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:: Volume 22, Issue 1 (3-2020) ::
J Gorgan Univ Med Sci 2020, 22(1): 17-26 Back to browse issues page
Effect of high intensity interval training and supplementation of omega-3 on serum levels of brain derived neurotrophic factor and resting blood pressure of inactive male students
Sajad Karimipour1 , Shila Nayebifar * 2, Mahmood Fazel Bakhsheshi3
1- M.A in Exercise Physiology, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran.
2- Assistant Professor in Exercise Physiology, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran , shila_nayebifar@ped.usb.ac.ir
3- Assistant Professor in Sport Management, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran.
Abstract:   (7348 Views)
Background and Objective: Researches has shown that exercise and nutrition exercises can have a different effect on serum Brain Derived Neurotrophic Factor (BDNF( levels and resting blood pressure in young people. This study was done to determine the effect of a period of High Intensity Interval Training (HIIT) with omega-3 supplementation on the serum levels of BDNF and resting blood pressure in inactive male students.
Methods: In this clinical trail study, 32 non-athlete male students were randomly divided into control, supplements, training and training + supplement. Subjects in supplementary group were received daily (2000 mg) of omega-3 capsules. The training groups were also subjected to HIIT training for 6 weeks. The training + Supplemental group also included a combination of the same training program were associated with omega-3 supplementation. BDNF levels were measured by ELISA method 24 and 48 hours perior the exercise protocol and after the last training session. Blood pressure disturbances were also evaluated at the same time and before blood sampling according to the recommendations of the British Heart Association.
Results: The serum levels of BDNF in the group after 6 weeks in the training + supplementation group and the training group increased significantly compared to the pre-test values (P˂0.05). Also, a significant difference between-group training + supplementation group and training, supplementation and control groups were observed (P˂0.05). Systolic and diastolic blood pressures were significantly reduced in training + supplementary, training and supplementation groups compared to pretest values (P˂0.05). A significant reduction in systolic blood pressure in the training + supplementation group was observed compared to supplemental and control groups (P˂0.05).
Conclusion: HIIT combined with supplementation with omega-3 supplementation improved the BDNF serum level and reducing resting blood pressure in inactive male students.

Keywords: High-intensity interval training, Omega-3, Brain-derived neurotrophic factor, Blood pressure
Article ID: Vol22-03
Full-Text [PDF 288 kb]   (12443 Downloads)    
Type of Study: Original Articles | Subject: Physiology - Pharmacology
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Karimipour S, Nayebifar S, Fazel Bakhsheshi M. Effect of high intensity interval training and supplementation of omega-3 on serum levels of brain derived neurotrophic factor and resting blood pressure of inactive male students. J Gorgan Univ Med Sci 2020; 22 (1) :17-26
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Volume 22, Issue 1 (3-2020) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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