en بهداشت Health تحقیقی Original article <a href="http://jorjanijournal.goums.ac.ir/search.php?sid=1&slc_lang=en&author=Jadidi">Samaneh Jadidi</a>,<a href="https://scholar.google.com/citations?hl=en&user=W14rSQkAAAAJ">&nbsp;Seyed Mohsen Avandi</a>&nbsp;<a href="http://orcid.org/0000000256270435" target="_blank" title="http://orcid.org/0000000256270435"><img alt="" src="http://jorjanijournal.goums.ac.ir/files/0allsites/images/orcid.png" ></a>,&nbsp;<a href="http://jorjanijournal.goums.ac.ir/search.php?sid=1&slc_lang=en&author=Khaleghian">Ali Khaleghian</a><br> <span style="font-size:14px;"><span new="" roman="" style="font-family:" times=""><b>Background</b>: <span lang="EN">Obesity is one of the most serious health problems associated with inflammation. It has been found that functional and resistance physical activities improve obesity and inflammation. The aim of this study was to investigate the effect </span>High-intensity Functional<b> </b><span lang="EN">training (HIFT) and Circuit resistance training (CRT) on serum levels of the pro-inflammatory factor interferon gamma (</span>IFN-&gamma;<span lang="EN">) in obese women.</span> <span dir="RTL" lang="AR-SA"><span style="font-family:F"></span></span></span><br> <span new="" roman="" style="font-family:" times=""><b><span lang="EN">Methods</span></b><span lang="EN">: Thirty</span><span dir="RTL" lang="AR-SA"><span style="font-family:F">-</span></span><span lang="EN">six obese women of Semnan city (age: 32.66 &plusmn; 3.91, weight: 86.97</span><span dir="RTL" lang="AR-SA"><span style="font-family:F">&plusmn; </span></span><span lang="EN">9.08 and BMI> 30) were selected and divided into three groups of HIIF (n =12), CRT (n = 12) and control (n = 12) were divided. HIIF was performed in the form of cross-fit exercises and Circuit exercises in the form of weight training for 6 weeks. Finally, the IFN-&gamma; was measured using the Human IFN-g Elisa kit 96t-zellbio. To examine the data, one-way analysis of variance and dependent t-test at the level of p&le;0.05 were used and all calculations were performed using SPSS software version 24. </span></span><br> <span new="" roman="" style="font-family:" times=""><b>Results</b><span lang="EN">: The results showed that there was no significant change in IFN-&gamma; level in training groups compared to before training (P</span>><span lang="EN">0.05). Also, the results between groups did not show a significant difference in serum IFN-&gamma; between HIIF and CRT (P</span>><span lang="EN">0.05).</span> <span style="font-size:8.0pt"></span></span><br> <span new="" roman="" style="font-family:" times=""><b>Conclusion</b>: Therefore, it seems that of exercise does not affect the dependent variable of serum interferon gamma levels.</span></span> High-intensity functional training, Circuit resistance training, Interferon gamma, Obesity 9 12 http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-931-1&slc_lang=en&sid=1 Samaneh Jadidi 100319475328460010758 100319475328460010758 No Sport Science Department, Human Faculty, Semnan University, Semnan, Iran Seyed Mohsen Avandi m.avandi@semnan.ac.ir 100319475328460010759 0000000256270435 Yes Sport Science Department, Human Faculty, Semnan University, Semnan, Iran Ali Khaleghian 100319475328460010760 100319475328460010760 No Biochemistry Department, Semnan University of Medical sciences, Semnan, Iran