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:: Volume 19, Issue 2 (7-2017) ::
J Gorgan Univ Med Sci 2017, 19(2): 72-76 Back to browse issues page
Survival rate of patients with esophageal squamous cell carcinoma
A Basi1 , AR Nikofar2 , H Azhdarkosh3 , P Ordoni Aval * 4, Z Ordoni Aval5
1- Associate Professor, Hematologist and Oncologist, Iran University of Medical Sciences, Tehran, Iran
2- Assistant Professor, Radiotherapist, Iran University of Medical Sciences, Tehran, Iran
3- Assistant Professor, Gastroenterologist, Iran University of Medical Sciences, Tehran, Iran
4- Resident in Internal Medicine, Iran University of Medical Sciences, Tehran, Iran , parviz_ordoni@yahoo.com
5- Midwifer, Golestan University of Medical Sciences, Gorgan, Iran
Abstract:   (11382 Views)

Background and Objective: Squamous carcinoma accounts for the majority of esophageal carcinoma worldwide. This study was done to evaluate the survival rate of patients with esophageal cancer in Iran.

Methods: This historical cohort study was carried outon 105 patients with esophageal squamous cell carcinoma whom admitted to Firoozgar hospital in Tehran, Iran during 2009-14. Patients with esophageal squamous cell carcinoma were treated with chemoradiation either with or without surgery.

Results: The mean age of patients was 63 years. Frequency of esophageal cancer in both sexes in the age group 51-60 years was higher than other groups. 5-year survival in patients with esophageal cancer treated with chemoradiation without surgery was 9.5% and in patients treated with chemoradiation with surgery was 31.7 % (P<0.05). One-year, three-year and five-year survival rate in patients were treated with chemoradiation with or without surgery was 68.5%, 38% and 22.8%, respectively.

Conclusion: The survival rate of patients with esophageal cancer is very low, but the treatment with chemoradiation with surgery can increase life expectancy of patients.

Keywords: Esophagus, Squamous cell carcinoma, Survival, Chemotherapy, Chemoradiation, Surgery
Full-Text [PDF 221 kb] [English Abstract]   (15408 Downloads) |   |   Abstract (HTML)  (1318 Views)  
Type of Study: Original Articles | Subject: Oncology
References
1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013 Jan; 63(1): 11-30. doi:10.3322/caac.21166
2. Malekzadeh R, Semnani Sh, Sadjadi A. [Esophageal Cancer in Iran]. Govaresh. 2008; 13(1): 25-34. [Article in Persian]
3. Semnani Sh, Besharat S, Arabali A, Kestkar AA, Roshandel G, Abdolahi N, et al. [Relation between drinking water hardness and the incidence of esophageal and gastric cancers]. J Gorgan Uni Med Sci. 2009; 11 (3) :76-80. [Article in Persian]
4. Zhang HZ, Jin GF, Shen HB. Epidemiologic differences in esophageal cancer between Asian and Western populations. Chin J Cancer. 2012 Jun; 31(6): 281-86. doi:10.5732/cjc.011.10390
5. O'Reilly S, Forastiere AA. Is surgery necessary with multimodality treatment of oesophageal cancer. Ann Oncol. 1995 Jul; 6(6): 519-21.
6. Coia LR. Esophageal cancer: is esophagectomy necessary? Oncology (Williston Park). 1989 Apr; 3(4): 101-10.
7. Earlam R, Cunha-Melo JR. Oesophogeal squamous cell carcinoms: II. A critical view of radiotherapy. Br J Surg. 1980 Jul; 67(7): 457-61.
8. Earlam R, Cunha-Melo JR. Oesophageal squamous cell carcinoma: I. A critical review of surgery. Br J Surg. 1980 Jun; 67(6): 381-90.
9. Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol. 2010 Jun; 17(6): 1471-4. doi:10.1245/s10434-010-0985-4
10. Jobe LA, Hunter JG, Watson DI. Esophageal carcinoma. In: Brunicardi F, Andersen D, Billiar T, Dunn D, Hunter JG, Matthews J, Pollock RE. Schwartz's Principles of Surgery. 10th ed. New York: McGraw-Hill. 2014; pp: 1004-6.
11. van Hagen P, Hulshof MC, van Lanschot JJ, Steyerberg EW, van Berge Henegouwen MI, Wijnhoven BP, et al. Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med. 2012 May; 366(22): 2074-84. doi:10.1056/NEJMoa1112088
12. Carstens H, Albertsson M, Friesland S, Frykholm AG, Wagenius G, Myrvold HE, Farago I, Stockeld D, et al. A randomized trial of chemoradiotherapy versus surgery alone in patients with resectable esophageal cancer. J Clin Oncol. 2007 Jun; 28(18): 4530. doi:10.1200/jco.2007.25.18_suppl.4530
13. Yu J, Ren R, Sun X, Yin Y, Fu Z. A randomized clinical study of surgery versus radiotherapy in the treatment of resectable esophageal cancer. J Clin Oncol. 2006 Jun; 24(18): 4013. doi:10.1200/jco.2006.24.18_suppl.4013
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Basi A, Nikofar A, Azhdarkosh H, Ordoni Aval P, Ordoni Aval Z. Survival rate of patients with esophageal squamous cell carcinoma. J Gorgan Univ Med Sci 2017; 19 (2) :72-76
URL: http://goums.ac.ir/journal/article-1-3080-en.html


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Volume 19, Issue 2 (7-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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