:: Volume 23, Issue 2 (7-2021) ::
J Gorgan Univ Med Sci 2021, 23(2): 40-45 Back to browse issues page
Comparison of superior vena cava to aorta diameter ratio in three vessel view in fetuses with intrauterine growth restriction and normal growth fetuses
Ensieh Farhidzadeh1 , Laden Younesi Asl 2, Zeinab Safarpour Lima3 , Ghazaleh Amjad3 , Ida Roustaei3
1- Resident of Radiology, Shahid Akbarabadi Clinical Research Development Unit, Iran University of Medical Sciences, Tehran, Iran.
2- Assistant Professor, Department of Radiology, Shahid Akbarabadi Clinical Research Development Unit, Iran University of Medical Sciences, Tehran, Iran. , dr.ladanyounesiasl@gmail.com
3- Assistant Professor, Department of Radiology, Shahid Akbarabadi Clinical Research Development Unit, Iran University of Medical Sciences, Tehran, Iran.
Abstract:   (2959 Views)
Background and Objective: Intrauterine growth restriction (IUGR) is an obstetrical complication. IUGR increases the chance of neonatal death and obstetrical complications in comparison with normal pregnancy. Timely diagnosis of this condition allows effective interventions that decrease the morbidity and mortality. This study was done to compare of superior vena cava to aorta diameter ratio in three vessel view in fetuses with intrauterine growth restriction and normal growth fetuses.
Methods: This case control study was performed on 60 mothers in 25 to 37 weeks of pregnancy who were referred to radiology department of a hospital in Iran during 2018-19. 30 patients were diagnosed with IUGR and were included as case group. 30 healthy fetuses were included as control group. Routine ultrasonography was performed for evaluating placenta, fetuse, and amniotic fluid. Also, colour Doppler sonography was performed on umbilical vessels along with superior vena cava and ascending aorta for definite diagnosis of IUGR. Demographic data regarding fetuse’s age, pregnancy status, number of parities, and age of mother were also accumulated. The superior vena cava/aorta ratio (SVC/AO) was compared in IUGR and healthy fetuses. Based on their amniotic fluid, fetuses were divided into normal and mild oligohydramnios.
Results: There was a significant difference in SVC/AO diameter index between case and control groups (P<0.05). Mean SVC/AO ratio was significantly higher in IUGR fetuses in compared to healthy fetuses. There was no significant difference between normal and oligohydramnios fetuses either in case or control groups.
Conclusion: Implementation of SVC/AO diameter index in three vessels view sonography in screening programs for pregnant women can reduce neonatal morbidity and mortality.

Keywords: Fetal Growth Retardation [MeSH], Aorta [MeSH], Superior Vena Cava [MeSH]
Article ID: Vol23-24
Full-Text [PDF 1006 kb]   (9695 Downloads)    
Type of Study: Original Articles | Subject: Radiology
References
1. Bano S, Chaudhary V, Pande S, Mehta V, Sharma A. Color doppler evaluation of cerebral-umbilical pulsatility ratio and its usefulness in the diagnosis of intrauterine growth retardation and prediction of adverse perinatal outcome. Indian J Radiol Imaging. 2010 Feb; 20(1): 20-5. DOI: 10.4103/0971-3026.59747 [DOI] [PubMed]
2. Scifres CM, Stamilio D, Macones GA, Odibo AO. Predicting perinatal mortality in preterm intrauterine growth restriction. Am J Perinatol. 2009 Nov; 26(10): 723-28. DOI: 10.1055/s-0029-1223284 [DOI] [PubMed]
3. Frøen JF, Gardosi JO, Thurmann A, Francis A, Stray-Pedersen B. Restricted fetal growth in sudden intrauterine unexplained death. Acta Obstet Gynecol Scand. 2004 Sep; 83(9): 801-7. DOI: 10.1111/j.0001-6349.2004.00602.x [DOI] [PubMed]
4. du Plessis AJ. Cerebral blood flow and metabolism in the developing fetus. Clin Perinatol. 2009 Sep; 36(3): 531-48. DOI: 10.1016/j.clp.2009.07.002 [DOI] [PubMed]
5. Fleischer A, Schulman H, Farmakides G, Bracero L, Blattner P, Randolph G. Umbilical artery velocity waveforms and intrauterine growth retardation. Am J Obstet Gynecol. 1985 Feb; 151(4): 502-5. DOI: 10.1016/0002-9378(85)90278-9 [DOI] [PubMed]
6. Banu AA. Doppler velocimetry in the umbilical and middle cerebral arteries in fetuses with intrauterine growth retardation or fetal distress. Fukuoka Igaku Zasshi. 1998 May; 89(5): 133-44. [PubMed]
7. Seeds JW. Impaired fetal growth: definition and clinical diagnosis. Obstet Gynecol. 1984 Sep; 64(3): 303-10. [PubMed]
8. Seeds JW, Peng T. Impaired growth and risk of fetal death: is the tenth percentile the appropriate standard? Am J Obstet Gynecol. 1998 Apr; 178(4): 658-69. DOI: 10.1016/s0002-9378(98)70475-2 [DOI] [PubMed]
9. Gardosi J. Customized growth curves. Clin Obstet Gynecol. 1997 Dec; 40(4): 715-22. DOI: 10.1097/00003081-199712000-00005 [DOI] [PubMed]
10. Gardosi J, Francis A. Controlled trial of fundal height measurement plotted on customised antenatal growth charts. Br J Obstet Gynaecol. 1999 Apr; 106(4): 309-17. DOI: 10.1111/j.1471-0528.1999.tb08267.x [DOI] [PubMed]
11. Matsumoto-Runser J, Ando K, Yoda H. EP04.06: High SVC/Ao ratio in 3 vessel view can be one of the indicators for the placental insufficiency. Obstetrics & Gynecology. 2017; 50(51): 270. DOI: 10.1002/uog.18356 [Article] [DOI]
12. Albu AR, Anca AF, Horhoianu VV, Horhoianu IA. Predictive factors for intrauterine growth restriction. J Med Life. 2014 Jun; 7(2): 165-71. [PubMed]
13. Aditya I, Tat V, Sawana A, Mohamed A, Tuffner R, Mondal T. Use of Doppler velocimetry in diagnosis and prognosis of intrauterine growth restriction (IUGR): A Review. J Neonatal Perinatal Med. 2016 May; 9(2): 117-26. DOI: 10.3233/NPM-16915132 [DOI] [PubMed]
14. Karakus R, Seval Ozgu-Erdinc A, Esercan A, Dogan MM. Doppler Assessment of the Aortic Isthmus in Intrauterine Growth-Restricted Fetuses. Ultrasound Q. 2015 Sep; 31(3): 170-4. DOI: 10.1097/RUQ.0000000000000126 [DOI] [PubMed]
15. Kennelly MM, Farah N, Hogan J, Reilly A, Turner MJ, Stuart B. Longitudinal study of aortic isthmus Doppler in appropriately grown and small-for-gestational-age fetuses with normal and abnormal umbilical artery Doppler. Ultrasound Obstet Gynecol. 2012 Apr; 39(4): 414-20. DOI: 10.1002/uog.9076 [DOI] [PubMed]
16. Mari G, Picconi J. Doppler vascular changes in intrauterine growth restriction. Semin Perinatol. 2008 Jun; 32(3): 182-89. DOI: 10.1053/j.semperi.2008.02.011 [DOI] [PubMed]


XML   Persian Abstract   Print



Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 23, Issue 2 (7-2021) Back to browse issues page