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Depression and Its Association with Adherence to Gluten-Free Diet in Patients with Celiac Disease
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Ali Jafari1    , Zahra Norouzi 2, Fazel Isapanah Amlashi3 , Iman Shahabi Nasab3 , Puria Qadirian1 , Shahin Shah Yousefi4 , Mohammad Taqi Badeleh Shamushaki5 , Seyyedeh Fatemeh Mousavi Emadi6 , Sima Besharat7 |
1- Student Research Committee, Department of Nutrition, School of Health, Golestan University of Medical Sciences, Gorgan, Iran. Nutrition Sciences Student, Golestan Research Center of Gastroenterology & Hepatology (GRCGH), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
2- Medical Student, Golestan Research Center of Gastroenterology & Hepatology (GRCGH), Sayad Shirazi Hospital, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran. , z.norouzi77@yahoo.com
3- Medical Student, Golestan Research Center of Gastroenterology & Hepatology (GRCGH), Sayad Shirazi Hospital, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran.
4- General Practitioner, Golestan Research Center of Gastroenterology & Hepatology (GRCGH), Sayad Shirazi Hospital, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
5- Assistant Professor of Health Psychology, Golestan Research Center of Psychiatric, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
6- Assistant Professor of Gastroenterology and Hepatology, Zahedan University of Medical Sciences, Zahedan, Iran.
7- Associate Professor, Ph.D in Biomedicine, Golestan Research Center of Gastroenterology & Hepatology (GRCGH), Golestan University of Medical Sciences, Gorgan, Iran; Clinical Research Development Unit (CRDU), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran. |
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Abstract: (1102 Views) |
Background and Objective: Celiac disease is a malabsorption disorder that could result in various psychological consequences if patients do not adhere to a gluten-free diet. This study aimed to determine the frequency of major depressive disorder and its relationship with adherence to a gluten-free diet among patients with celiac disease.
Methods: This descriptive-analytical study was conducted on 47 patients with celiac disease (30 women and 17 men) with an average age of 40.88 ± 10.7 years who had been referred to the Golestan Research Center of Gastroenterology and Hepatology during the summer of 2019. Patients were invited to complete a 13-item Beck Inventory. Celiac Dietary Adherence Test (CDAT) was used to assess adherence from the patients' point of view, and Standardized Dietician Evaluation (SDE) was used to evaluate adherence to the diet from the interviewer's perspective.
Results: Overall, 28 people (59.6%) with celiac disease reported some degree of depression. Based on the SDE, the adherence rate of patients to a gluten-free diet was 83%. The association between adherence to a gluten-free diet and the prevalence of depression was not significant. There was also no significant association between the prevalence of depression and the gender and age of patients.
Conclusion: Based on the results, a high percentage of patients with celiac disease have symptoms of depression. However, there is no significant relationship between adherence to a gluten-free diet and the prevalence of depression.
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Keywords: Celiac Disease [MeSH], Depression [MeSH], Gluten-Free Diet [MeSH]
Article ID: Vol24-57 |
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Full-Text [PDF 446 kb]
(4192 Downloads)
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Type of Study: Original Articles |
Subject:
Psychiatry
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Jafari A, Norouzi Z, Isapanah Amlashi F, Shahabi Nasab I, Qadirian P, Shah Yousefi S, et al . Depression and Its Association with Adherence to Gluten-Free Diet in Patients with Celiac Disease. J Gorgan Univ Med Sci 2022; 24 (4) :98-103 URL: http://goums.ac.ir/journal/article-1-4120-en.html
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