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:: Volume 22, Issue 4 (12-2020) ::
J Gorgan Univ Med Sci 2020, 22(4): 63-69 Back to browse issues page
Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice
Mahshid Golkar Moghaddam1 , Saeedeh Zafar Balanejad * 2, Jina Khayatzadeh3
1- M.Sc in Genetics, Department of Biology, Faculty of Basic Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
2- Assistant Professor, Department of Biology, Faculty of Basic Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran. , mojgan_zafar@yahoo.com
3- Assistant Professor, Department of Biology, Faculty of Basic Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Abstract:   (7098 Views)
Background and Objective: The increasing usage of cell phones, have raised concerns about the potential effects of these waves on the health of individuals. In the present research the effect of mobile phone radiation on the expression of DAZL gene in BALB/c mice were studied.
Methods: 18 male mice were divided into three groups: Control, sham-exposed and experimental. Experimental mice were exposed to mobile waves for 2 hours daily, during 3 weeks. After 3 weeks, the testes were excised and RNA extraction and Real-Time PCR were performed. Sperm counts in deferen channel and the study of sperm motility in epididymis were done.
Results: The percentage of non-progressive sperm motility significantly increased in experimental group in compared to control group (P<0.05).The level of DAZL gene expression in the experimental group was significantly lower than the control group (P<0.05). Weight of the testis, percentage of live sperm, percentage of rapid progressive sperm motility and percentage of slow progressive sperm motility non-significantly reduced in experimental group in comparison with controls.
Conclusion: Exposure to cell phone waves for 21 days and 2 hours a day impairs spermatogenesis by reducing the quality and motility of sperm and also reduction of expression of DAZL gene.
Keywords: Infertility [MeSH], Cell Phone [MeSH], DAZL Gene
Article ID: Vol22-55
Full-Text [PDF 381 kb]   (11843 Downloads)    
Type of Study: Original Articles | Subject: Reproduction & Infertility
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Golkar Moghaddam M, Zafar Balanejad S, Khayatzadeh J. Effect of cell phone radiation on sperm characteristics and DAZL gene expression in BALB/c mice. J Gorgan Univ Med Sci 2020; 22 (4) :63-69
URL: http://goums.ac.ir/journal/article-1-3650-en.html


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Volume 22, Issue 4 (12-2020) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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