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:: Volume 19, Issue 3 (10-2017) ::
J Gorgan Univ Med Sci 2017, 19(3): 47-51 Back to browse issues page
Prevalence of fatty liver in overweight, obese and normal children
M Tavakoli1 , M Sobhani Shahmirzadi 2, H Zaeri3 , A ZhianiAsgharzadeh4 , M Zare4 , MH Gharib5 , Gh Roshandel6
1- Resident in Pathology, Mashhad University of Medical Sciences, Mashhad, Iran
2- Assistant Professor, Pediatric Gastroenterologist, Children and Neonates Research Center, Golestan University of Medical Sciences, Gorgan, Iran , sobha48@yahoo.com
3- Assistant Professor, Pediatric Endocrinologist, Children and Neonates Research Center, Golestan University of Medical Sciences, Gorgan, Iran
4- Medical Student, Children and Neonates Research Center, Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran
5- Assistant Professor, Radiologist, Children and Neonates Research Center, Golestan University of Medical Sciences, Gorgan, Iran
6- Assistant Professor, Epidemiologist, Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
Abstract:   (13631 Views)
Background and Objective: Nonalcoholic fatty liver disease is the most common cause of liver disease worldwide and it is defined as a disorder of excess fat accumulation in the liver. This study was done to determine the prevalence of fatty liver among overweight, obese and normal children.
Methods: This historical cohort study was conducted on 90 children ages 5 to 13 years old in Taleghani pediatric theching hospital in Gorgan, north of Iran during 2014. Subjects according to Body Mass Index (BMI) classified into obese (95%>BMI), over weight (85-95% BMI) and normal (5-85% BMI). Childern were matched for age and sex. Liver enzymes (ALT Alanine aminotransferase and AST (Aspartate aminotransferase) and lipid profile includingTriglyceride: TG (High Density Lipoprotein: HDL and (Low Density Lipoprotein: LDL were measured and fatty liver evaluated based on sonographic parameters by a radiologist who didnot know children's BMI.
Results: The prevalence of fatty liver was 23.3% in obese children that was non- significantly higher than normal (16.7%) and over weight (16.7%) children. The prevalence of fatty liver was not significantly different between two sexes. AST was significantly higher in children with normal BMI in compared to obese and over weight children (P<0.05). The highest and lowest level of cholesterol was seen in obese and normal children (P<0.05).
Conclusion: This study showed that the prevalence of fatty liver non-significantly was higher in obese children in comparision with normal and over weight children.
Keywords: Fatty liver, BMI, Liver enzymes, Cholesterol, Child
Full-Text [PDF 226 kb] [English Abstract]   (13021 Downloads) |   |   Abstract (HTML)  (874 Views)  
Type of Study: Original Articles | Subject: Pediatric
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Tavakoli M, Sobhani Shahmirzadi M, Zaeri H, ZhianiAsgharzadeh A, Zare M, Gharib M et al . Prevalence of fatty liver in overweight, obese and normal children . J Gorgan Univ Med Sci 2017; 19 (3) :47-51
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Volume 19, Issue 3 (10-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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