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:: Volume 18, Issue 4 (12-2016) ::
J Gorgan Univ Med Sci 2016, 18(4): 42-48 Back to browse issues page
Effect of endurance swimming training on serum homocysteine level and atherogenic index in rats
MR Kordi1 , MA Borumand2 , Sh Rabbani3 , N Alimoradi Sheikhha4 , A Mazraeh * 5, M Siuf6
1- Associate Professor, Department of Sport Physiology, School of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
2- Associate Professor, Department of Pathology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
3- Veterinary Medicine, Department of Experimental Research, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
4- M.Sc in Exercise Physiology, School of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
5- M.Sc in Exercise Physiology, School of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran , ahmad.mazrae@yahoo.com
6- M.Sc in Exercise Physiology, Department of Physical Education, Firoozabad Branch, Islamic Azad University, Meymand, Iran
Abstract:   (13893 Views)

Background and Objective: Homocysteine and atherogenic index are significant and independent risk factors for cardiovascular diseases. This study was done to determine the effect of 10 weeks endurance swimming training on serum homocysteine level and atherogenic index in rats.

Methods: In this experimental study, 20 adult male Wistar rats (180±20 g) were randomly allocated into control (n=10) and experimental (n=10) groups. Animals in experimental group swam ten weeks of endurance training (5 days a week, for 60 minutes a day) with a 5% body weight load attached to the tail. At the end of 10 weeks and after the last of training session and 12 hours of fasting animals were sacrificed. Blood samples were taken and serum homocysteine level, atherogenic index and
NON-HDL-cholesterol were measured.

Results: Serum homocysteine level, atherogenic index and NON-HDL-cholesterol of animals significantly reduced in the experimental group compared to the controls (P<0.05).

Conclusion: Ten weeks of endurance swimming training with low to moderate intensity improves homocysteine level and atherogenic index in animal model.
Keywords: Endurance swimming training, Homocysteine, Atherogenic index, NON-HDL-cholesterol, Rat
Full-Text [PDF 223 kb] [English Abstract]   (17999 Downloads) |   |   Abstract (HTML)  (1441 Views)  
Type of Study: Original Articles | Subject: Exercise Physiology
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Kordi M, Borumand M, Rabbani S, Alimoradi Sheikhha N, Mazraeh A, Siuf M. Effect of endurance swimming training on serum homocysteine level and atherogenic index in rats. J Gorgan Univ Med Sci 2016; 18 (4) :42-48
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Volume 18, Issue 4 (12-2016) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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