Search published articles


Showing 2 results for بتا تالاسمی ماژور

Samaneh Homayouni-Meymandi, Sayed Hamid Sayednezhad-Golkhatmi, Nour Mohammad Bakhshani,
Volume 2, Issue 1 (5-2014)
Abstract

Background & Objective: Beta-thalassemia major, impairs body and central nervous system functions. Decline in Perceptual and cognitive abilities in this disease, especially in children, and eventual reduced quality of life, is one of the possible complications of this disease. The purpose of this study was to evaluate the cognitive perception of two abilities to think abstractly and visual organization in children with beta-thalassemia major and healthy counterparts. Method: This cross-sectional study was conducted in year 1391, using convenient sampling in cities of Zahedan and Shiraz. After matching children in terms of age, gender and city of residence, 40 children with beta-thalassemia major and 40 matched healthy children aged 6-12 years were compared, using the independent t-test and Wechsler Intelligence Scale for Children revision (WISC-R) in terms of abstract thinking and visual organization. Results: There was a statistically significant difference in evaluation of abstract thinking between the average score of sick children 9.81 ± 1.64 and the average score of healthy counterparts 10.82 ± 1.05 (P<0.01). Also in assessment of visual organization, the average score of sick children 10.23 ± 1.09 and the average score of healthy counterparts 10.72 ± 0.66 were significantly different(P<0.01). Conclusion: The results show the potential impact of the disease on children›s cognitive levels and suggest that children with beta-thalassemia major need more attention in the field of education to promote their understanding.
Samaneh Homayouni-Meyamndi, Noormohammad Bakhshani,
Volume 3, Issue 2 (10-2015)
Abstract

Background and Objective: β-Thalassemia major is a chronic genetic disease which is determined with symptoms and signs of a chronic severe anemia. Children with β-Thalassemia major have several risk factors for cognitive problems. The purpose of this study was to compare the cognitive function in β-thalassemia major children and healthy counterparts.

Methods: This cross-sectional study was conducted in 1391, using convenient sampling method in Zahedan and Shiraz cities. After matching children in terms of age, gender and city of residence, 40 children with β-thalassemia major and 40 matched healthy 6-12 year old children were compared using the independent t-test and Wechsler Intelligence Scale for Children Revision (WISC-R) in terms of verbal understanding, organizing perceptual and freedom from distraction. Data were expressed in descriptive ways and independent t-test was used to analyze data using spss 18 software.

Results: Children with β-Thalassemia major gained low scores in the areas of verbal understanding (P=0.01) and freedom from distraction (P=0.01) significantly in comparison to healthy counterparts, but no significant difference was observed in the area of organizing perceptual index (P=0.29) not difference between the two groups.

Conclusion: Children with β-Thalassemia major do not necessarily face cognitive decline and are slightly lower than their healthy counterparts and require more attention in the field of education, to improve the quality of their knowledge.



Page 1 from 1     

© 2024 CC BY-NC 4.0 | Jorjani Biomedicine Journal

Designed & Developed by : Yektaweb