TY - JOUR T1 - Interactive effects of eight weeks massage therapy along with Apium graveolens seed consumption on serum levels of IGF-1 and P53 in overweight women TT - تأثیر تعاملی هشت هفته ماساژ به همراه مصرف دانه کرفس (Apium graveolens) بر سطوح سرمی IGF-1 و P53 در زنان دارای اضافه وزن JF - Jorjani-Biomedicine-Journal JO - Jorjani-Biomedicine-Journal VL - 2 IS - 1 UR - http://goums.ac.ir/jorjanijournal/article-1-248-en.html Y1 - 2014 SP - 26 EP - 18 KW - Massage Therapy KW - Celery KW - IGF-1 KW - P53 N2 - Background & Objective: High blood levels of IGF-1 in women before menopause, is a risk factor and P53 tumor suppressor gene is also one of the most common genes involved in breast cancer. Since some studies demonstrated that physical activity and compounds found in Celery have anti-cancer effects, this study aimed to investigate the interactive effects of eight weeks massage therapy along with celery seed supplementation on the levels of IGF-1 and P53 in overweight women. Method: In a single, blind, placebo-controlled clinical trial, the interactive effects of eight weeks massage therapy along with celery seed consumption on IGF-1 and P53 serum concentrations in overweight women were measured. For this purpose, 28 overweight women with a BMI of more than 25 kg/m2 in Ghaemshahr were randomly divided into four groups. Weight and serum levels variables of IGF-1 and P53, prior and after the therapy were measured. Then the data were analyzed using t-test and one-way variance analysis. P M3 ER -