Jorjani Biomedicine Journal

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Background & Objective: Nasopharynx could be affected by many tumors types such as carcinoma and lymphoma. These tumors present specific manifestations and symptoms. In rare cases these tumors can present unusual symptoms and without careful attention could be missed. In the present article we have described a rare case of nasopharyngeal tumor which a mass in cheeks.

Case presentation: A 72 year-old female who presented inflammation and a mass in left cheek, nasal obstruction in right nose was referred to CTS department and coronal view of paransal sinus was performed. Because sinuses were intact, patient was treated with antibiotic and antiallergic drugs. In spite of medical therapies, cheek mass growth continued and CTS was repeated in coronal and axial view. In these images, a mass in left Nasopharynx and a polypoid mass in right nasal cavity were found. Patient was undergone endoscopic surgery and biopsies were done from those sites .Pathologist reported a nasal polyp in right nose and an undifferentiated carcinoma of left Nasopharynx and cheek. Immunohistochemistry investigation for differentiated tumor from lymphoma was done and confirmed the lymphoma. Patient was refereed to oncologist for further treatment.

Conclusion: In management of patient we should consider unusual presentation of nasopharyngeal lymphoma with cheek mass which is an unusual presentation of this tumor.

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Background: Disorders of sex development (DSD) are a medical condition that affects the normal process of sexual  Various of the genes needed for gonad development have been identified by investigation of patients with disorders sex development (DSD).Phenotypes of patients with 46,XY DSD range from atonalism in female phenotype with complete external  genitalia to male phenotype with testicular regression. Individuals with 46,XYagonadiam show a wide range of clinical features and in some cases, there is not a clear diagnosis for this patients. We presented the clinical and molecular study a patient with 46,XY female without gonadal tissue.
Case presentation: A 27-year-old female was attended to our center because of primary amenorrhea. Ultrasonography did not show gonadal tissue including Mullerian structures, uterus, and Wolffian structures. Also, the patient had not streak gonad. We performed cytogenetic study and molecular analysis, including automated sequencing of the entire coding region of SRY gene, in the patient with agonadism. Our result showed 46,XY karyotype. Also, we noticed that molecular mutations in SRY are not identified as a cause of DSD female without a gonadal tissue. Laboratory examination showed that this case is a unique patient with 46,XYfemale agonadism that has no association with previously described.
Conclusions: The present case was a patient with 46, XYagonadism without hormonal or kidney defect and we did not detect mutation in SRY gene. To our knowledge, this case is a unique patient with 46,XYagonadism that has no association with previously described. So this case would be helpful for clinicians to assess 46,XY female patients without gonadal tissue.
 

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Background: Supernumerary teeth are known as the teeth in excess of the normal dentition. Multiple supernumerary teeth are usually observed as having syndromes. Conversely, multiple supernumerary teeth without any associated systemic conditions or syndromes are not common. 
Case presentation: This article documents an unusual case report, a male patient with non-syndromic 10 supernumerary teeth in both jaws, an incidental finding during routine radiographic examination. 
Conclusion: CBCT is the best diagnostic imaging method currently available for determining the relationships of teeth and the surrounding structures in cases with multiple impacted teeth or severe overlapping of impacted teeth.

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A Dentigerous Cyst (DC) is the most common developmental odontogenic cyst that mostly happens in patients between 10 to 30 years of age. It is usually completely asymptomatic and is discovered on a routine radiographic examination or to evaluate the reason for an erupted tooth. Radiographically, this cyst usually presents a well-defined unilocular radiolucency attached to CEJ of an unerupted tooth which can cause displacement of adjacent tooth or resorption.
This article reports a large infected DC in a 10-year-old male patient related to first and second premolar maxillary teeth, which did not erupt or even change their positions. DC was treated successfully by decompression. After 2 years follow up, there was no evidence of recurrence. In conclusion, marsupialization of cyst with no orthodontic intervention or tooth extraction is a conservative, efficient protocol that stimulates bone healing and promotes the eruption of unerupted teeth even if they are deeply crowded.

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This article reports a pelvic hydatid cyst in a 10-year-old boy who initially presented with right flank pain. Computed tomography (CT) revealed a cystic lesion containing internal densities, which was found to be a hydatid cyst between the bladder and rectum during surgery. The lesion was excised and sent to a pathology laboratory for further examination.

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