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Evaluation of diagnostic value of sentinel lymph node biopsy in breast cancer
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Abdollahi M1   , Rezaei R2 , Rezaei E3 , Sadeghi R4 , Abdollahi A * 5, Etezadpour M6 , Kalantari MR7 , Afzal Aghaee M8 |
1- Resident of Emergency Medicine, Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2- Assistant Professor of Surgery, Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3- Associate Professor of Plastic Surgery, Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- Associate Professor of Nuclear Medicine, Nuclear Medicine Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5- Associate Professor of Surgery, Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran , abdollahia@mums.ac.ir
6- Resident of Surgery, Endoscopic and Minimally Invasive surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
7- Assistant Professor of Pathology, Department of Pathology, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
8- Assistant Professor of Community Medicine, Department of Biostatistics, Faculty of Health Sciences, Mashhad University of Medical Sciences, Mashhad, Iran |
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Abstract: (29079 Views) |
| Background and Objective: Dissection of the axillary lymph nodes is considered as one of the common measures in management of breast cancer. Edema and limitation in hand movement are accompanied with dissection of axillary lymph nodes. Sentinel lymph node biopsy can be used to evaluate axillary metastasis. This study was carried out to evaluate the diagnostic value of sentinel lymph node biopsy in patients with breast cancer. Materials and Methods: This descriptive study was performed on 30 selected patients with breast cancer less than 5 cm without any involvement of axillary lymph nodes in Ghaem Hospital in Mashhad, North-East of Iran during 2009 -10. Initially, the lymphoscintigraphy was performed. Subsequently, prior, to the surgery, the blue dye as a marker was injected for detecting sentinel lymph node and with the use of probe gamma counter and observing blue color on lymph nodes, the sentinel node was determined and separated. Finally, axillary dissection was performed for removing the lymph nodes of I and II level in all patients. Results: Among 30 patients who were evaluated for sentinel lymph nodes and axillary dissection, false negative were observed only in two cases (6.6 %). The sensitivity rate was determined to be 84.6%. Conclusion: Considering the high success rate of detection of sentinel lymph node and limited false negative cases, sentinel lymph node biopsy is recommended in cases of breast cancer without axillary involvement. |
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| Keywords: Axillary dissection, Breast cancer, Sentinel lymph node biopsy |
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Full-Text [PDF 249 kb]
[English Abstract]
(17820 Downloads)
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Type of Study: Original Articles |
Subject:
Surgery
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Abdollahi M, Rezaei R, Rezaei E, Sadeghi R, Abdollahi A, Etezadpour M, et al . Evaluation of diagnostic value of sentinel lymph node biopsy in breast cancer. J Gorgan Univ Med Sci 2013; 15 (4) :101-105 URL: http://goums.ac.ir/journal/article-1-1873-en.html
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