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:: Volume 17, Issue 3 (10-2015) ::
J Gorgan Univ Med Sci 2015, 17(3): 63-68 Back to browse issues page
Effect of a session resistance exercise on mRNA expression of NT-3 and TrkC proteins in soleus muscle of Wistar rats
Eslami R * 1, Gharakhanlou R2 , Kazemi AR3 , Dabaghzadeh R4
1- Ph.D in Exercise Physiology, Department of Exercise Physiology, Kerman Branch, Islamic Azad University, Kerman, Iran , r_eslami1000@yahoo.com
2- Associate Professor, Department of Physical Education, Faculty of Humanity, Tarbiat Modares University, Tehran, Iran
3- Assistant Professor, Department of Physical Education, Vali-e-Asr Rafsanjan University, Rafsanjan, Iran
4- M.Sc Student in Exercise Physiology, Kerman Branch, Islamic Azad University, Kerman, Iran
Abstract:   (10920 Views)
Background and Objective: Skeletal muscle expresses several neurotrophin and their receptors which providing the basis for neurotrophin signaling within the muscle compartments. This study was done to evaluate the effect of a session of resistance exercise on mRNA expression of NT-3 and TrkC proteins in soleus muscle of Wistar Rats. Methods: In this experimental study, 16 male Wistar rats were randomly allocated into exercise and control groups. The resistance training protocol consisted of climbing a 1-meter–long ladder, with a weight attached to a tail sleeve. Expressions of NT-4/5 and P75, quantitatively were measured using RT-PCR. Results: There was not any significant alteration in NT-3 mRNA in soleus muscle after resistance exercise. However, one session of resistance exercise significantly increased mRNA expression of TrkC (1.7 Folds) in soleus muscle (P<0.05). Conclusion: Resistance exercise increases TrkC expression in soleuse muscle of wistar rats.
Keywords: Soleus muscle, Resistance exercise, Neurotrophin-3 (NT-4/5), TrkC receptor, Rat
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Type of Study: Original Articles | Subject: Genetic
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Eslami R, Gharakhanlou R, Kazemi AR, Dabaghzadeh R. Effect of a session resistance exercise on mRNA expression of NT-3 and TrkC proteins in soleus muscle of Wistar rats. J Gorgan Univ Med Sci 2015; 17 (3) :63-68
URL: http://goums.ac.ir/journal/article-1-2502-en.html


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Volume 17, Issue 3 (10-2015) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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