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:: Volume 24, Issue 3 (10-2022) ::
J Gorgan Univ Med Sci 2022, 24(3): 86-92 Back to browse issues page
The Impact of Meteorological Factors and Geomagnetic Activity on Occurrence of Stroke in Northeast of Iran
Milad Niknam Azodi1 , Fatemeh Ostvar1 , Abolfazl Amjadipour1 , Sima Besharat2 , Behfar Taziki1 , Fahimeh Abdollahi3 , Seyed Aidin Sajedi * 4
1- General Physician, Clinical Research Development Unit (CRDU), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
2- Medical Doctor, Ph.D in Biomedicine, Associate Professor, Clinical Research Development Unit (CRDU), Golestan Research Center of Gastroenterology & Hepatology (GRCGH), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
3- Pulmonary Fellowship, Clinical Research Development Unit (CRDU), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran. Department of the Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Neurologist, Assistant Professor, Clinical Research Development Unit (CRDU), Sayad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran. , Dr.sajedy@gmail.com
Abstract:   (2546 Views)
Background and Objective: Stroke has a high prevalence and is associated with a high premature mortality rate. Thus, it is important to identify the effective factors in increasing the incidence of stroke. The aim of this study was to investigate the role of seasonal changes and environmental factors in the occurrence of stroke.
Methods: This descriptive-analytical study was done on 3,639 patients including 3,102 (85.3%) with ischemic stroke, 472 (12.9%) with intracerebral hemorrhage and 65 (1.9%) with subarachnoid hemorrhage patients. After measuring environmental factors such as air temperature, air pressure, humidity and geomagnetic field, admission data of stroke patients between 2015-2019 were extracted from the Sayyad Shirazi Hospital information system.
Results: The mean occurrence of intracerebral hemorrhage was highest in winter, especially in January and March, and lowest in summer, especially in July and August. Intracerebral hemorrhage had a positive significant correlation with air pressure (P=0.001, r=0.452) and a negative correlation with ambient temperature (P<0.001, r= - 0.457). Subarachnoid hemorrhage and ischemia were not related to the season or the month. It was also found that ischemic stroke had a significant positive correlation with geomagnetic field fluctuations. Subarachnoid hemorrhage was not associated with any of the variables, but intracerebral hemorrhage was significantly positively associated with air pressure and inversely associated with temperature.
Conclusion: This study illustrated that winter, low temperature, high air pressure and high geomagnetic fluctuations are associated with a higher risk of stroke. Therefore, the underlying physiopathological causes of this relationship should be carefully investigated in future studies.
Keywords: Ischemic Stroke [MeSH], Environment [MeSH], Temperature [MeSH], Geomagnetic Activity , Atmospheric Pressure [MeSH], Humidity [MeSH]
Article ID: Vol24-40
Full-Text [PDF 574 kb]   (6744 Downloads)    
Type of Study: Original Articles | Subject: Neurology
1. Azarpazhooh MR, Etemadi MM, Donnan GA, Mokhber N, Majdi MR, Ghayour-Mobarhan M, et al. Excessive incidence of stroke in Iran: evidence from the Mashhad Stroke Incidence Study (MSIS), a population-based study of stroke in the Middle East. Stroke. 2010 Jan; 41(1): e3-e10. DOI: 10.1161/STROKEAHA.109.559708 [DOI] [PubMed]
2. Hosseini AA, Sobhani-Rad D, Ghandehari K, Benamer HT. Frequency and clinical patterns of stroke in Iran - Systematic and critical review. BMC Neurol. 2010 Aug; 10: 72. DOI: 10.1186/1471-2377-10-72 [DOI] [PubMed]
3. Bahonar A, Khosravi A, Khorvash F, Maracy M, Saadatnia M. Seasonal and Monthly variation in stroke and its subtypes-10 Year Hospital-Based Study. Mater Sociomed. 2017 Jun; 29(2): 119-23. DOI: 10.5455/msm.2017.29.119-123 [DOI] [PubMed]
4. Palmer SJ, Rycroft MJ, Cermack M. Solar and geomagnetic activity, extremely low frequency magnetic and electric fields and human health at the Earth’s surface. Surv Geophys. 2006; 27: 557–95. DOI: 10.1007/s10712-006-9010-7 [Link] [DOI]
5. Toyoda K, Koga M, Yamagami H, Yokota C, Sato S, Inoue M, et al. Seasonal Variations in Neurological Severity and Outcomes of Ischemic Stroke- 5-Year Single-Center Observational Study. Circ J. 2018 Apr; 82(5): 1443-50. DOI: 10.1253/circj.CJ-17-1310 [DOI] [PubMed]
6. Miah AH, Sutradhar SR, Ahmed S, Bhattacharjee M, Alam MK, Bari MA, et al. Seasonal variation in types of stroke and its common risk factors. Mymensingh Med J. 2012 Jan; 21(1): 13-20. [PubMed]
7. Hosininezhad M, Bakhshayesh B, Moaddabi Y, Hatamyan H. [Investigating the Seasonal Pattern of Stroke Incidence and the Association Between Daily Stroke Occurrences and Meteorological Factors]. J Guil Uni Med Sci. 2014; 23(90): 50-58. [Article in Persian] [View at Publisher]
8. Lim JS, Kwon HM, Kim SE, Lee J, Lee YS, Yoon BW. Effects of Temperature and Pressure on Acute Stroke Incidence Assessed Using a Korean Nationwide Insurance Database. J Stroke. 2017 Sep; 19(3): 295-303. DOI: 10.5853/jos.2017.00045 [DOI] [PubMed]
9. Goggins WB, Woo J, Ho S, Chan EY, Chau PH. Weather, season, and daily stroke admissions in Hong Kong. Int J Biometeorol. 2012 Sep; 56(5): 865-72. DOI: 10.1007/s00484-011-0491-9 [DOI] [PubMed]
10. Magalhães R, Silva MC, Correia M, Bailey T. Are stroke occurrence and outcome related to weather parameters? Results from a population-based study in northern portugal. Cerebrovasc Dis. 2011; 32(6): 542-51. DOI: 10.1159/000331473 [DOI] [PubMed]
11. Hong YC, Rha JH, Lee JT, Ha EH, Kwon HJ, Kim H. Ischemic stroke associated with decrease in temperature. Epidemiology. 2003 Jul; 14(4): 473-78. DOI: 10.1097/01.ede.0000078420.82023.e3 [DOI] [PubMed]
12. Sung KC. Seasonal variation of C-reactive protein in apparently healthy Koreans. Int J Cardiol. 2006 Mar; 107(3): 338-42. DOI: 10.1016/j.ijcard.2005.03.045 [DOI] [PubMed]
13. Rosenthal T. Seasonal variations in blood pressure. Am J Geriatr Cardiol. 2004 Sep-Oct; 13(5): 267-72. DOI: 10.1111/j.1076-7460.2004.00060.x [DOI] [PubMed]
14. Visscher TL, Seidell JC. Time trends (1993-1997) and seasonal variation in body mass index and waist circumference in the Netherlands. Int J Obes Relat Metab Disord. 2004 Oct; 28(10): 1309-16. DOI: 10.1038/sj.ijo.0802761 [DOI] [PubMed]
15. Ma Y, Olendzki BC, Li W, Hafner AR, Chiriboga D, Hebert JR, et al. Seasonal variation in food intake, physical activity, and body weight in a predominantly overweight population. Eur J Clin Nutr. 2006 Apr; 60(4): 519-28. DOI: 10.1038/sj.ejcn.1602346 [DOI] [PubMed]
16. Goldstein LB, Adams R, Alberts MJ, Appel LJ, Brass LM, Bushnell CD, et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: the American Academy of Neurology affirms the value of this guideline. Stroke. 2006 Jun; 37(6): 1583-633. DOI: 10.1161/01.STR.0000223048.70103.F1 [DOI] [PubMed]
17. Fischer T, Johnsen SP, Pedersen L, Gaist D, Sørensen HT, Rothman KJ. Seasonal variation in hospitalization and case fatality of subarachnoid hemorrhage - a nationwide danish study on 9,367 patients. Neuroepidemiology. 2005; 24(1-2): 32-37. DOI: 10.1159/000081047 [DOI] [PubMed]
18. Feigin VL, Anderson CS, Anderson NE, Broad JB, Pledger MJ, Bonita R. Is there a temporal pattern in the occurrence of subarachnoid hemorrhage in the southern hemisphere? Pooled data from 3 large, population-based incidence studies in Australasia, 1981 to 1997. Stroke. 2001 Mar; 32(3): 613-19. DOI: 10.1161/01.str.32.3.613 [DOI] [PubMed]
19. Wang Y, Levi CR, Attia JR, D'Este CA, Spratt N, Fisher J. Seasonal variation in stroke in the Hunter Region, Australia: a 5-year hospital-based study, 1995-2000. Stroke. 2003 May; 34(5): 1144-50. DOI: 10.1161/01.STR.0000067703.71251.B6 [DOI] [PubMed]
20. Gurfinkel' IuI, Liubimov VV, Oraevskiĭ VN, Parfenova LM, Iur'ev AS. [The effect of geomagnetic disturbances in capillary blood flow in ischemic heart disease patients]. Biofizika. 1995 Jul-Aug; 40(4): 793-99. [Article in Russian] [PubMed]
21. Stoupel E, Martfel JN, Rotenberg Z. Paroxysmal atrial fibrillation and stroke (cerebrovascular accidents) in males and females above and below age 65 on days of different geomagnetic activity levels. J Basic Clin Physiol Pharmacol. 1994 Jul-Dec; 5(3-4): 315-29. DOI: 10.1515/jbcpp.1994.5.3-4.315 [DOI] [PubMed]
22. Otsuka K, Cornélissen G, Weydahl A, Holmeslet B, Hansen TL, Shinagawa M, et al. Geomagnetic disturbance associated with decrease in heart rate variability in a subarctic area. Biomed Pharmacother. 2001; 55 Suppl 1: 51s-56s. DOI: 10.1016/s0753-3322(01)90005-8 [DOI] [PubMed]
23. Ghione S, Mezzasalma L, Del Seppia C, Papi F. Do geomagnetic disturbances of solar origin affect arterial blood pressure? J Hum Hypertens. 1998 Nov; 12(11): 749-54. DOI: 10.1038/sj.jhh.1000708 [DOI] [PubMed]
24. Watanabe Y, Cornélissen G, Halberg F, Otsuka K, Ohkawa SI. Associations by signatures and coherences between the human circulation and helio- and geomagnetic activity. Biomed Pharmacother. 2001; 55 Suppl 1: 76s-83s. DOI: 10.1016/s0753-3322(01)90008-3 [DOI] [PubMed]
25. Stoupel E, Keret R, Assa S. Secretion of growth hormone, prolactin and corticosteroids during different levels of geomagnetic activity. Neuroendocrinology Letters. 1983; 5(6): 365-68. [Link]
26. Cornélissen G, Halberg F, Breu T, Syutkina EV, Baevsky R, Weydahal A, et al. Non-photic solar associations of heart rate variability and myocardial infarction. Journal of Atmospheric and Solar-Terrestrial Physics. 2002; 64(5-6): 707-20. DOI: 10.1016/S1364-6826(02)00032-9 [Link] [DOI]
27. Stoupel E, Abramson E, Sulkes J, Martfel J, Stein N, Handelman M, et al. Relationship between suicide and myocardial infarction with regard to changing physical environmental conditions. Int J Biometeorol. 1995 May; 38(4): 199-203. DOI: 10.1007/BF01245389 [DOI] [PubMed]
28. Feigin VL, Parmar PG, Barker-Collo S, Bennett DA, Anderson CS, Thrift AG, et al. Geomagnetic storms can trigger stroke: evidence from 6 large population-based studies in Europe and Australasia. Stroke. 2014 Jun; 45(6): 1639-45. DOI: 10.1161/STROKEAHA.113.004577 [DOI] [PubMed]
29. Dorman LI, Ptitsyna NG, Villoresi G, Kasinsky VV, Lyakhov NN, Tyasto MI. Space storms as natural hazards. Adv Geosci. 2008; 14: 271-75. DOI: 10.5194/adgeo-14-271-2008 [Link] [DOI]
30. Pikin DA, Gurfinkel' IuI, Oraevskiĭ VN. [Effect of geomagnetic disturbances on the blood coagulation system in patients with ischemic heart disease and prospects for correction with medication]. Biofizika. 1998 Jul-Aug; 43(4): 617-22. [Article in Russian] [PubMed]
31. Zhong H, Shu Z, Zhou Y, Lu Y, Yi B, Tang X, et al. Seasonal Effect on Association between Atmospheric Pollutants and Hospital Emergency Room Visit for Stroke. J Stroke Cerebrovasc Dis. 2018 Jan; 27(1): 169-76. DOI: 10.1016/j.jstrokecerebrovasdis.2017.08.014 [DOI] [PubMed]
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Niknam Azodi M, Ostvar F, Amjadipour A, Besharat S, Taziki B, Abdollahi F et al . The Impact of Meteorological Factors and Geomagnetic Activity on Occurrence of Stroke in Northeast of Iran. J Gorgan Univ Med Sci 2022; 24 (3) :86-92
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Volume 24, Issue 3 (10-2022) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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