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:: Volume 10, Issue 3 (10-2008) ::
J Gorgan Univ Med Sci 2008, 10(3): 32-37 Back to browse issues page
Comparison of serum leptin and thyroid hormones levels in obese and non-obese women
Seyyed Mahdi Ahmadi (MSc) * 1, Mohammad Hasan Eftekhari (PhD) , Farshad Amirkhizi (MSc) , Mahmood Soveid (MD) , Mina Jahri (BSc) , Sareh Keshavarzi (MSc)
Abstract:   (18621 Views)
Background and Objective: Many factors are known to be involved in a number of human pathologies of obesity including serum leptin and thyroid hormones levels. The purpose of this study was to compare the serum levels of leptin and thyroid hormones in obese and non-obese women, in Shiraz-Iran during 2006. Materials and Methods: In this case- control study, 35 women with BMI≥30 Kg/m2 recruited as an obese group (Case group) and 35 women with healthy BMI (BMI<25 Kg/m2) were selected as a control group. General information data were gathered from each sample using questionnaires and face-to-face interviews. Body weight, height, waist and hip circumferences were measured and BMI, WHR and percent of body fat (%TBF) were calculated for each subject. Venous blood samples were drawn from subjects and serum was separated to determine the concentrations of serum leptin and thyroid hormones (T4, T3 and TSH) levels. Results: Mean serum concentration of leptin was significantly higher in obese group than control group (p<0.001). Serum leptin levels positively correlated to anthropometric indices (BMI, WHR, %TBF). No significant difference was observed between obese and non-obese groups in serum thyroid hormones concentration. Serum leptin levels positively related to serum T3 levels (P<0.05). Conclusion: This study indicated that obese women had higher leptin levels compared to non-obese. The interaction between thyroid hormone in particular T3 and leptin can be one of the reason for increasing the serum leptin level among obse women.
Keywords: Obesity, Leptin, Thyroid hormones, Women
Full-Text [PDF 225 kb] [English Abstract]   (15297 Downloads)    
Type of Study: Original Articles | Subject: General
* Corresponding Author Address: ahmadi.nutrition@gmail.com


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Seyyed Mahdi Ahmadi (MSc), Mohammad Hasan Eftekhari (PhD), Farshad Amirkhizi (MSc), Mahmood Soveid (MD), Mina Jahri (BSc), Sareh Keshavarzi (MSc). Comparison of serum leptin and thyroid hormones levels in obese and non-obese women. J Gorgan Univ Med Sci 2008; 10 (3) :32-37
URL: http://goums.ac.ir/journal/article-1-390-en.html


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Volume 10, Issue 3 (10-2008) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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