[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Journal Information::
Indexing Sources::
Editorial Board::
Executive Members::
Articles Archive::
Instruction to Authors::
Contact Us::
Site Facilities::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
:: Volume 19, Issue 1 (3-2017) ::
J Gorgan Univ Med Sci 2017, 19(1): 54-66 Back to browse issues page
Association between healthy lifestyle score and upper gastrointestinal disorders in Iranian adults
P Saneei1 , M Hajishafiee2 , A Esmaillzadeh * 3, A Hassanzadeh Keshteli4 , HR Roohafza5 , H Afshar5 , A Feizi6 , P Adibi7
1- Ph.D in Nutrition, Food Security Research Center, Students' Research Committee, School of Nutrition and Food Science, University of Medical Sciences, Isfahan, Iran
2- M.Sc in Nutrition, Food Security Research Center, School of Nutrition and Food Science, University of Medical Sciences, Isfahan, Iran
3- Professor, Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, University of Medical Sciences, Isfahan, Iran , esmaillzadeh@hlth.mui.ac.ir
4- General Physician, Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
5- Associate Professor, Psychosomatic Research Center, Department of Psychiatry, Isfahan University of Medical Sciences, Isfahan, Iran
6- Associate Professor, Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran
7- Professor, Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:   (9775 Views)

Background and Objective: Although lifestyle-related factors have separately been examined in relation to functional gastrointestinal disorders (FGIDs), there is no epidemiologic data on the combined association of lifestyle factors with these conditions. We aimed to examine how combinations of several lifestyle factors were associated with functional dyspepsia (FD), its symptoms and gastro-esophageal reflux disease (GERD) in a large group of Iranian adults.

Methods: This descriptive -analytic study was conducted on 3363 Iranian adults (19-70 yr), whom were working in 50 health centers across Isfahan province in Iran during 2012. We used easy non-random sampling to select participants. The “healthy lifestyle score” for each participant was calculated by summing up the binary score given for five lifestyle factors, including dietary habits, dietary intakes, psychological distress, smoking and physical activity. A dish-based 106-item semi-quantitative validated food frequency questionnaire, General Practice Physical Activity Questionnaire, General Health Questionnaire and other pre-tested questionnaires were used to assess the components of healthy lifestyle score. A validated Persian version of ROME III questionnaire was used, to assess functional gastrointestinal disorders.

Results: The prevalence of FD and GERD among study participants was 14.5 and 23.6%, respectively. After adjustment for potential confounders, we found that individuals with the highest score of healthy lifestyle had 79 and 74% lower odds of FD (95% CI: 0.05-0.92, OR: 0.21, P=0.03) and GERD (95% CI: 0.09-0.69, OR: 0.26, P=0.01), respectively, compared with those with the lowest score. They were also less likely to have early satiation (95% CI: 0.11-0.73, OR: 0.28, P=0.001), postprandial fullness (95% CI: 0.09-0.50, OR: 0.22, P<0.001) and epigastric pain (95% CI: 0.21-0.92, OR: 0.44, P=0.03). In addition to the combined healthy lifestyle score, low levels of psychological distress, a healthy diet, healthy dietary habits and non-smoking were separately associated with FGIDs (P<0.05).

Conclusion: This study showed that adherence to a healthy lifestyle was associated with lower odds of GERD, FD and its symptoms in this group of Iranian adults. Individual lifestyle-related factors were also associated with these conditions.

Keywords: Healthy lifestyle, Functional dyspepsia, Gastro-esophageal reflux disease
Full-Text [PDF 788 kb] [English Abstract]   (11510 Downloads) |   |   Abstract (HTML)  (980 Views)  
Type of Study: Original Articles | Subject: Internal Medicine
1. Camilleri M, Dubois D, Coulie B, Jones M, Kahrilas PJ, Rentz AM, et al. Prevalence and socioeconomic impact of upper gastrointestinal disorders in the United States: results of the US Upper Gastrointestinal Study. Clin Gastroenterol Hepatol. 2005 Jun; 3(6): 543-52.
2. Sobieraj DM, Coleman SM, Coleman CI. US prevalence of upper gastrointestinal symptoms: a systematic literature review. Am J Manag Care. 2011 Nov; 17(11): e449-58.
3. El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014 Jun; 63(6): 871-80. doi:10.1136/gutjnl-2012-304269
4. Lacy BE, Talley NJ, Locke GR 3rd, Bouras EP, DiBaise JK, El-Serag HB, et al. Review article: current treatment options and management of functional dyspepsia. Aliment Pharmacol Ther. 2012 Jul; 36(1): 3-15. doi:10.1111/j.1365-2036.2012.05128.x
5. Eslick GD. Gastrointestinal symptoms and obesity: a meta-analysis. Obes Rev. 2012 May; 13(5): 469-79. doi:10.1111/j.1467-789X.2011.00969.x
6. Nandurkar S, Locke GR 3rd, Fett S, Zinsmeister AR, Cameron AJ, Talley NJ. Relationship between body mass index, diet, exercise and gastro-oesophageal reflux symptoms in a community. Aliment Pharmacol Ther. 2004 Sep; 20(5): 497-505.
7. Ruhl CE, Everhart JE. Overweight, but not high dietary fat intake, increases risk of gastroesophageal reflux disease hospitalization: the NHANES I Epidemiologic Followup Study. First National Health and Nutrition Examination Survey. Ann Epidemiol. 1999 Oct; 9(7): 424-35.
8. Jarosz M, Taraszewska A. Risk factors for gastroesophageal reflux disease: the role of diet. Prz Gastroenterol. 2014; 9(5): 297-301. doi:10.5114/pg.2014.46166
9. Feinle-Bisset C, Horowitz M. Dietary factors in functional dyspepsia. Neurogastroenterol Motil. 2006 Aug; 18(8): 608-18.
10. Yamamichi N, Mochizuki S, Asada-Hirayama I, Mikami-Matsuda R, Shimamoto T, Konno-Shimizu M, et al. Lifestyle factors affecting gastroesophageal reflux disease symptoms: a cross-sectional study of healthy 19864 adults using FSSG scores. BMC Med. 2012 May; 10:45. doi:10.1186/1741-7015-10-45
11. Pehl C, Pfeiffer A, Wendl B, Nagy I, Kaess H. Effect of smoking on the results of esophageal pH measurement in clinical routine. J Clin Gastroenterol. 1997 Oct; 25(3): 503-6.
12. Song JH, Chung SJ, Lee JH, Kim YH, Chang DK, Son HJ, et al. Relationship between gastroesophageal reflux symptoms and dietary factors in Korea. J Neurogastroenterol Motil. 2011; 17(1): 54-60. doi:10.5056/jnm.2011.17.1.54
13. El-Serag HB, Satia JA, Rabeneck L. Dietary intake and the risk of gastro-oesophageal reflux disease: a cross sectional study in volunteers. Gut. 2005; 54(1): 11-17. doi:10.1136/gut.2004.040337
14. Nilsson M, Johnsen R, Ye W, Hveem K, Lagergren J. Lifestyle related risk factors in the aetiology of gastro-oesophageal reflux. Gut. 2004 Dec;53(12):1730-5.
15. Nocon M, Labenz J, Willich SN. Lifestyle factors and symptoms of gastro-oesophageal reflux -- a population-based study. Aliment Pharmacol Ther. 2006 Jan; 23(1): 169-74.
16. Saito YA, Locke GR 3rd, Weaver AL, Zinsmeister AR, Talley NJ. Diet and functional gastrointestinal disorders: a population-based case-control study. Am J Gastroenterol. 2005 Dec; 100(12): 2743-8.
17. Hongo M. Epidemiology of FGID symptoms in Japanese general population with reference to life style. J Gastroenterol Hepatol. 2011; 26(Suppl 3): 19-22. doi:10.1111/j.1440-1746.2011.06632.x
18. Festi D, Scaioli E, Baldi F, Vestito A, Pasqui F, Di Biase AR, Colecchia A. Body weight, lifestyle, dietary habits and gastroesophageal reflux disease. World J Gastroenterol. 2009; 15(14): 1690-701. doi:10.3748/wjg.15.1690
19. Van Oudenhove L, Vandenberghe J, Geeraerts B, Vos R, Persoons P, Fischler B, Demyttenaere K, Tack J. Determinants of symptoms in functional dyspepsia: gastric sensorimotor function, psychosocial factors or somatisation? Gut. 2008 Dec; 57(12): 1666-73. doi:10.1136/gut.2008.158162
20. Esmaillzadeh A, Keshteli AH, Feizi A, Zaribaf F, Feinle-Bisset C, Adibi P. Patterns of diet-related practices and prevalence of gastro-esophageal reflux disease. Neurogastroenterol Motil. 2013 Oct; 25(10): 831-e638. doi:10.1111/nmo.12192
21. Keshteli AH, Feizi A, Esmaillzadeh A, Zaribaf F, Feinle-Bisset C, Talley NJ, et al. Patterns of dietary behaviours identified by latent class analysis are associated with chronic uninvestigated dyspepsia. Br J Nutr. 2015 Mar; 113(5): 803-12. doi:10.1017/S0007114514004140
22. Saneei P, Esmaillzadeh A, Keshteli AH, Feizi A, Feinle-Bisset C, Adibi P. Patterns of dietary habits in relation to obesity in Iranian adults. Eur J Nutr. 2016 Mar; 55(2): 713-28. doi:10.1007/s00394-015-0891-4
23. Keshteli A, Esmaillzadeh A, Rajaie S, Askari G, Feinle-Bisset C, Adibi P. A dish-based semi-quantitative food frequency questionnaire for assessment of dietary intakes in epidemiologic studies in Iran: design and development. Int J Prev Med. 2014 Jan; 5(1): 29-36.
24. Patino-Alonso MC, Recio-Rodríguez JI, Belio JF, Colominas-Garrido R, Lema-Bartolomé J, Arranz AG, et al. Factors associated with adherence to the Mediterranean diet in the adult population. J Acad Nutr Diet. 2014 Apr; 114(4): 583-9. doi:10.1016/j.jand.2013.07.038
25. Montazeri A, Harirchi AM, Shariati M, Garmaroudi G, Ebadi M, Fateh A. The 12-item General Health Questionnaire (GHQ-12): translation and validation study of the Iranian version. Health Qual Life Outcomes. 2003 Nov; 1: 66.
26. Esmaillzadeh A, Azadbakht L. Legume consumption is inversely associated with serum concentrations of adhesion molecules and inflammatory biomarkers among Iranian women. J Nutr. 2012 Feb; 142(2): 334-9. doi:10.3945/jn.111.146167
27. Sorouri M, Pourhoseingholi MA, Vahedi M, Safaee A, Moghimi-Dehkordi B, Pourhoseingholi A, et al. Functional bowel disorders in Iranian population using Rome III criteria. Saudi J Gastroenterol. 2010 Jul-Sep; 16(3): 154-60. doi:10.4103/1319-3767.65183
28. Zheng Z, Nordenstedt H, Pedersen NL, Lagergren J, Ye W: Lifestyle factors and risk for symptomatic gastroesophageal reflux in monozygotic twins. Gastroenterology. 2007; 132(1): 87-95. doi:10.1053/j.gastro.2006.11.019
29. Jiang SM, Lei XG, Jia L, Xu M, Wang SB, Liu J, Song M. Unhealthy dietary behavior in refractory functional dyspepsia: a multicenter prospective investigation in China. J Dig Dis. 2014 Dec; 15(12): 654-9. doi:10.1111/1751-2980.12199
30. Stake-Nilsson K, Hultcrantz R, Unge P, Wengström Y. Changes in symptoms and lifestyle factors in patients seeking healthcare for gastrointestinal symptoms: an 18-year follow-up study. Eur J Gastroenterol Hepatol. 2013 Dec; 25(12): 1470-7. doi:10.1097/MEG.0b013e328365c359
31. Emerenziani S, Zhang X, Blondeau K, Silny J, Tack J, Janssens J, et al. Gastric fullness, physical activity, and proximal extent of gastroesophageal reflux. Am J Gastroenterol. 2005 Jun; 100(6): 1251-6.
32. Pandolfino JE, Bianchi LK, Lee TJ, Hirano I, Kahrilas PJ. Esophagogastric junction morphology predicts susceptibility to exercise-induced reflux. Am J Gastroenterol. 2004 Aug; 99(8): 1430-6.
33. Parmelee-Peters K, Moeller JL. Gastroesophageal reflux in athletes. Curr Sports Med Rep. 2004 Apr; 3(2): 107-11.
34. Revicki DA, Wood M, Wiklund I, Crawley J. Reliability and validity of the Gastrointestinal Symptom Rating Scale in patients with gastroesophageal reflux disease. Qual Life Res. 1998 Jan; 7(1): 75-83.
35. Seyedmirzaei SM, Haghdoost AA, Afshari M, Dehghani A. Prevalence of dyspepsia and its associated factors among the adult population in southeast of iran in 2010. Iran Red Crescent Med J. 2014; 16: e14757.
36. Mostaghni A, Mehrabani D, Khademolhosseini F, Masoumi SJ, Moradi F, Zare N, et al. Prevalence and risk factors of gastroesophageal reflux disease in Qashqai migrating nomads, southern Iran. World J Gastroenterol. 2009; 15: 961-65.
Send email to the article author

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Saneei P, Hajishafiee M, Esmaillzadeh A, Hassanzadeh Keshteli A, Roohafza H, Afshar H, et al . Association between healthy lifestyle score and upper gastrointestinal disorders in Iranian adults . J Gorgan Univ Med Sci 2017; 19 (1) :54-66
URL: http://goums.ac.ir/journal/article-1-3018-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 19, Issue 1 (3-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
Persian site map - English site map - Created in 0.04 seconds with 36 queries by YEKTAWEB 4657