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:: Volume 9, Issue 4 (12-2007) ::
J Gorgan Univ Med Sci 2007, 9(4): 31-35 Back to browse issues page
The effect of lidocaine in reducing pain following Propofol injection (Lipuro%1)
Kazem Kazemnejad * 1, Siyamak Rajaii , Arazberdi Ghorchaii , Mohammad Hosein Taziki
Abstract:   (16616 Views)

Background & Objective: Propofol is one of the latest anesthetic agent which has many advantages with few side effects in patients. One of the application problems of this drug is pain at the time of injection. Several methods are investigated to reduce the pain, and one of them is the application of Lidocaine together with Propofol.

Materials & Methods: This randomized clinical trial study was done in 5th Azar teaching during 2007. 272 patients were selected randomly between age of 15-55 years with ASA Class I,II who were the candidates of elective surgery. We injected  Fresenius %1 to the first group with 91 patients, Lipuro %1 to the second group with 90 patients and Propofol drug Lipuro %1 mixed with 20 mg Lidocaine (2 ml of Lidocaine %1) to the third group with 91 patients. Injections was carid out on the supenlial vein of dorsal hand. Patients were asked about the severity of pain at the time of injection, 5-10 seconds after %25 of anesthetic induction doze. Data analyzed with using SPSS software and Chi-Squre test.

Results: The rate (incidence) of pain (Score 1-3) has been 63.91 (%69.2) in the first group, 50.90 (%55.6), and 22.9 (24.2%) in the third group in which there is a significant difference (P<0.001). Moderate and sever intensity of pain (Score 2.3) was 42.91 (46%) For the first group, 18.90 (20%) for the second group and 2.91 (2.2%) for the third group (P<0.001).

Conclusion: On the basis of this study, it is recommended to use lidocaine, at the time of injection, to reduce pain.

Keywords: Pain, Propofol, Lidocaine
Full-Text [PDF 229 kb] [English Abstract]   (22003 Downloads)    
Type of Study: Original Articles | Subject: General
* Corresponding Author Address: kazemnejad1341@yahoo.com


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Kazemnejad K, Rajaii S, Ghorchaii A, Taziki M H. The effect of lidocaine in reducing pain following Propofol injection (Lipuro%1). J Gorgan Univ Med Sci 2007; 9 (4) :31-35
URL: http://goums.ac.ir/journal/article-1-316-en.html


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Volume 9, Issue 4 (12-2007) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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