[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Editorial Board::
Executive Members::
Instruction to Authors::
Peer Review::
Articles Archive::
Indexing Databases::
Contact Us::
Site Facilities::
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
:: Volume 19, Issue 2 (7-2017) ::
J Gorgan Univ Med Sci 2017, 19(2): 72-76 Back to browse issues page
Survival rate of patients with esophageal squamous cell carcinoma
A Basi1 , AR Nikofar2 , H Azhdarkosh3 , P Ordoni Aval * 4, Z Ordoni Aval5
1- Associate Professor, Hematologist and Oncologist, Iran University of Medical Sciences, Tehran, Iran
2- Assistant Professor, Radiotherapist, Iran University of Medical Sciences, Tehran, Iran
3- Assistant Professor, Gastroenterologist, Iran University of Medical Sciences, Tehran, Iran
4- Resident in Internal Medicine, Iran University of Medical Sciences, Tehran, Iran , parviz_ordoni@yahoo.com
5- Midwifer, Golestan University of Medical Sciences, Gorgan, Iran
Keywords: Esophagus, Squamous cell carcinoma, Survival, Chemotherapy, Chemoradiation, Surgery
Full-Text [PDF 221 kb] [English Abstract]   (15412 Downloads)     |   Abstract (HTML)  (11385 Views)
Type of Study: Original Articles | Subject: Oncology
Abstract:   (1318 Views)

Background and Objective: Squamous carcinoma accounts for the majority of esophageal carcinoma worldwide. This study was done to evaluate the survival rate of patients with esophageal cancer in Iran.

Methods: This historical cohort study was carried outon 105 patients with esophageal squamous cell carcinoma whom admitted to Firoozgar hospital in Tehran, Iran during 2009-14. Patients with esophageal squamous cell carcinoma were treated with chemoradiation either with or without surgery.

Results: The mean age of patients was 63 years. Frequency of esophageal cancer in both sexes in the age group 51-60 years was higher than other groups. 5-year survival in patients with esophageal cancer treated with chemoradiation without surgery was 9.5% and in patients treated with chemoradiation with surgery was 31.7% (P<0.05). One-year, three-year and five-year survival rate in patients were treated with chemoradiation with or without surgery was 68.5%, 38% and 22.8%, respectively.

Conclusion: The survival rate of patients with esophageal cancer is very low, but the treatment with chemoradiation with surgery can increase life expectancy of patients.

References
1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013 Jan; 63(1): 11-30. doi:10.3322/caac.21166
2. Malekzadeh R, Semnani Sh, Sadjadi A. [Esophageal Cancer in Iran]. Govaresh. 2008; 13(1): 25-34. [Article in Persian]
3. Semnani Sh, Besharat S, Arabali A, Kestkar AA, Roshandel G, Abdolahi N, et al. [Relation between drinking water hardness and the incidence of esophageal and gastric cancers]. J Gorgan Uni Med Sci. 2009; 11 (3) :76-80. [Article in Persian]
4. Zhang HZ, Jin GF, Shen HB. Epidemiologic differences in esophageal cancer between Asian and Western populations. Chin J Cancer. 2012 Jun; 31(6): 281-86. doi:10.5732/cjc.011.10390
5. O'Reilly S, Forastiere AA. Is surgery necessary with multimodality treatment of oesophageal cancer. Ann Oncol. 1995 Jul; 6(6): 519-21.
6. Coia LR. Esophageal cancer: is esophagectomy necessary? Oncology (Williston Park). 1989 Apr; 3(4): 101-10.
7. Earlam R, Cunha-Melo JR. Oesophogeal squamous cell carcinoms: II. A critical view of radiotherapy. Br J Surg. 1980 Jul; 67(7): 457-61.
8. Earlam R, Cunha-Melo JR. Oesophageal squamous cell carcinoma: I. A critical review of surgery. Br J Surg. 1980 Jun; 67(6): 381-90.
9. Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol. 2010 Jun; 17(6): 1471-4. doi:10.1245/s10434-010-0985-4
10. Jobe LA, Hunter JG, Watson DI. Esophageal carcinoma. In: Brunicardi F, Andersen D, Billiar T, Dunn D, Hunter JG, Matthews J, Pollock RE. Schwartz's Principles of Surgery. 10th ed. New York: McGraw-Hill. 2014; pp: 1004-6.
11. van Hagen P, Hulshof MC, van Lanschot JJ, Steyerberg EW, van Berge Henegouwen MI, Wijnhoven BP, et al. Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med. 2012 May; 366(22): 2074-84. doi:10.1056/NEJMoa1112088
12. Carstens H, Albertsson M, Friesland S, Frykholm AG, Wagenius G, Myrvold HE, Farago I, Stockeld D, et al. A randomized trial of chemoradiotherapy versus surgery alone in patients with resectable esophageal cancer. J Clin Oncol. 2007 Jun; 28(18): 4530. doi:10.1200/jco.2007.25.18_suppl.4530
13. Yu J, Ren R, Sun X, Yin Y, Fu Z. A randomized clinical study of surgery versus radiotherapy in the treatment of resectable esophageal cancer. J Clin Oncol. 2006 Jun; 24(18): 4013. doi:10.1200/jco.2006.24.18_suppl.4013
Send email to the article author


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Basi A, Nikofar A, Azhdarkosh H, Ordoni Aval P, Ordoni Aval Z. Survival rate of patients with esophageal squamous cell carcinoma. J Gorgan Univ Med Sci 2017; 19 (2) :72-76
URL: http://goums.ac.ir/journal/article-1-3080-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 19, Issue 2 (7-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 36 queries by YEKTAWEB 4660
Creative Commons License
This work is licensed under a Creative Commons — Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)