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Background and Objective: The prevalence of behavioral disorders in children with mentally ill parents are higher compared with children of healthy parents. This study was carried out to assess the behavioral disorders in children with major depressive mothers. Materials and Methods: This case – control study was done on 50 children (6-11 years) of mothers with major depressive as case group and 50 children of healthy mothers as controls in Bandar Abbas, Iran drung 2009. With psycological interview, DSM-4-R and Beck tests, deprsion in mother were confirmed. The psycological health of control mothers were confirmed using Minnesota multiphasic personality inventory (MMPI) and questionnaire health general (QHG). The behavior disorders of children in two groups were compared using Achenbach child behavior questionnaire. Data were analyzed using SPSS-17, Chi-Square and student’s t tests. Results: Somatic complains, anxiety and depression, social problems, thought problems, externalization, internalization and antisocial behavior scores, were significantly higher in cases compared to controls (P<0.05). No significant differences in isolation and attention behavior were noticed between cases and controls. Conclusion: Behavior disorders in children with depressive mothers are common.

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Background and Objective: Disclosure of cancer is one the main challenges in caring of patients with cancer, since it may have adverse effects on the patients quality of life. This study was done to determine life quality of cancer patient with or without self awareness. Materials and Methods: This case – control study was conducted on 300 cancer patients in Shahid Ghazi-Tabatabaei hospital in Tabriz, Iran during 2009. The cancer patients included 150 subjects aware of their cancer diagnosis as cases and 150 unaware patients as controls. The patient's quality of life was assessed Using EORTC QLQ-C30 questionnaire. Data were analyzed using SPSS-17 and student’s t-test. Results: The mean±SD of quality of life among aware and unaware patients were 64.18±18.85 and 65.16±19.02, respectively. There was no significant difference of quality of life between two groups. Life social dimension in unaware patients significantly was more than aware patients (P<0.05). Conclusion: Patients awareness of cancer have no effect on their quality of life.

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Background and Objective: Autism spectrum disorder is a genetic-based cognitive and neurobehavioral disorder characterized by impairment in social interaction, verbal and non-verbal communication and repetitive motor behavior. This study was done to evaluate the verbal fluency and working memory deficit in first-degree relatives of autistic children. Materials and Methods: In this case - control study, 49 first-degree relatives of autistic children from 33 families (32 mothers, 10 fathers, 6 sisters, and 1 brother) supported by Isfahan autism association were selected and compared with 51 first-degree relatives of typical children (23 mothers, 16 fathers, 7 sisters, and 5 brothers) of 27 families during 2010. The assessing tasks were phonemic and semantic verbal fluency tests to assess verbal fluency and forward and backward digiti span tests to assess low load and high load working memory. Data were analyzed using SPSS-19 and independent t-test and paired t-test. Results: Autistic relatives showed significant poor performance in phonemic (11.46±3.3 V.S. 14.08±3.8), semantic verbal fluency (16.83±3.3 V.S. 19.23±3.9), forward digiti span (5.22±0.6 V.S. 5.55±0.9) and backward digiti span (3.65±0.98 V.S. 4.14±0.8) (P<0.05) compared to healthy children of first-degree relatives. Conclusion: This study showed that parents and siblings of autistic children have a lower performance in phonemic and semantic, low and high load verbal fluency, which might be transmitted genetically.

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Background and Objective: The utrine cervical cancer is the third common cancer among women word-wide. Oral contraceptives (OCs) have characterized as one of the possible risk factors for cervical cancer which are daily used by millions of women. The objective of this study was to determine the relationship between utrine cervical carcinoma and oral contraceptives. Materials and Methods: This case - control study was done on 128 patients with utrine cervical cancer as cases and 128 healthy women as controls in Tehran, Iran during 2008. The cases matched with controls according to age, history of abortion, number of deliveries, and social-economical status. Data were analyzed using SPSS-11, student’s t-test, Chi-Square, Pearson's correlation and Fisher’s exat tests. Results: Significant correlation was observed between utrine cervical cancer and the history of using and duration of oral contraceptives (P<0.05). Eighty-one (66.3%) and 46 (35.9%) of subjects in case and control groups used oral contraceptives, respectively. The possibility of utrine cervical cancer through oral contraceptives consumption was 3.072 (CI 95% 1.05-2.91) and this rate increased to 5.2 times after consuming the oral contraceptives for longer than 8 years. Conclusion: This study showed that the usage of oral contraceptives increase the possibility of utrine cervical cancer by 3 times.