Jorjani Biomedicine Journal
فصلنامه علمی پژوهشی زیست پزشکی جرجانی
Jorjani Biomed J
Medical Sciences
http://goums.ac.ir/jorjanijournal
1
admin
2645-3509
10.52547/jorjanibiomedj
en
jalali
1398
12
1
gregorian
2020
3
1
8
1
online
1
fulltext
en
The Effect of High Intensity Interval Training with Genistein on Biomechanical Properties of Femur Bone in Elderly Female Rats
بهداشت
Health
تحقیقی
Original article
<div style="text-align: justify;"><strong><em>Background and objective</em></strong>: Proper exercise and nutrition can help prevent bone disorders in old age, therefore present study aimed to investigate the effects of high intensity interval training (HIIT) with genistein (Ge) on biomechanical properties of femur bone in elderly female rats.<br>
<strong><em>Material and Methods:</em></strong> In this experimental study, 40 elderly female rats with mean age of 18- 24 months and mean weight of 220.15±15.28 g were divided into five groups of eight rats including: 1) control (C), 2) sham (Sh), 3) HIIT, 4) HIIT + Ge, and 5) Ge. During eight weeks groups 3 and 4 performed HIIT for three sessions per week with an intensity of 90 to 95% of maximum oxygen consumption (VO2max) in high intensity intervals and 40 to 45% VO2max in low intensity intervals and groups 4 and 5 received 60 mg/kg/day Ge peritoneally. Maximum bending strength (Fmax) measured with three- point bending test and serum levels of calcium (Ca) and phosphorus were measured by o-Cresolphthalein and molybdate methods, respectively. Shapiro- Wilk, one way ANOVA with Tukey’s post- hoc tests were used for analysis of data (P≤0.05).<br>
<strong><em>Results:</em></strong> HIIT (P=0.02), Ge (P=0.001) and HIIT+Ge (P=0.001) significantly increased Fmax also Ge (P=0.04) and HIIT+Ge (P=0.03) had more favorable effect on increasing Fmax compare to HIIT nevertheless HIIT, Ge and HIIT+Ge had not significant effect on Ca and phosphorus (P≥0.05).<br>
<strong><em>Conclusion:</em></strong> Although HIIT and Ge alone can enhance Fmax in femur of elderly female rats, nevertheless HIIT+Ge has more favorable effect on increase of Fmax compare to HIIT.</div>
Exercise,Genistein,Biomechanical,Properties,Femur,
51
59
http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-723-1&slc_lang=en&sid=1
Farideh
Kaikhosravi
farideh.fahim@yahoo.com
10031947532846006116
10031947532846006116
No
Department of Sport Sciences, Shiraz University, Iran
Farhad
Daryanoosh
daryanoosh@shirazu.ac.ir
10031947532846006117
10031947532846006117
Yes
Department of Sport Sciences, Shiraz University, Iran
Maryam
Koushkie Jahromi
koushkie53@yahoo.com
10031947532846006118
10031947532846006118
No
Department of Sport Sciences, Shiraz University, Iran
Javad
Nemati
nemati_phy@yahoo.com
10031947532846006119
10031947532846006119
No
Department of Sport Sciences, Shiraz University, Iran