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:: Volume 3, Issue 1 (Spring & Summer 2001) ::
J Gorgan Univ Med Sci 2001, 3(1): 11-16 Back to browse issues page
Comparison of intraocular pressure changes during induction of anesthesia with Midazolam and Propofol in ophthalmologic surgery
V.Hasani (M.D) , M.M.Mirsamadi (M.D) , E.Hasheminezhad (MD) * 1
Abstract:   (16725 Views)
One of the major determinative of the outcome of the ophthalmologic surgeries, is how efficiency the anesthesiologist can lower the intraocular pressure (IOP) and prevent it from rising in response to such maneuvers as laryngoscopy and tracheal intubation. In our study, we have chosen Midazolam and Propofol for comparing their effects on IOP during induction of anesthesia, laryngoscopy and tracheal intubation, with the purpose of identifying the drug which can more effectively decrease IOP and prevent it’s during laryngoscopy and tracheal intubation. 100 patients were selected randomly and received either Midazolam 0.2 mg/kg, Sufentanil 0.2 microgram/kg, Atracurium 0.5 mg/kg (Group 1) or Propofol 2.5 mg/kg, Sufentanil 0.2 microgram/kg, Atracurium 0.5 mg/kg (Group 2). The IOP was measured before and after induction and immediately after intubation. Both groups showed a meaningful decrease in IOP following induction of anesthesia (P?0.0001). Laryngoscopy and intubation, increased IOP in group 1, however not significantly and still lower than the base line IOP (P=0.09). Group 2 showed no such increase (P<0.0001). We concluded that Propofol in comparison to Midazolam is more effective in prevention of IOP rise in response to laryngoscopy and tracheal intubation.
Keywords: Midazolam, Propofol, Intraocular pressure
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Type of Study: Original Articles | Subject: General
* Corresponding Author Address: elhasheminenejad@hotmail.com


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V.Hasani (M.D), M.M.Mirsamadi (M.D), E.Hasheminezhad (MD). Comparison of intraocular pressure changes during induction of anesthesia with Midazolam and Propofol in ophthalmologic surgery . J Gorgan Univ Med Sci 2001; 3 (1) :11-16
URL: http://goums.ac.ir/journal/article-1-115-en.html


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Volume 3, Issue 1 (Spring & Summer 2001) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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