of death is one of the main components in health planning at each society. This study was done to show the pattern of mortality trends in Iran during 1970-2009. Materials and Methods: In this cross-sectional descriptive study related data to 9740656 deaths registered in National Organization Civil Registration were surveyed and analyzed during 1970-2009. SPSS software and statistical descriptive methods were applied to evaluate the data. Results: 60.4% of all registered death was in rural areas. 61.1% were male. Crude death rate according the current statistics decreased from 13 per 1000 in 1970-75 to 5 per 1000 in 2005-09. Life expectancy with 28.6% increased from 55.2 years in 1970-75 to 71 years in 2005-09. Conclusion: This study showed that all mortality indicators in Iran were lower than other part of the world. There was a general decreasing in infant mortality rate in last three decade. Also the death registry system has been improved during study years.
Arsang Sh (msc), Kazemnejad A (phd), Amani F (phd), Volume 13, Issue 3 (10-2011)
Abstract
Background and Objective: The characterization of any disease have important role for the evaluation and control strategy and programming of diseases. This study was done to determine the epidemiology of Tuberculosis in Iran during 2001-08. Materials and Methods: In this descriptive cross sectional study, Annual percentage change (APC), average annual percentage change (AAPC) of Tuberculosis incidence rate, mortality of Tuberculosis, case detection rate, success percentage in Tuberculosis treatment and relapses cases during 2001-08 have been studied in Iran. Linear segmented regression model was used for analysis trend of Tuberculosis and estimate parameters. Results: The trend of Tuberculosis smear positive (SP) incidence rate was reduced in Iran during 2001-08. Anually, 4.1% and 3.6% reduction took place in incidence rate and relapses cases, respectively. Tuberculosis mortality decreased annually by 6.8% and success in case detection increased by 2.5%. The Tuberculosis treatment though AAPC is decreasing by 0.5%. The trend of Tuberculosis are higher among women and in both sexes over 65 years of age. Conclusion: This study showed that trend of SP pulmonary tuberculosis and treatment success rate is decreased, but case detection was increased.
Amani F (phd), Mahdavi A (msc), Hamedi B (bsc), Zarerasouli S (bsc), Kargarjahed Z (bsc), Mohammadzadeh E (bsc), Volume 13, Issue 3 (10-2011)
Abstract
Background and Objective: Patients consent for medical care is a legal requirement. Consent is a document that patient must be necessary aware about all risks of surgery, treatment strategy, Substitution and the risks involved by physician. This study was done to evaluate status of filled consent form of hospitalized patients in Ardabil – Northwest of Iran. Materials and Methods: This descriptive cross sectional study was done by interview with patients and accompained patients in hospitals of Ardabil – Northwest of Iran during 2010. Patient demographics and other variables gathered by a questionnaire. Data was analyzed by Chi-Square test. Results: 86 (57%) of patients were female and 64 (43%) male. 35 (23%) were illiterate and 92 (61%) under diploma. 45% of patients get information about their illness from doctors. According to patient ideas, 13% of reception personals did not complete consent form. 65 (43.3%) of patients stated that the context of consent form was unreadable and long. Rate of completing form for patients were 87%. 40% of completed forms was not signed by witnesses. The patients and relatives were not satisfied with the form itself, and this observation statistically was significant (P<0.001). Conclusion: This study showed that validity of completed consent forms are low and it is necessary to design programs for improvement the quality of filling the consent forms.
Kaviannejhad R, Tayyebi Arasteh M , Kohan M, Moradi M, Alitalab J , Amani S, Volume 14, Issue 3 (10-2012)
Abstract
Background and Objective: Post pain operative is common and a major complication which lead to numerous dangerous effects in various organs. The purpose of this study was to determine the effect of methocarbamol on postoperative pain following cholecystectomy. Materials and Methods: In a randomized, double – blind clinical trail study 60 ASA I, II patient in two group (n=30 in each group) between 30-50 years old and weigh lower of 100kg undergone general anesthesia for cholecystectomy. Elective surgery was selected in Besat Hospital, Sanandaj, Iran during 2008. Both group did not receive premedication and under similar condition of general anesthesia. Interventional group received 500mg Methocarbamol intravenus slowly and the control group received 5ml placebo slowly after operation. The pain score were measured by visual anesthesia scale (VAS) on the 1, 3, 6, 12 and 24 hours after operation and if necessitated narcotics (PRN, VAS>4) were prescribed. Data were analyzed using SPSS-16, ANOVA, Chi-Square and student’s t-tests. Results: There were no significant differences between two groups in terms of age, gender. The mean of score pain was lower for interventional group at 6.24 hours after operation (P<0.05). But no significant differences was observed at 1, 3 and 12 hours. The prescribe narcotic in interventional group was lower compared to controls (P<0.05). Conclusion: According to analgesic effects and low prescribe narcotics, it is suggested to use methocarbamol after operative due to analgesic effect.
Banitalebi E (phd), Ghatre Samani K (phd), Mardani G (msc), Soheili A (pharm.d), Ansari Samani R (msc), Teimori H (phd), Volume 14, Issue 4 (12-2012)
Abstract
Background and Objective: Sphingosine-1-phosphate (S1P) is involved in regulation of proliferation, differentiation, hypertrophy and anti-apoptosis and activation of satellite cells. This study was done to evaluated the effect of 8 weeks resistance training on sphingosine-1-phosphate level and gene expression of SK1 enzyme, isoforms of MHCs in skeletal muscles of male Wistar rats. Materials and Methods: This experimental study was done on Twenty four 8-week-old 190-250 gr male Wistar rats. The rats were allocated randomly into control (N=12) and training (N=12) groups. Resistance training was done using a 1 meter height ladder with 2 cm grid with an 85 degree incline, and weights attached to rat's tails. The content of S1P present in the chloroform layer was determined by means of high performance liquid chromatography (HPLC). Determination of relative mRNA expression was performed by Real-time PCR. Data were analyzed using SPSS-17, Kolmogorov-Smirnov and independent t-test. Results: Resistance exercise training increased the total content of S1P in FHL (fast-twitch) and soleus (slow-twitch) muscles in comparison with control group (P<0.05). Resistance exercise training changed the gene expression of FHL SK1, SOL SK1, FHL MHC I, Sol MHC I, FHL MHC IIa, Sol MHC IIa, FHL MHC IIb, Sol MHC IIb, FHL MHC IIx, Sol MHC IIx in comparison with control group (P<0.05). Conclusion: This study showed that S1P level and gene expression of SK1, MHCs increased at skeletal muscles after training.
Zamani M (msc), Rasooli H (phd), Mehdizadeh M (phd), Nobakht M (phd), Zamani F (bsc), Soleimani M (phd), Volume 14, Issue 4 (12-2012)
Abstract
Background and Objective: Brain ischemia is one of the most important factor of morbidity and mortality and leaving many people with mental and physical disabilities. Until now there are no appropriate medications to prevent and cure ischemic injury. This study was done to evaluate the protective effect of Adenosine A1 receptor and ascorbic acid on hippocampal neuronal density and memory disorder in ischemia reperfusion induced Rats. Materials and Methods: This experimental study was performed on the hippocampus pyramidal neurons on 56 male BALB/c mice. Animals randmly allocated into 8 groups (N=7) including: 1) intact, 2) ischemic control group, 3) ischemic, plus agonist and adenosine of A1 receptor, 4) ascorbic acid (100 mg/daily), 5) ischemic plus agonist adenosine receptor (1 mg/1 kg) one week after ischemia, 6) ischemia, ascorbic acid befor and after ischemia and A1 receptor (1 mg/1 kg) agonist after ischemia, 7) A1 receptor, antagonist (2.25 / 1 kg), one weed after ischemia, 8) Ascorbic acid (100 mg/1kg) before and after ischemia plus A1 receptor antagonist (2.25 / 1 kg) after ischemia. Ischemia induced by clamping of common carotid artery and the drugs was injected subsequently into peritoneum after reduction of inflammation of ischemic zone. The Y-maze memory test performed after completing the treatment period, afterward brains fixed and prepared for microscopic nissl staining method. The counting of pyramidal cells were performed at 53500 square micrometer of CA1. Data were analyzed using SPSS-15 and ANOVA test. Results: The Y-maze test showed extensive deficit in short-term memory in ischemic group (PA=200) but in treatment groups this deficit significantly reduced (PA=243, 248 and 265). The normal neuronal cell in ischemic group was significantly lowered (n=87) than treatment groups (n=111, 105 and 125) including ascorbic acid group (125), adenosine receptor agonist (105) and ascorbic acid plus agonist adenosine receptor (111). The number of normal neuronal cell in ischemic groups significantly is reduced compared to treatment group (P<0.05). Conclusion: This study showed that concurrent treatment of ascorbic acid and Adenosine A1 receptor agonist can significantly reduce the complications caused by brain ischemia in CA1 area of hippocampus.
Houshiyar A (md), Fouladi N (phd), Amani F (phd), Alimohammadi Asl H (phd), Ghorbani F (md), Volume 14, Issue 4 (12-2012)
Abstract
Background and Objective: Irritable bowel syndrome (IBS) is the most prevalent gastrointestinal disorder and is one the common conditions seen by gastroenterologists in their daily practice. This study was done to determine the prevalence of celiac disease in patients with irritable bowel syndrome in Ardabil-Iran. Materials and Methods: This descriptive study was conducted on 105 patients with IBS whome referred to the gastroenterology unit in Ardabil-Iran during 2009-10. Serum IgA anti tTG were measured all patients with positive for antibodies against tTG were candidated for upper endoscopy and biopsy. Data were analyzed using SPSS-16, t-test, Chi-Square and Fisher’s exact tests. Results: The average age of IBS subjects were 31.4±10.14 years (range 16-63 years). Celiac disease was diagnosed in 14 subjects (13.5%). The celiac patient age were 22-55 years with mean of 34.93±9.47. Among celiac afflicted patients IBS type D and M observed among 10 and 4 patients, respectivley. Celiac affected female constituted 12 (85.7%) of all patients (P<0.05). 10 of these patients were IBS-D and 4 with IBS-M. From 14 celiac patient 4 (28.57%) were family related, but this rate among IBS patient was 3.3%, this difference was significant (P<0.05). Conclusion: This study showed that the prevalence of celiac in patients with IBS is found to be 13.5% which seem is more than ther studies in other parts of Iran.
Zand H, Amani M, Mohammadi V, Valinezhad F, Hosseinzadeh S, Volume 15, Issue 1 (3-2013)
Abstract
Background and Objective: The exposures related to the department of radiology can be considered as harmful agent for human. This study was done to assess the partial distribution of the equivalent dose in radiology waiting room in Ardabil, Iran. Materials and Methods: This descriptive analytical study was done in the radiology department and related waiting rooms of 4 teaching hospital and 3 private radiology sonography centers in Ardabil, Northwest of Iran, during 2011. The variables including type of radiography, the number and condition, staying duration in waiting room were considered for dosimetry. Data were analyzed using SPSS-18 and Chi-Square test. Results: The lowest radiation dose belong to one specialist radiology sonography center with 0.2±0.002 µS.h-1V, but for each radiography were determined to be 0.00275±0.004 µS.h-1V. The highest radiation dose belong to one specialist radiography sonography center with 0.4±0.045 µS.h-1V and for each radiography was 0.016±0.0006 µS.h-1V. Two teaching hospitals accompanied with three privates centers showed to have radiation dose-rate higher than 0.3 µS.h-1V (P<0.05). Conclusion: This study showed that the increasing radiation-dose rate (higher than 0.3 µS.h-1V) in teaching hospitals and private centers can be related to either the unit life or inadepuate of radiological protective shield.
Daryanoosh F, Shkibaie M, Zamanie A, Mohammadi M, Volume 17, Issue 3 (10-2015)
Abstract
Background and Objective: Alpha lipoic acid (ALA) is a powerful biological antioxidant which is involved in metabolism and energy production as a co-factor in mitochondrial dehydrogenase enzyme complex. This study was done to evaluate the effect of aerobic exercise and alpha lipoic acid supplement on insulin resistance in females with type 2 diabetes. Methods: In this quasi-experimental study, 44 females with type 2 diabetes divided into four groups including: control, supplementation, training and supplementation + training groups. Patients of supplementation and complex (supplementation + training) groups took three 100mg ALA capsules per day for eight weeks. The training program consisted of 8 weeks and three sessions per week. In each session, the subjects warmed up for 10-15 minutes, ran on a treadmill with the intensity of 40-50% of maximum heart rate for 30 minutes and then cooled down for 5-10 minutes. Blood samples were taken after 12-14 hours fasting in two stages - the beginning and the end of the eighth week. Results: Eight weeks of taking ALA supplements significantly reduced patients' insulin resistance (P<0.05). Eight weeks of running on a treadmill with an intensity of 40-50% of maximum heart rate non-significantly reduced insulin resistance in the training group compared to the controls. In the supplementation + training group a significant reduction of insulin resistance was observed (P<0.05). Conclusion: Alpha lipoic acid supplementation reduces insulin and insulin resistance. While, reduction in fasting blood glucose level causes reduction in insulin resistance in the combination of supplementation and training.
Esfandiari P, Amani J , Imani Fooladi Aa, Forghanifard Mm , Mirhossaini Sa, Volume 17, Issue 3 (10-2015)
Abstract
Background and Objective: Enterotoxigenic Escherichia coli (ETEC) are the most common agent which causes diarrhea, worldwide. ETEC is colonized along the cells and then producing heat-labile (LT) and heat-stable enterotoxigenic which enter into intestinal epithelial cells and causes water and electrolyte loss from intestinal epithelial cells and eventually cause diarrhea.This study was done to detect the heat-labile toxin in Enterotoxigenic Escherichia coli using PCR-ELISA technique. Methods: In this descriptive study, DIG-labeled PCR products were bounded to streptoavidin-coated wells of a microtiter plate and detected by anti-DIG–peroxidase conjugate. The biotin-labeled internal probe was used for verification of PCR products. Results: Heat-labile toxin was detected by PCR-ELISA method. The sensitivity of heat-labile toxin was 1.9 ng. This method did not cross-react with bacteria from this variety. Conclusion: PCR-ELISA method is 100 times more sensitive than conventional PCR method and due to lack of agarose gel and electrophoresis device it can be a good alternative to traditional method.
Soltan Dallal Mm , Keshtvarz M, Zamani S, Shirazi L, Volume 18, Issue 1 (3-2016)
Abstract
Background and Objective: Probiotics are beneficial organisms therapeutic within microbial flora. Shigella, Escherichia coli and Salmonella are the most common cause of intestinal infectious diseases that lead to morbidity and mortality in infant and children worldwide. The aim of this study was to evaluate anti-microbial activity of Lactobacillus acidophillus and Lactobacillus ruteri against entero-pathoges by in vitro and in vivo methods. Methods: In this experimental study, the therapeutic effect of the lactobacillus acidophilus ATCC 4356 and ruteri ATCC 23272 against Shigella sonnei ATCC 9290, Escherichia coli ATCC 25922 and Salmonella enterica BAA-708 were evaluated by in vitro (spot agar) and in vivo (BALB/c mice) methods. Weight improvment and survival rate in mice were recorded. Results: Lactobacillus acidophillus and ruteri had protective and therapeutic effect against diarrhea caused by pathogenic bacteria. Probiotics reduced the weight, colonization of pathogens and increased the survival rate of animals (P<0.05). Conclusion: Lactobacillus acidophillus and ruteri has anti-microbial activity and their consumption can be effective in the prevention and also the treatment of intestinal disease.
H Fathi , N Mohammad Shahi , A Latifi , A Zamani , F Shaki , Volume 18, Issue 3 (10-2016)
Abstract
Background and Objective: The flowers of Citrus aurantium L. are traditionally used in the treatment of neurological disorders such as seizures, epilepsy and neurasthenia. With regard to the importance of nausea and vomiting and effects of strengthening the stomach of Citrus aurantium L. extract, this study, was done to determine the antiemetic effect of the metabolic, aesthetic and aqueous extract of flowers of Citrus aurantium L. in young chickens.
Methods: In this experimental study, induction of emesis was performed in 138 young chickens
(23 groups, n=6) using copper sulfate (60 mg/kg, orally) and ipecac (600 mg/kg, orally). The aqueous, methanolic and acetonic extract at doses of 50, 100 and 250 mg/kg/bw were injected intraperitoneally (i.p.) and metoclopramide (as positive control). The number of nausea was recorded 50 and 20 minutes after copper sulfate and ipecac administration, respectively.
Results: Our results showed that all kind of extract at doses of 100 and 250 mg/kg significantly inhibited copper sulfate and ipecac induced–emesis that showed better effect than metoclopramide. Also, comparison of antiemetic effect of different extract revealed that methanolic, aqueous and acetonic had better effect on prevention of nausea, respectively in comparision with metoclopramide.
Conclusion: All kinds of Citrus aurantium (Methanolic, Aesthetic and Aqueous) showed antiemetic effect due to copper sulfate and ipecac dose dependly in Young chickenin in comparision with metoclopramide.
A Moezy , Sh Gharamaninia , A Gharamaninia , M Rezaei Hemami , Volume 19, Issue 2 (7-2017)
Abstract
Background and Objective: One of the most common musculoskeletal injuries in modern societies is neck and shoulder pains which often lead to postural disorders and soft tissue shortenings. This study was done to compare the length of shoulder girdle’s muscles in healthy subjects and patients with shoulder and neck pain.
Methods: This case-control study was done on16 patients with chronic neck- shoulder pain as cases and 15 healthy subjects as control group. Length of upper trapezius, pectoralis major and minor muscles was evaluated with functional tests. Also, the range of shoulder abduction and external rotation and cervical flexion and lateral flexion were measured by goniometer.
Results: Significant differences between patient and control groups were found in pectoralis major and minor muscles length in involved side (P<0.05) and also in neck active range of lateral flexion (P<0.05). Furthermore, there were significant differences between shoulder active range of abduction and external rotation (P<0.05) in the groups.
Conclusion: This study confirmed a significant reduction in range of motion in the neck and shoulder and also a remarkably shortening in the muscles of in the involved side.
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