[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Editorial Board::
Executive Members::
Instruction to Authors::
Peer Review::
Articles Archive::
Indexing Databases::
Contact Us::
Site Facilities::
::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
:: Volume 21, Issue 2 (7-2019) ::
J Gorgan Univ Med Sci 2019, 21(2): 77-82 Back to browse issues page
Pervalance of Helicobacter pylori stool antigen in children with chronic abdominal pain
Mohammad Salehi1 , Mohammad Sobhani Shahmirzadi * 2, Leila Barati3
1- General Practitioner, Neonatal and Children’s Health Research Center, Taleghani Children’s Center, Golestan University of Medical Sciences, Gorgan, Iran
2- Pediatric Gastroenterologist, Associate Professor, Neonatal and Children’s Health Research Center, Taleghani Children’s Center, Golestan University of Medical Sciences, Gorgan, Iran , sobhani_shahmirzadi@yahoo.com
3- Pediatrician, Assistant Professor, Neonatal and Children’s Health Research Center, Taleghani Children’s Center, Golestan University of Medical Sciences, Gorgan, Iran
Abstract:   (8961 Views)

Background and Objective: Chronic and recurrent abdominal pain affect about 7-20% of children in school age, and it is responsible for 2-4% of children's medical referrals. Helicobacter pylori infection in children can cause gastrointestinal problems in childhood, and the lack of treatment and eradication can lead to serious complications. This study was done to evaluate the prevalence of Helicobacter pylori ELISA stool antigen in children with chronic abdominal pain.

Methods: In this case control study, 33 children with chronic abdominal pain and 30 normal children were evaluated. The stool was tested by ELISA method to evaluate Helicobacter pylori antigen.

Results: 15.2% of chidern in the chronic abdominal pain group were positive for Helicobacter pylori. No positive case was found among control group. This difference between case and control groups was significant (P<0.05).

Conclusion: Considering the high prevalence of Helicobacter pylori antigen in children with chronic abdominal pain, it is suggested that children with chronic abdominal pain without a definite cause screened for Helicobacter pylori infection.

Keywords: Helicobacter pylori, Chronic abdominal pain, Children, Helicobacter pylori stool antigen
Full-Text [PDF 201 kb]   (17935 Downloads)    
Type of Study: Original Articles | Subject: Pediatric
References
1. Bandyopadhyay A, Mondal PK. Recurrent abdominal pain in children and adolescents: a hospital based study. Int J Contemp Pediatr. 2017; 4(3): 726-28. http://dx.doi.org/10.18203/2349-3291.ijcp20170924
2. Dhroove G, Chogle A, Saps M. A million-dollar work-up for abdominal pain: is it worth it? J Pediatr Gastroenterol Nutr. 2010 Nov; 51(5): 579-83. doi: 10.1097/MPG.0b013e3181de0639
3. Youssef NN, Atienza K, Langseder AL, Strauss RS. Chronic abdominal pain and depressive symptoms: analysis of the national longitudinal study of adolescent health. Clin Gastroenterol Hepatol. 2008 Mar; 6(3): 329-32. doi: 10.1016/j.cgh.2007.12.019
4. Campo JV, Di Lorenzo C, Chiappetta L, Bridge J, Colborn DK, Gartner JC Jr, et al. Adult outcomes of pediatric recurrent abdominal pain: do they just grow out of it? Pediatrics. 2001 Jul; 108(1): E1.
5. Quek SH. Recurrent abdominal pain in children: a clinical approach. Singapore Med J. 2015 Mar; 56(3): 125-28.
6. Ozbey G, Hanafiah A. Epidemiology, diagnosis, and risk factors of Helicobacter pylori infection in children. Euroasian J Hepatogastroenterol. 2017 Jan-Jun; 7(1): 34-39. doi: 10.5005/jp-journals-10018-1208
7. Perez-Perez GI, Rothenbacher D, Brenner H. Epidemiology of Helicobacter pylori infection. Helicobacter. 2004; 9(Suppl 1): 1-6. doi: 10.1111/j.1083-4389.2004.00248.x
8. Moosazadeh M, Lankarani KB, Afshari M. Meta-analysis of the prevalence of Helicobacter pylori infection among children and adults of Iran. Int J Prev Med. 2016; 7: 48. doi: 10.4103/2008-7802.177893
9. Pacifico L, Anania C, Osborn JF, Ferraro F, Chiesa C. Consequences of Helicobacter pylori infection in children. World J Gastroenterol. 2010 Nov; 16(41): 5181-94.
10. Bourke B, Ceponis P, Chiba N, Czinn S, Ferraro R, Fischbach L, et al. Canadian Helicobacter Study Group Consensus Conference: Update on the approach to Helicobacter pylori infection in children and adolescents--an evidence-based evaluation. Can J Gastroenterol. 2005 Jul; 19(7): 399-408.
11. Mansour MM, Al Hadidi KhM, Omar MA. Helicobacter pylori and recurrent abdominal pain in children: is there any relation? Trop Gastroenterol. 2012 Jan-Mar; 33(1): 55-61.
12. Iranikhah A, Ghadir MR, Sarkeshikian S, Saneian H, Heiari A, Mahvari M. Stool antigen tests for the detection of Helicobacter pylori in children. Iran J Pediatr. 2013; 23(2): 138-42.
13. Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2016 May; 150(6): 1456-68.e2. https://doi.org/10.1053/j.gastro.2016.02.015
14. Jones NL, Koletzko S, Goodman K, Bontems P, Cadranel S, Casswall T, et al. Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016). J Pediatr Gastroenterol Nutr. 2017 Jun; 64(6): 991-1003. doi: 10.1097/MPG.0000000000001594
15. Punhal M, Malik Q, Iqbal A. Helicobacter Pylori infection in children presenting with recurrent abdominal pain. Pak Armed Forces Med J. 2016; 66(2): 266-69.
16. Jang KM, Choe B-H, Choe JY, Hong SJ, Park HJ, Chu M, et al. Changing prevalence of Helicobacter pylori infections in Korean children with recurrent abdominal pain. Pediatr Gastroenterol Hepatol Nutr. 2015 May; 18(1): 10-16. doi: 10.5223/pghn.2015.18.1.10
17. Bin Mohanna MA, Al-Zubairi LM, Sallam AK. Prevalence of Helicobacter pylori and parasites in symptomatic children examined for Helicobacter pylori antibodies, antigens, and parasites in Yemen. Saudi Med J. 2014 Nov; 35(11): 1408-11.
18. Salih KMA, Elfaki OA, Hamid YHM, Eldouch WMA, Diab M, Abdelgadir SO. Prevalence of Helicobacter Pylori among Sudanese children admitted to a specialized children hospital. Sudan J Paediatr. 2017; 17(1): 14-18.
19. Zohoori D, Ardakani OS. The association between Helicobacter Pylori infection and abdominal pain in children aged 2-10 years. Galen Medical Journal. 2016; 5(1): 19-24.
20. Telmesani AM. Helicobacter pylori: prevalence and relationship with abdominal pain in school children in Makkah City, western Saudi Arabia. Saudi J Gastroenterol. 2009 Apr; 15(2): 100-103. doi: 10.4103/1319-3767.45359
21. Ozen H, Dinler G, Akyön Y, Koçak N, Yüce A, Gürakan F. Helicobacter pylori infection and recurrent abdominal pain in Turkish children. Helicobacter. 2001 Sep; 6(3): 234-38.
22. Chiu NC, Lin CY, Chi H, Yeung CY, Ting WH, Chan WT, et al. Helicobacter pylori infection is not associated with failure to thrive: a case control study. Ther Clin Risk Manag. 2017 Feb; 13: 273-78. doi: 10.2147/TCRM.S123148
23. Thakkar K, Chen L, Tessier ME, Gilger MA. Outcomes of children after esophagogastroduodenoscopy for chronic abdominal pain. Clin Gastroenterol Hepatol. 2014; 12(6): 963-69. doi: 10.1016/j.cgh.2013.08.041
24. Masoodpoor N, Darakhshan, Sheikhvatan M. Helicobacter pylori infection in Iranian children with recurrent abdominal pain. Trop Gastroenterol. 2008 Oct-Dec; 29(4): 221-23.
25. Gold BD, Gilger MA, Czinn SJ. New diagnostic strategies for detection of Helicobacter pylori infection in pediatric patients. Gastroenterol Hepatol (N Y). 2014 Dec; 10(12 Suppl 7): 1-19.
Send email to the article author


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Salehi M, Shahmirzadi M S, Barati L. Pervalance of Helicobacter pylori stool antigen in children with chronic abdominal pain. J Gorgan Univ Med Sci 2019; 21 (2) :77-82
URL: http://goums.ac.ir/journal/article-1-3341-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 21, Issue 2 (7-2019) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
Persian site map - English site map - Created in 0.04 seconds with 36 queries by YEKTAWEB 4660
Creative Commons License
This work is licensed under a Creative Commons — Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)