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Cardiovascular autonomic neuropathy among non- insulin dependent diabetics patients
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Hosseini SM *   1, Maleki AR2 , Bazrafshan HR3 |
1- Associate Professor, Department of Physiology, Neuroscience Research Center, Medical Faculty, Golestan University of Medical Sciences, Gorgan, Iran , hosseini@goums.ac.ir
2- General Physician
3- Associate Professor, Department of Internal Medicine, Medical Faculty, Golestan University of Medical Sciences, Gorgan, Iran |
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Abstract: (9818 Views) |
| Background and Objective: Cardiovascular autonomic neuropathy (CAN) is the most common and important type of diabetic autonomic neuropathy. Silent myocardial infarction, respiratory failure and increased mortality are the outcomes of CAN. This study was carried out to screen the cardiovascular autonomic neuropathy in non- insulin dependent diabetics patients. Method: This descriptive - analytic study was carried on 70 (22 males, 48 females) non- insulin dependent diabetics’ patients. Resting heart rate, heart rate variability, orthostatic changes in heart rate, blood pressure and corrected QT interval were recorded for each subject. The final findings were categorized as follow: 0=normal, 1=borderline and 2=CAN positive. Results: 10 (14.3%) of patients were normal, 35 (50%) of patients were borderline and 25 (35.7%) of patients were considered cardiovascular autonomic neuropathy positive. There was significant differences between duration of diabetes and three CAN scores (P<0.05). The systolic blood pressure alterations showed the maximum correlation with CAN scores (r=0.509). Conclusion: In our study, the rate of cardiovascular autonomic neuropathy was higher than other reports. The most important risk factor for cardiovascular autonomic neuropathy was more than 10 years history of diabetes mellitus. |
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| Keywords: Diabetes mellitus, Cardiovascular autonomic neuropathy, Hypertension |
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Full-Text [PDF 370 kb]
[English Abstract]
(9475 Downloads)
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Type of Study: Original Articles |
Subject:
Internal Medicine
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