[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
About the Journal
Aims and Scope
Content Coverage
Conflict of Interest
Publication Ethics
Editorial Board::
Executive Members::
Instruction to Authors::
Peer Review::
Articles Archive::
Current Issue
All Issues
Indexing Databases::
Contact Us::
Contact Us
Contact Form
Site Facilities::
Search contents
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
:: Volume 20, Issue 3 (10-2018) ::
J Gorgan Univ Med Sci 2018, 20(3): 104-109 Back to browse issues page
Prevalence of abnormal liver enzymes and pregnancy outcome in women admitted to Sayyad-e-Shirazi hospital Gorgan- north of Iran (2015)
Sarah Ostovar1 , Alireza Norouzi * 2, Elham Mobasheri3 , Gholamreza Roshandel4 , Sima Besharat4
1- Medical Student, Golestan Research Center of Gastroentrology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
2- Assistant Professor, Golestan Research Center of Gastroentrology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran. norouzi54@gmail.com , norouzi54@gmail.com
3- Associate Professor, Gorgan Congenital Malformations Research Center, Golestan University of Medical Sciences, Gorgan, Iran
4- Assistant Professor, Golestan Research Center of Gastroentrology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
Abstract:   (9847 Views)
Background and Objective: Liver enzyme tests are usually normal or slightly increased during pregnancy. Abnormal liver enzyme tests are seen in 3% of pregnancies and should be evaluated immediately. Early detection and timely treatment is the key to successful treatment. This study was carried out to determine the prevalence of abnormal liver enzymes and pregnancy outcome in women admitted to Sayyad-e-Shirazi hospital in Gorgan-north of Iran.
Methods: This descriptive, cross-sectional study was carried out on 73 hospitalized pregnant women out of 6680 pregnant women in the Sayyad Shirazi hospital, in north of Iran during April to September 2015. Clinical information was including laboratory tests, final diagnosis and complications postpartum of 73 women with impaired liver enzymes.
Results: The most common cause of abnormal liver enzymes were pre-eclampsia in pregnant women (16 patients 21.9%) which occured in the third trimester. HELLP syndrome was observed in 9 (12.3%) of patients which occurred in the third trimester. Also in 3 cases (4.1%) eclampsia was reported in the third trimester.
Conclusion: Due to the high incidence of pre-eclampsia and HELLP syndrome in women with impaired liver enzymes, careful examination of patients, especially in the third trimester of pregnancy is essential.
Keywords: Liver enzymes, HELLP syndrome, Pre-eclampsia, Eclampsia, Iran
Full-Text [PDF 240 kb] [English Abstract]   (14277 Downloads) |   |   Abstract (HTML)  (326 Views)  
Type of Study: Original Articles | Subject: Internal Medicine
* Corresponding Author Address: Assistant Professor, Golestan Research Center of Gastroentrology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran. norouzi54@gmail.com
References
1. Angel García AL. Effect of pregnancy on pre-existing liver disease physiological changes during pregnancy. Ann Hepatol. 2006 Jul-Sep; 5(3): 184-86.
2. Kondrackiene J, Kupcinskas L. Liver diseases unique to pregnancy. Medicina (Kaunas). 2008; 44(5): 337-45.
3. Hepburn IS, Schade RR. Pregnancy-associated liver disorders. Dig Dis Sci. 2008 Sep; 53(9): 2334-58. doi:10.1007/s10620-007-0167-9
4. Than NN, Neuberger J. Liver abnormalities in pregnancy. Best Pract Res Clin Gastroenterol. 2013 Aug; 27(4): 565-75. doi:10.1016/j.bpg.2013.06.015
5. Guntapulli SR, Steingrub J. Hepatic disease and pregnancy: an overwiew of diagnosis and management. Critical Care Medicine. 2005 Oct; 33(10): S332-9. doi:10.1097/01.CCM.0000182555.39644.7F
6. Panther E, Blum HE. [Liver diseases in pregnancy]. Dtsch Med Wochenschr. 2008 Oct; 133(44): 2283-87. doi:10.1055/s-0028-1091273. [Article in German]
7. Mufti AR, Reau N. Liver disease in pregnancy. Clin Liver Dis. 2012 May; 16(2): 247-69. doi:10.1016/j.cld.2012.03.011
8. Dsouza AS, Gupta G, Sandeep SG, Katumalla FS, Goyal S. Maternal and fetal outcome in liver diseases of pregnancy - A tertiary hospital experience. International Journal of Scientific and Research Publications. 2015; 5(9): 1-4.
9. Ahmed KT, Almashhrawi AA, Rahman RN, Hammoud GM, Ibdah JA. Liver diseases in pregnancy: Diseases unique to pregnancy. World J Gastroenterol. 2013; 19(43): 7639-46. doi:10.3748/wjg.v19.i43.7639
10. Rathi U, Bapat M, Rathi P, Abraham P. Effect of liver disease on maternal and fetal outcome--a prospective study. Indian J Gastroenterol. 2007 Mar-Apr; 26(2): 59-63.
11. Ghulmiyyah L, Sibai B. Maternal mortality from preeclampsia/eclampsia. Semin Perinatol. 2012 Feb; 36(1): 56-9. doi:10.1053/j.semperi.2011.09.011
Send email to the article author

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Ostovar S, Norouzi A, Mobasheri E, Roshandel G, Besharat S. Prevalence of abnormal liver enzymes and pregnancy outcome in women admitted to Sayyad-e-Shirazi hospital Gorgan- north of Iran (2015). J Gorgan Univ Med Sci 2018; 20 (3) :104-109
URL: http://goums.ac.ir/journal/article-1-3460-en.html
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 20, Issue 3 (10-2018) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
Persian site map - English site map - Created in 0.04 seconds with 36 queries by YEKTAWEB 4660
Creative Commons License
This work is licensed under a Creative Commons — Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)