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:: Volume 18, Issue 4 (12-2016) ::
J Gorgan Univ Med Sci 2016, 18(4): 105-108 Back to browse issues page
Prevalence of medicinal drug interactionsin medicinal prescriptions in the Golestan province, Iran (2012)
A Abbasi1 , S Azadfar2 , GR Roshandel3 , SM Hoseini4 , R Golsha1 , B Khodabakhshi1 , Kh Amjadi5 , Hajimoradloo N * 6
1- Associate Professor, Infectious Diseases Research Centre; Golestan University of Medical Sciences, Gorgan, Iran
2- Ph.D Candidate in Cellular & Molecular Life Science, Infectious Diseases Research Centre; Golestan University of Medical Sciences, Gorgan, Iran
3- Assistant Professor, Golestan Research Center of Gastroenterology and Hepatology (GRCGH), Golestan University of Medical Sciences, Gorgan, Iran
4- General Physician, Golestan Health Insurance, Gorgan, Iran
5- M.Sc in Mathematical Statistics, Infectious Diseases Research Centre; Golestan University of Medical Sciences, Gorgan, Iran
6- General Physician, Infectious Diseases Research Centre; Golestan University of Medical Sciences, Gorgan, Iran , n.hajimoradloo@yahoo.com
Abstract:   (10307 Views)

Background and Objective: Medicinal drug interactions are one of the problems caused by irrational drug prescription. It eigher change the therapeutic effect or cause drug toxicity. This study was performed to determine the prevalence of medicinal drug interactions in medicinal prescriptions in Golestan province, north of Iran.

Methods: In this descriptive study, 1100000 medicinal prescriptions under contract with the Golestan province health insurance organization were assessed for drug interactions during 20 March-
20 September 2012.

Results: Drug interactions frequency was 6262 (0.66%). 35.5%, 63.1% and 1.4% of prescriptions were severe, moderate and mild interactions, respectively. The most common severe, moderate and mild drug interactions related to Atorvastatin-Gemfibrozil (13.67%), Ceftriaxone- Gentamicin (9.05%) and Lithium Carbonate-Haloperidol (2.56%).

Conclusion: In view of moderate and severe medicinal drug interactions in physicians' prescriptions, health system should plan a comprehensive program to improve awareness and effective monitoring to reduce medicinal drug interactions.

Keywords: Medicinal drug interactions, Medicinal prescription, Iran
Full-Text [PDF 152 kb] [English Abstract]   (18388 Downloads) |   |   Abstract (HTML)  (1300 Views)  
Type of Study: Short Communication | Subject: Pharmacology
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Abbasi A, Azadfar S, Roshandel G, Hoseini S, Golsha R, Khodabakhshi B, et al . Prevalence of medicinal drug interactionsin medicinal prescriptions in the Golestan province, Iran (2012). J Gorgan Univ Med Sci 2016; 18 (4) :105-108
URL: http://goums.ac.ir/journal/article-1-2964-en.html


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Volume 18, Issue 4 (12-2016) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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