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:: Volume 12, Issue 1 (3-2010) ::
J Gorgan Univ Med Sci 2010, 12(1): 43-47 Back to browse issues page
Comparison of serum levels of CRP, RF and CIC before and after treatment in hospitalized patients with infective endocarditis in Ahvaz- Iran
Alavi SM (MD) * 1, Ahmadi F (MD) , Nashibi R (MD)
Abstract:   (17493 Views)
Background and Objective: Previous reports on the effect of treatment on the serum immunologic parameters in patients with infective endocarditis are controversial. This study was conducted to asses the serum levels of CRP (C-reactive protein), RF (rheumatoid factor) and CIC (circulatory immune complex) before and after treatment in patients with infective endocarditis. Materials and Methods: In this discriptive study 30 hospitalized patients with infective endocarditis in Razi Hospital in Ahvaz during 2006. Blood samples obtained before and after treatment. 2.5 cc of each sample were used for CRP and RF and remaining 2.5 cc preserved at -20ºC until CIC examination. CRP and RF were measured by using nephlometry and CIC was detected by immundiffusion method. The data were analyzed using SPSS-16 and t-student test. Results: Out of 30 patients, 26 (86.7%) were male. Mean age was 29.53±10.28years. The mean values of CIC, CRP and RF before and after treatment were 0.847, 72.38, 60.45 and 0.80, 44.1, 41.2, respectively. The means of CRP and RF before and after treatment were statistically significant (p<0.05). Conclusion: This study showed that the serum level of CRP and RF reduce after effective treatments because most of the our patients were intravenous drug user, CRP and RF indeces may be useful measurment for treatment evaluation responses to infective endocarditis in these population.
Keywords: Infective endocarditis, CRP, Rheumatoid Factor, Immune complex
Full-Text [PDF 225 kb] [English Abstract]   (14371 Downloads) |   |   Abstract (HTML)  (626 Views)  
Type of Study: Original Articles | Subject: Infectious Medicine
* Corresponding Author Address: Associate Professor, Department of Infectious diseases, Ahvaz University of Medical Sciences, Ahvaz, Iran. alavi.seyedmohammad@yahoo.com


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Alavi SM (MD), Ahmadi F (MD), Nashibi R (MD). Comparison of serum levels of CRP, RF and CIC before and after treatment in hospitalized patients with infective endocarditis in Ahvaz- Iran. J Gorgan Univ Med Sci 2010; 12 (1) :43-47
URL: http://goums.ac.ir/journal/article-1-667-en.html


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Volume 12, Issue 1 (3-2010) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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