[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Indexing Sources::
Editorial Board::
Executive Members::
Articles Archive::
Instruction to Authors::
Peer-Review::
Contact Us::
Site Facilities::
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
:: Volume 11, Issue 1 (3-2009) ::
J Gorgan Univ Med Sci 2009, 11(1): 18-25 Back to browse issues page
Comparison of remifentanil - propofol with remifentanil- thiopental for tracheal intubation without muscle relaxant
Behzad Ahsan (PhD) * 1, Sholeh Shami (MSc) , Karim Nasserii (PhD) , Qader Salehnejad (MSc)
Abstract:   (69719 Views)
Background and Objective: In particular medical situation administration of muscle relaxants following intravenous anesthetics for tracheal intubation may be unnecessary or hazardous. The aim of this study was the comparison of larengoscopy and intubation conditions after induction of anesthesia with propofol or thiopental with remifentanil in the absence of muscle relaxants. Materials and Methods: In a randomized, and double – blind clinical trails, 42 ASA class 1 and 2 patients assigned randomly to propofol 2mg/kg group or thiopental 5mg/kg group. All patients received lidocaine 1.5mg/kg and remifentanil 2.5 µg/kg 30 second before anesthetics administration. Ninety second after administration of the hypnotic agent's, larengoscopy and intubation were attempted. Intubating conditions were assessed as excellent, good, suitable or poor on the basis of mask ventilation, jaw relaxation, vocal cords position and patient's response to intubations and indotracheal tube cuff inflation. The mean arterial pressure and heart rate were measured before and after anesthetic administration, and immidately, 2 and 5 minutes after intubations. Results: 40% of patients in thiopental group and 80% of patients in propofol group showed either excellent or good conditions for larengoscopy and tracheal intubation (P<0.05). Mean arterial pressure and heart rate were decreased more significantly in propofol group in respect to thiopental group (P<0.05). Conclusion: This investigation showed that propofol in combination with remifentanil is better than thiopental for tracheal intubation without muscle relaxants. However, it induces more homodynamic changes.
Keywords: Remifentanil, Propofol, Sodium Thiopental, larengoscopy, Intubation condations
Full-Text [PDF 233 kb] [English Abstract]   (16431 Downloads) |   |   Abstract (HTML)  (770 Views)  
Type of Study: Original Articles | Subject: General
* Corresponding Author Address: behzad_ahsan@muk.ac.ir


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Behzad Ahsan (PhD), Sholeh Shami (MSc), Karim Nasserii (PhD), Qader Salehnejad (MSc). Comparison of remifentanil - propofol with remifentanil- thiopental for tracheal intubation without muscle relaxant. J Gorgan Univ Med Sci 2009; 11 (1) :18-25
URL: http://goums.ac.ir/journal/article-1-457-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 11, Issue 1 (3-2009) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
Persian site map - English site map - Created in 0.04 seconds with 36 queries by YEKTAWEB 4657