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Effect of Interval Exercise on Serum Level of Fibroblast Growth Factor 21 and Myostatin in Obese and Overweight Males: A Clinical Trial Study
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Saeed Ramezani *    1, Ali Asghar Ravasi2 , Siroos Choobineh3 , Zeynab Firozeh4 |
1- Ph.D in Exercise Physiology, Bojnourd Education Department, Bojnourd, Iran. , rsaeid92@gmail.com
2- Professor of Exercise Physiology, Department of Physical Education, University of Tehran, Tehran, Iran.
3- Associate Professor of Exercise Physiology, Department of Physical Education, University of Tehran, Tehran, Iran.
4- Ph.D in Exercise Physiology, Bojnourd Education Department, Bojnourd, Iran. |
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Abstract: (5050 Views) |
Background and Objective: Differentiation of white adipose tissue into brown through hormonal and non-hormonal factors, causes weight loss and weakens in obese and overweight people. This study was performed to determine the effect of 12 weeks of interval exercise with different intensities on serum levels of fibroblast growth factor 21 and myostatin in obese and overweight males.
Methods: This clinical trial study was done on 47 obese and overweight males (20.5±0.73 years old). Subjects were randomly divided into four groups: control, interval exercise with low intensity, moderate intensity and high intensity. The exercise program consisted of 12weeks of interval exercise with light, medium and heavy intensity respectively with 58-63, 73-78 and 88-93 percent of Reserve heart rate for 25 to 63 minutes and three sessions per week. Serum indices of fibroblast growth factor 21 and myostatin were measured using fasting blood sample 48 hours before and after exercise program using ELISA method.
Results: Performing 12 weeks of interval training with different intensities was not contribute to significant changes in the serum levels of fibroblast growth factor 21 and myostatin. Implementation of interval exercise at moderate and high intensities was associated with reduction of body fat percentage and increasing in maximal oxygen consumption (VO2max) in overweight and obese men (P<0.05).
Conclusion: Performing 12 weeks of low, medium and high intensity interval training without changing the serum level of fibroblast growth factor 21 and myostatin has a beneficial effect on improving body composition and increasing VO2max in obese and overweight young males. |
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Keywords: Interval Exercise , Obesity [MeSH], Myostatin [MeSH], Fibroblast Growth Factor 21 [MeSH]
Article ID: Vol23-47 |
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Full-Text [PDF 719 kb]
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Type of Study: Original Articles |
Subject:
Exercise Physiology
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Ramezani S, Ravasi A A, Choobineh S, Firozeh Z. Effect of Interval Exercise on Serum Level of Fibroblast Growth Factor 21 and Myostatin in Obese and Overweight Males: A Clinical Trial Study. J Gorgan Univ Med Sci 2021; 23 (4) :1-9 URL: http://goums.ac.ir/journal/article-1-3900-en.html
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